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Dr Anna Callan

Lecturer

Current Teaching

• Lab demonstrator for units SCB2222 and SCB3322

Background

• 2009-present: Postdoctoral Research Fellow, Edith Cowan University
  
• 2008-2009: Research Officer, Telethon Institute for Child Health Research
• 2006-2007: Postdoctoral Research Associate Faculty of Life Sciences, University of Manchester
  

Human Exposure to Environmental Contaminants and Associated Health Effects

• Exposure of susceptible groups, such as children, to persistent toxic substances and the resulting effects of exposure
• Assessment of the contribution of dietary exposure to persistent toxic substances to an individual’s total level of exposure.
• Monitoring the biological effects of persistent toxic substance exposure as determined by the measurement of biomarkers of disease, oxidative damage and DNA modifications

I obtained my PhD in Biochemistry/Cell Biology however the focus of my research has changed recently and I am now involved in a number of projects relating to environmental exposures and their health effects. I am currently involved in a number of research projects which include investigating the exposure of pregnant women to a range of environmental contaminants (metals, pesticides and persistent organic compounds) and children’s exposure to metals, emerging pollutants and particulate matter.

However, my background in biological sciences means that I am keen to explore ways of investigating not just personal exposure to environmental contaminants, but also the health effects of exposure and the biological mechanisms underlying those effects. I am particularly interested in environmental contaminants relating to health outcomes in susceptible population groups such as young children and the elderly. The effect of pre-natal exposure to environmental contaminants on pregnancy and birth outcomes is also an area of considerable interest to me. In addition I am keen to explore the contribution of dietary exposure of metals and pollutants to an individual’s total exposure.

• Environment exposure
• Biological effects of exposure to environmental contaminants
• Contribution of diet to exposure to metals and other contaminants

Staff Qualifications

• Doctor of Philosophy, England, 2006 .
• Master, England, 2002 .
• Bachelor of Science, England, 2001 .

Research

Recent Research Grants

• Children's exposure to PM10 and Metals in Perth,  Edith Cowan University,  ECU Industry Collaboration - Grant,  2011,  $28,526.
• Particulates, Metals and Human Exposure,  Telethon Institute for Child Health Research,  Grant,  2011,  $9,091.
• Particulates, Metals and Human Exposure,  Telethon Institute for Child Health Research,  Grant,  2009,  $29,794.

Recent Publications (within the last five years)

Journal Articles

• McQueen, HL., Callan, A., Hinwood, A., (2012), Estimating Maternal and Prenatal Exposure to Glyphosate in the Community Setting. International Journal Hygiene and Environmental Health, 215(6), 570-576, DOI: 10.1016/j.ijheh.2011.12.002.
• Callan, A., Hinwood, A., Heffernan, A., Eaglesham, G., Mueller, J., Odland, J., (2012), Urinary Bisphenol A concentrations in Pregnant Women. International Journal Hygiene and Environmental Health, N/A(N/A), N/A, DOI: 10.1016/j.ijheh.2012.10.002.
• Lazenby, V., Hinwood, A., Callan, A., Franklin, P., (2012), Formaldehyde Personal Exposure Measurements and Time Weighted Exposure Estimates in Children. Chemosphere, 88(8), 966-973, United Kingdom, DOI: 10.1016/j.chemosphere.2012.03.029.
• McKibbin, C., Mares, A., Piacenti, M., Williams, H., Roboti, P., Puumalainen, M., Callan, A., Lesiak-Mieczkowska, K., Linder, S., Harant, H., High, S., Flitsch, S., Whitehead, R., Swanton, E., (2012), Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response. Biochemical Journal, 442(N/A), 639-648, DOI: doi:10.1042/BJ20111220.
• Callan, A., Winters, M., Barton, C., Boyce, M., Hinwood, A., (2011), Children's Exposure to Metals: A Community-Initiated Study. Archives of Environmental Contamination and Toxicology, N/A(N/A), N/A, DOI: 10.1007/s00244-011-9727-2.
• Callan, A., Hinwood, A., (2011), Exposures to lead. Reviews on Environmental Health, 26(1), 13-15, DOI: 10.1515/REVEH.2011.003.
• Cross, B., McKibbin, C., Callan, A., Roboti, P., Piacenti, M., Rabu, C., Wilson, C., Whitehead, R., Flitsch, S., Pool, M., High, S., Swanton, E., (2009), Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. Journal of Cell Science, 122(23), 4393-4400, United Kingdom, DOI: 10.1242/jcs.054494.
• Callan, A., Milne, E., (2009), Involvement of the IGF system in fetal growth and childhood cancer: an overview of potential mechanisms. Cancer Causes and Control, 20(10), 1783-1798, The Netherlands, DOI: 10.1007/s10552-009-9378-z.