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Dr Stephanie Rainey-Smith

Dr Stephanie Rainey-Smith

Clinical Trials Coordinator

Contact Information Telephone: (61 8)  6304 2649 , Email: s.rainey-smith@ecu.edu.au, Campus: JO, Room: JO17.310,
Staff Member Details
Telephone: (61 8)  6304 2649  
Email: s.rainey-smith@ecu.edu.au   
Campus: Joondalup  
Room: JO17.310  

 

Stephanie is a Clinical Trials Coordinator within the School of Medical Sciences.

Qualifications

  • PhD (Doctoral Degree), United Kingdom, 2010.
  • B (Bachelor Degree), United Kingdom, 2001.

Research

Recent Research Grants

  • Impact of genetics on the effect that modifiable lifestyle factors have on rates of change in Alzheimers Disease,  Equity Trustees Limited,  Mason Foundation National Medical Program (funded by the J. J. Mason & H.S. Williams Memorial Foundation),  2016 - 2017,  $55,370.
  • Development and refinement of methods for early and specific diagnosis of Alzheimer's disease, quantification of rates of change in the pathological processes and determination of the resultant effects on cognition.,  Fil Foundation,  Grant,  2015 - 2017,  $417,506.
  • The contribution of sleep factors to healthy cognitive ageing: A pilot sleep-specific cognitive behavioural intervention study,  Equity Trustees Limited,  Mason Foundation National Medical Program (funded by the J. J. Mason & H.S. Williams Memorial Foundation),  2015 - 2017,  $60,000.
  • Short chain fatty acids are a useful therapy for the treatment of Alzheimer's Disease. ,  Hollywood Private Hospital Research Foundation,  Grant,  2013 - 2016,  $20,000.
  • CSIRO/Janssen AIBL Neuroscience Program,  Commonwealth Scientific and Industrial Research Organisation (CSIRO),  Janssen Neuroscience Program,  2014 - 2015,  $231,018.
  • Progressing the clinical neuropsychological phenotype of Alzheimer's disease.,  Florey Institute of Neuroscience and Mental Health,  Grant,  2014 - 2015,  $107,935.
  • A study of the kinetics of biomarkers and their presumptive relationship with brain amyloid ,  Commonwealth Scientific and Industrial Research Organisation (CSIRO),  Araclon Biotech ,  2014 - 2015,  $132,200.
  • Effects of Latrepirdine on beta amyloid clearance, aggregation and neurodegeneration in Alzheimer?s disease,  McCusker Alzheimer's Research Foundation Inc,  McCusker Alzheimer's Research Foundation - Sponsorship,  2014 - 2015,  $12,555.
  • A Pilot Clinical Study to Evaluate the Potential of AMLAMAXa?? (Emblica Officinalis) Extract on Raising HDL-Cholesterol Levels and Decreasing Plasma Amyloid beta (A??) Levels in a Perth Memory,  Hollywood Private Hospital Research Foundation,  Grant,  2010 - 2014,  $14,760.
  • Investigation of Biomarkers of Disease State in Alzheimer's Disease and Non-AD Dementias,  Commonwealth Scientific and Industrial Research Organisation (CSIRO),  Merck Sharp and Dohme Corpe Grant,  2011 - 2014,  $265,000.
  • AIBL Carer Extension Study (ACES),  Florey Institute of Neuroscience and Mental Health,  Wyeth Caregiver Study,  2013 - 2014,  $87,840.
  • The Australian Imaging, Biomarker and Lifestyle Study of Ageing - Round 2,  Commonwealth Scientific and Industrial Research Organisation (CSIRO),  Science Industry Endowment Fund Agreement,  2010 - 2013,  $5,341,586.
  • Evaluation of the protective benefit of leisure-time physical activity for the prevention of Alzheimer's disease in older adults,  Edith Cowan University,  ECU Early Career Researcher - Grant,  2010 - 2012,  $24,750.

