Whole-body vibration treatment in prostate cancer survivors on androgen suppression therapy
More than 2,000 men in Australia commence on-going androgen suppression therapy (AST) for prostate cancer each year. AST leads to many toxicities including reduced bone density and increased skeletal fractures. Whole-body vibration training is a relatively new form of therapy that has been shown in certain populations to improve bone density. This study aims to examine the effect of vibration training on markers of bone health in prostate cancer survivors on androgen suppression therapy (AST). We will compare 12 weeks of vibration training (3 times per week) with usual care control. We hypothesize the application of vibration stimulus for 12 weeks will decrease bone resorption (breakdown) compared with a usual care control group. This will be the first study to investigate this novel therapy for improving skeletal health of men with prostate cancer on AST.