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Research Fellow

Telephone:	(61 8)  6304 5838
Email:	v.gupta@ecu.edu.au
Campus:	Joondalup
Room:	JO17.107

 

Staff Qualifications

• PhD (Doctoral Degree), India, 2009 .
• M (Master Degree), India, 2002 .
• B (Bachelor Degree), India, 2001 .

Research

Recent Research Grants

• Discovery and Validation of Alzheimers Biomarkers in Human Plasma,  National Health and Medical Research Council,  Project Grants,  2011,  $119,623.

Recent Publications (within the last five years)

Books

• Gupta, V., (2012), Alpha-1 Proteinase Inhibitor in Action: Roles and Mechanistic Insights., 200, Europe.
• Gupta, V., Gupta, V., (2012), Molecular Mechanisms and Therapeutic Strategies in Alzheimer's Disease., n/a, Europe.

Journal Articles

• Steele, J., Su, J., Lachenmayer, L., Liken, J., Stock, A., Kim, S., Delgado, L., Alfaro, I., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S., (2012), Latrepirdine stimulates autophagy and reduces accumulation of a-synuclein in cells and in mouse brain. Molecular Psychiatry, n/a(n/a), 1-7, United Kingdom, DOI: 10.1038/mp.2012.115.
• Gupta, V., (2012), Associations between gonadotropins, testosterone and ? amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry, n/a(n/a), n/a, United Kingdom.
• Gupta, V., (2012), Studies on the mechanism of the DNA nicking property of amyloid-?40: implications in Alzheimer's disease. Journal of Alzheimer's Disease, n/a(n/a), n/a, Netherlands.
• Steele, JW., Lachenmayer, ML., Ju, S., Stock, A., Liken, J., Kim, SH., Delgado, LM., Alfaro, IE., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Fraser, P., Westaway, D., St George-Hyslop, P0., Szabo, P., Relkin, N0., Buxbaum, J0., Glabe, C0., Protter, A0., Martins, R., Ehrlich, M0., Petsko, G0., (2012), Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry, 1-9, United Kingdom, DOI: 10.1038/mp.2012.106.
• Brown, B., Peiffer, J., Sohrabi, H., Mondal, A., Gupta, V., Rainey-Smith, S., Taddei, K., Burnham, S., Ellis, K., Szoeke, C., Masters, CL., Ames, D., Rowe, C., Martins, R., (2012), Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2(n/a), art. no. e191 , DOI: 10.1038/tp.2012.118.
• Bharadwaj, P., Verdile, G., Barr, R., Gupta, V., Steele, J., Lachenmayer, L., Yue, Z., Ehrlich, M., Petsko, G., Ju, S., Ringe, D., Sankovich, S., Caine, J., Macreadie, I., Gandy, S., Martins, R., (2012), Latrepirdine (Dimebon?) enhances autophagy and reduces intracellular GFP-A?42 levels in yeast. Journal of Alzheimer's disease, 32(4), 949-967, Netherlands, DOI: 10.3233/JAD-2012-120178.
• Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoecke, C., Taddei, K., Villemagne, V., Martins, R., (2012), Associations between gonadotropins, testosterone and ? amyloid in men at risk of Alzheimer?s disease. Molecular Psychiatry, 7, United Kingdom, DOI: 10.1038/mp.2012.147.
• Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, SL., Szoecke, C., Rowe, C., Martins, R., (2012), Physical activity and amyloid-b plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, n/a(n/a), 1-7, United Kingdom, DOI: 10.1038/mp.2012.107.
• Gupta, V., (2012), Physical activity and amyloid beta plasma and brain levels: Results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, n/a(n/a), n/a, United Kingdom.
• Doecke, J., Laws, S., Faux, N., Wilson, W., Burnham, S., Lam, P., Mondal, A., Bedo, J., Bush, A., Brown, B., De Ruyck, K., Ellis, K., Fowler, C., Gupta, V., Head, R., Macaulay, SL., Pertile, K., Rowe, C., Rembach, A., Rodrigues, M., Rumble, R., Szoeke, C., Taddei, K., Taddei, T., Trounson, B., Ames, D., Masters, C., Martins, R., (2012), Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease. Archives of Neurology, 69(10), 1318-1325, United States, DOI: 10.1001/archneurol.2012.1282.
• Steele, JW., Ju, S., Lachenmayer, M., Liken, J., Stock, A., Kim, SH., Delgado, L., Alfaro, I., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S., (2012), Latrepiridine stimulates autophagy and reduces accumulation of alpha-synuclein in cells and in mouse brain. Molecular Psychiatry, n/a(n/a), n/a, United Kingdom, DOI: 10.1038/mp.2012.115.
• Gupta, V., (2012), Autophagy and Reduces Intracellular GFP-A?42 Levels in Yeast. Journal of Alzheimer's Disease, n/a(n/a), n/a, Netherlands.
• Gupta, V., (2012), Biomarkers of Alzheimer?s Disease Among Mexican Americans. Journal of Alzheimer's Disease, n/a(n/a), n/a, Netherlands.
• Gupta, V., Laws, S., Villemagne, V., Ames, D., Bush, A., Ellis, K., Lui, J., Masters, C., Rowe, C., Szoeke, C., Taddei, K., Martins, R., (2011), Plasma apolipoprotein e and Alzheimer disease risk: The AIBL study of aging. Neurology, 76(12), 1091-1098, DOI: 10.1212/WNL.0b013e318211c352.
• Lui, J., Laws, S., Li, Q., Villemagne, V., Ames, D., Brown, B., Bush, A., De Ruyck, K., Dromey, J., Ellis, K., Faux, N., Foster, J., Fowler, C., Gupta, V., Hudson, P., Laughton, K., Masters, C., Pertile, K., Rembach, A., Rimajova, M., Rodrigues, M., Rowe, C., Rumble, R., Szoecke, C., Taddei, K., Taddei, T., Trounson, B., Ward, V., Martins, R., (2010), Plasma amyloid-? as a biomarker in Alzheimer?s disease: the AIBL study of aging. Journal of Alzheimer's Disease, 20(4), 1233-1242, Netherlands, DOI: 10.3233/JAD-2010-090249.
• Gupta, V., Indi, SS., Rao, KS., (2009), Garlic Extract Exhibits Antiamyloidogenic Activity on Amyloid-beta Fibrillogenesis: Relevance to Alzheimer?s Disease. Phytotherapy Research, 23(1), 111-115, United Kingdom, DOI: 10.1002/ptr.2574.