Recent Publications (within the last five years)

Journal Articles

  • Goozee, K., Shah, T., Sohrabi, H., Rainey-Smith, S., Brown, B., Verdile, G., Martins, R., (2015), Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease. British Journal of Nutrition, 115(3), 449-465, Cambridge, United Kingdom, DOI: 10.1017/S0007114515004687.
  • Gardener, S., Rainey-Smith, S., Martins, R., (2015), Diet and Inflammation in Alzheimer's Disease and Related Chronic Diseases: A Review. Journal of Alzheimer's disease, 50(2016), 301-334, Netherlands, DOI: 10.3233/JAD-150765.
  • Gardener, S., Rainey-Smith, S., Macaulay, SL., Taddei, K., Rembach, A., Maruff, P., Ellis, K., Masters, C., Rowe, C., Ames, D., Keogh, J., Martins, R., Aibl Group, T., (2015), Comparative analysis of the Cancer Council of Victoria and the online Commonwealth Scientific and Industrial Research Organisation FFQ. British Journal of Nutrition, 114(10), 1683-1693, Cambridge, United Kingdom, DOI: 10.1017/S0007114515003335.
  • Gupta, V., Wilson, A., Burnham, S., Hone, E., Pedrini, S., Laws, S., Lim, F., Rembach, A., Rainey-Smith, S., Ames, D., Cobiac, L., Macaulay, SL., Masters, C., Rowe, C., Bush, A., Martins, R., (2015), Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort. Alzheimer's Research and Therapy, 7(1), Article no.16, United Kingdom, DOI: 10.1186/s13195-015-0105-6.
  • Rembach, A., Evered, L., Li, Q., Nash, T., Vidaurre, L., Fowler, CJ., Pertile, KK., Rumble, RL., Trounson, BO., Maher, S., Mooney, F., Farrow, M., Taddei, K., Rainey-Smith, S., Laws, S., Macaulay, SL., Wilson, W., Darby, DG., Martins, R., Ames, D., Collins, S., Silbert, B., Masters, CL., Doecke, JD., Aibl Research Group, .., (2015), Alzheimer's Disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology. Alzheimer's Research and Therapy, 7(2015), Article number 71, London, United Kingdom, DOI: 10.1186/s13195-015-0157-7.
  • Li, Q., Villemagne, V., Doecke, J., Rembach, A., Sarros, S., Varghese, S., McGlade, A., Laughton, K., Pertile, K., Fowler, C., Rumble, R., Trounson, B., Taddei, K., Rainey-Smith, S., Laws, S., Robertson, J., Evered, L., Silbert, B., Ellis, K., Rowe, C., Macaulay, S., Darby, D., Martins, R., Ames, D., Masters, C., Collins, S., (2015), Alzheimer?s Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-? Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Journal of Alzheimer's Disease, 48(1), 175-187, Amsterdam, Netherlands, DOI: 10.3233/JAD-150247.
  • Buckley, RF., Ellis, KA., Ames, D., Rowe, CC., Lautenschlager, NT., Maruff, P., Villemagne, V., Macaulay, SL., Szoeke, C., Martins, R., Masters, CL., Savage, G., Rainey-Smith, S., Rembach, A., Saling, MM., Aibl Research Group, .., (2015), Phenomenological characterization of memory complaints in preclinical and prodromal Alzheimer's disease. Neuropsychology, 29(4), 571-581, Washington DC, United States, DOI: 10.1037/neu0000156.
  • Creegan, R., Hunt, W., McManus, A., Rainey-Smith, S., (2015), Diet, nutrients and metabolism: cogs in the wheel driving Alzheimer?s disease pathology?. British Journal of Nutrition, 113(10), 1499-1517, Cambridge, United Kingdom, DOI: 10.1017/S0007114515000926.
  • Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, DOI: 10.3389/fnagi.2015.00016.
  • Sutton, T., Sohrabi, H., Rainey-Smith, S., Bird, S., Weinborn, M., Martins, R., (2015), The role of APOE-?4 and beta amyloid in the differential rate of recovery from ECT: a review. Translational Psychiatry, 5(e539), 1-8, London, UK, DOI: 10.1038/tp.2015.39.
