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Hyperspectral retinal imaging in preclinical Alzheimer’s disease research project

Are you thinking of furthering your career with a research degree and solving real world problems? ECU is seeking a PhD candidate to undertake research in hyperspectral retinal imaging in preclincal Alzheimer's disease under the School of Medical and Health Sciences. Scholarship opportunities may be available for the right candidate.


Important dates

Opens: 1-09-2017 Closes: 15-12-2017

Applies to

Domestic International Postgraduate Research

Scholarship opportunities

If you are interested in this research project there are a range of scholarship opportunities that may be available to you. Check out the links below to familiarise yourself with the eligibility guidelines of each scholarship:

Project overview

There is still no definitive pre-mortem diagnosis for Alzheimer’s disease (AD) and the current gold standard markers are either invasive or expensive for population wide screening. The advertised Ph.D. position will investigate changes occurring in the retina in the eyes of study participants using a breakthrough NASA inspired technology and its relationship with changes occurring in the brain. This will enable us to identify potential biomarkers in the eye for the early diagnosis of AD in a highly-characterized cohort that include participants in the preclinical stage of AD, as assessed from the brain beta amyloid load, a gold standard marker of AD.

Hypothesis: AD pathogenesis-related biomarkers in the retina can identify pre-clinical Alzheimer’s disease.

Aims: Identify retinal biomarkers in the eyes of individuals in the preclinical phase of AD versus healthy control individuals, and validate findings in an independent cohort.

Methods: Hyperspectral retinal imaging will be performed using state of the art metabolic hyperspectral retinal camera (MHRC) along with other cognitive and retinal assessments, blood biomarker analysis and brain imaging. The MHRC has been donated by the Lions Alzheimer’s Foundation for this project and is one of the only three currently available in Australia (the second camera is at our Sydney site, at Macquarie University).

How to apply

Check our Entry Requirements page for details about your eligibility. You can apply for a Higher Degree by Research via the ECU Application Portal once you have your documentation together.

Enquiries

For more information regarding the research project, please contact:

Professor Ralph Martins AO
Email: r.martins@ecu.edu.au

Dr Tejal Shah
Email: tejal.shah@ecu.edu.au

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