  • Buckley, R., Ellis, K., Ames, D., Rowe, C., Lautenschlager, N., Maruff, P., Villemagne, V., Macauley, L., Szoeke, C., Martins, R., Masters, C., Savage, G., Rainey-Smith, S., Rembach, A., Saling, M., (2015), Phenomenological characterisation of memory complaints in preclinical and prodromal Alzheimer's disease. Neuropsychology, 29(4), 571-581, United States, DOI: 10.1037/neu0000156.
  • Thai, C., Lim, YY., Villemagne, VL., Laws, S., Ames, D., Ellis, KA., Rainey-Smith, S., Martins, R., Masters, CL., Rowe, CC., Maruff, P., Aibl Research Group, .., (2015), Amyloid-Related Memory Decline in Preclinical Alzheimer?s Disease is Dependent on APOE ?4 and is Detectable over 18-Months. PLoS One, 10(10), Article number e0139082, San Francisco, California, United States, DOI: 10.1371/journal.pone.0139082.
  • Ellis, K., Szoeke, C., Bush, A., Darby, D., Graham, P., Lautenschlager, N., Macaulay, L., Martins, R., Maruff, P., Masters, C., McBride, S., Pike, K., Rainey-Smith, S., Rembach, A., Robertson, J., Rowe, C., Savage, G., Villemagne, V., Woodward, M., Wilson, W., Zhang, P., Ames, D., Aibl Research Group, T., (2014), Rates of diagnostic transition and cognitive change at 18-month follow-up among 1,112 participants in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL). International Psychogeriatrics, 26(4), 543-554, DOI: 10.1017/S1041610213001956.
  • Gardener, S., Rainey-Smith, S., Barnes, M., Sohrabi, H., Weinborn, M., Lim, Y., Harrington, K., Taddei, K., Gu, Y., Rembach, A., Szoeke, C., Ellis, K., Masters, C., Macaulay, S., Rowe, C., Ames, D., Keogh, J., Scarmeas, N., Martins, R., For the Aibl, RG., (2014), Dietary patterns and cognitive decline in an Australian study of ageing. Molecular Psychiatry, online(online), online, United Kingdom.
  • Brown, B., Bourgeat, P., Peiffer, J., Burnham, S., Laws, S., Rainey-Smith, S., Bartres-Faz, D., Villemagne, V., Taddei, K., Rembach, A., Bush, A., Ellis, K., Macaulay, SL., Rowe, C., Ames, D., Masters, C., Maruff, P., Martins, R., (2014), Influence of BDNF Val66Met on the relationship between physical activity and brain volume. Neurology, 83(15), 1345-52, DOI: 10.1212/WNL.0000000000000867.
  • Villemagne, V., Dore, V., Yates, P., Brown, B., Mulligan, R., Bourgeat, P., Veljanoski, R., Rainey-Smith, S., Ong, K., Rembach, A., Williams, R., Burnham, S., Laws, S., Salvado, O., Taddei, K., Macaulay, SL., Martins, R., Ames, D., Masters, C., Rowe, C., (2014), En Attendant Centiloid. Advances in Research, 2(12), 723-729, Online, DOI: 10.9734/AIR/2014/11599.
  • Rembach, A., Watt, A., Wilson, W., Rainey-Smith, S., Ellis, K., Rowe, C., Villemagne, V., Macaulay, S., Bush, A., Martins, R., Ames, D., Masters, C., Doecke, J., Aibl Research Group, T., (2014), An increased neutrophil-lymphocyte ratio in Alzheimer?s disease is a function of age and is weakly correlated with neocortical amyloid accumulation. Journal of Neuroimmunology, 273(1-2), 65-71, DOI: 10.1016/j.jneuroim.2014.05.005.
  • Buckley, R., Saling, M., Irish, M., Ames, D., Rowe, C., Lautenschlager, N., Maruff, P., Macaulay, SL., Martins, R., Masters, C., Rainey-Smith, S., Rembach, A., Savage, G., Szoeke, C., Ellis, K., (2014), Personal memory function in mild cognitive impairment and subjective memory complaints: Results from the Australian Imaging, Biomarkers, and Lifestyle (AIBL) study of ageing. Journal of Alzheimer's Disease, 40(3), 551-561 , Netherlands, DOI: 10.3233/JAD-131820.
  • Rembach, A., Faux, N., Watt, A., Pertile, K., Rumble, R., Trounson, B., Fowler, C., Roberts, B., Perez, K., Li, Q., Laws, S., Taddei, K., Rainey-Smith, S., Robertson, J., Vandijck, M., Vanderstichele, H., Barnham, K., Ellis, K., Szoeke, C., Macaulay, L., Rowe, C., Villemagne, V., Ames, D., Martins, R., Bush, A., Masters, C., Aibl Research Group, T., (2014), Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's and Dementia, 10(1), 53-61, United States, DOI: 10.1016/j.jalz.2012.12.006.
  • Buckley, R., Saling, M., Irish, M., Ames, D., Rowe, C., Villemagne, V., Lautenschlager, N., Maruff, P., Macaulay, L., Martins, R., Szoeke, C., Masters, C., Rainey-Smith, S., Rembach, A., Savage, G., Ellis, K., Aibl Research Group, T., (2014), Autobiographical narratives relate to Alzheimer?s disease biomarkers in older adults. International Psychogeriatrics, 26(10), 1737-1746, DOI: 10.1017/S1041610214001136.
  • Frost, S., Kanagasingam, Y., Sohrabi, H., Vignarajan, J., Bourgeat, P., Salvado, O., Villemagne, V., Rowe, C., Macaulay, L., Szoeke, C., Ellis, K., Ames, D., Masters, C., Rainey-Smith, S., Martins, R., (2013), Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease. Translational Psychiatry, 3(February), 1-8, United Kingdom.
  • Gardener, S., Rainey-Smith, S., Keogh, J., Mathieson, S., Martins, R., (2013), Dietary Patterns Associated with Alzheimer's Disease and Related Chronic Disease Risk: A Review. Alzheimer's Disease & Parkinsonism, Special(2013), online, online.
  • Carrillo, M., Rowe, C., Szoeke, C., Masters, C., Ames, D., O'Meara, T., Macaulay, SL., Milner, A., Ellis, K., Maruff, P., Rainey-Smith, S., Martins, R., Bain, L., Head, R., (2013), Research and standardization in Alzheimer's trials: Reaching international consensus. Alzheimer's and Dementia, 9(2), 160-168, United States, DOI: 10.1016/j.jalz.2012.10.006.
  • Frost, S., Kanagasingam, Y., Sohrabi, H., Bourgeat, P., Villemagne, V., Rowe, C., Macaulay, SL., Szoeke, C., Ellis, K., Ames, D., Masters, C., Rainey-Smith, S., Martins, R., (2013), Pupil Response Biomarkers for Early Detection and Monitoring of Alzheimer's Disease. Current Alzheimer Research, 10(9), 931-939.
  • Ellis, KA., Rainey-Smith, S., Rembach, A., Macaulay, SL., Villemagne, VL., (2013), Enabling a multidisciplinary approach to the study of ageing and Alzheimer's disease: An update from the Australian Imaging Biomarkers and Lifestyle (AIBL) study. International Review of Psychiatry, 25(6), 699-710, United Kingdom, DOI: 10.3109/09540261.2013.870136.
  • Gardener, S., Gu, Y., Rainey-Smith, S., Keogh, JB., Clifton, PM., Mathieson, SL., Taddei, K., Mondal, A., Ward, V., Scarmeas, N., Barnes, M., Ellis, K., Head, R., Masters, C0., Ames, D., Macaulay, S0., Rowe, C0., Szoeke, C., Martins, R., (2012), Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population. Translational Psychiatry, 2(2012), e164, DOI: 10.1038/tp.2012.91.
  • Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, L., Szoeke, C., Rowe, C., Martins, R., (2012), Physical activity and amyloid-? plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18(8), 875-881, United Kingdom.
  • Brown, B., Peiffer, J., Sohrabi, H., Mondal, A., Gupta, V., Rainey-Smith, S., Taddei, K., Burnham, S., Ellis, K., Szoeke, C., Masters, CL., Ames, D., Rowe, C., Martins, R., (2012), Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2(2012), art. no. e191 , DOI: 10.1038/tp.2012.118.

Research Student Supervision

Associate Supervisor

  • Doctor of Philosophy,  Impact Of Nutrition On Cognition And Its Association With Blood And Brain Alzheimer Disease Related Biomarkers
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