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Dr Veer Gupta

Research Fellow

Contact Information Telephone: (61 8) 6304 5838, Email: v.gupta@ecu.edu.au, Campus: Joondalup, Room: JO17.107
Staff Member Details
Telephone: (61 8)  6304 5838  
Email: v.gupta@ecu.edu.au   
Campus: Joondalup  
Room: JO17.107  

 

Staff Qualifications

  • PhD (Doctoral Degree), India, 2009 .
  • M (Master Degree), India, 2002 .
  • B (Bachelor Degree), India, 2001 .

Research

Recent Research Grants

  • 4.4B1 Novel Therapeutics for AD Testosterone Trial,  CRC For Mental Illness,  CRC Grant,  2010 - 2016,  $601,938.
  • Establishing a combined ocular and blood biomarker panel for Alzheimer?s disease.,  Australian National University,  ANU - Dementia CRC - Grant,  2014 - 2015,  $517,977.
  • Discovery and Validation of Alzheimer's disease biomarkers in human plasma,  National Health and Medical Research Council,  Project Grants,  2011 - 2013,  $352,524.
  • An innovative approach to identify specific biomarkers for early diagnosis of Alzheimer's disease,  Australian National University,  ANU - Dementia CRC - Grant,  2013 - 2014,  $115,000.
  • Nuclear magnetic resonance spectroscopy facilities ? Advancing cutting-edge chemical, biological, energy and materials research in Western Australia,  Australian Research Council,  Grant - Linkage (Infrastructure),  2014,  $1,666,000.
  • Initiating an Indo-Australian cooperation for early diagnosis and prediction in the aged population: Partnering the universities for a tactical approach to Alzheimer's disease and other neurodegenerative conditions,  Department of Foreign Affairs and Trade,  Australia-India Council,  2011 - 2012,  $4,000.
  • The Australian Imaging, Biomarker and Lifestyle Study of Ageing - Round 2,  Commonwealth Scientific and Industrial Research Organisation,  Science Industry Endowment Fund Agreement,  2010 - 2013,  $5,008,586.
  • Investigating the Association Between APOE Promoter Polymorphisms and Plasma APOE levels: A Blood Test for Alzheimera??s Disease.,  Edith Cowan University,  ECU Early Career Researcher - Grant,  2009 - 2010,  $24,830.

Recent Publications (within the last five years)

Books

  • Gupta, V., Gupta, V., (2012), Alpha-1 Proteinase Inhibitor in Action: Roles and Mechanistic Insights: Structure Function Relationship of Alpha-1 Proteinase Inhibitor., 200, Europe.
  • Gupta, V., Gupta, V., (2012), Molecular Mechanisms and Therapeutic Strategies in Alzheimer's Disease., 240, Europe.

Journal Articles

  • Gupta, V., Monica, F., Berrocal, R., Rao, KS., Rao, K., (2013), Studies on the mechanism of the DNA nicking property of amyloid-?40: implications in Alzheimer's disease. Journal of Alzheimer's Disease, 33(4), 1059-1071, Netherlands, DOI: 10.3233/JAD-121249.
  • Steele, J., Su, J., Lachenmayer, L., Liken, J., Stock, A., Kim, S., Delgado, L., Alfaro, I., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S., (2013), Latrepirdine stimulates autophagy and reduces accumulation of a-synuclein in cells and in mouse brain. Molecular Psychiatry, 18(8), 882-888, United Kingdom, DOI: 10.1038/mp.2012.115.
  • Gupta, V., Gupta, V., Martins, R., (2013), Semagacestat for treatment of Alzheimer?s disease. New England Journal of Medicine, 369(17), 1660-1661, DOI: 10.1056/NEJMc1310231.
  • Gupta, V., Sundaram, R., Martins, R., (2013), Multiplex biomarkers in blood. Alzheimer's Research & Therapy, 5(3), Article 31, United Kingdom, DOI: 10.1186/alzrt185.
  • O' Bryant, S., Xiao, G., Edwards, M., Devous, M., Gupta, V., Martins, R., Zhang, F., Barber, R., (2013), Biomarkers of Alzheimer?s Disease Among Mexican Americans. Journal of Alzheimer's Disease, 34(4), 841-849, Netherlands, DOI: 10.3233/JAD-122074.
  • Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoeke, C., Taddei, K., Villemagne, V., Martins, R., (2012), Associations between gonadotropins, testosterone and ? amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry, 19(1), 69-75, United Kingdom, DOI: 10.1038/mp.2012.147.
  • Steele, JW., Ju, S., Lachenmayer, M., Liken, J., Stock, A., Kim, SH., Delgado, L., Alfaro, I., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S., (2012), Latrepiridine stimulates autophagy and reduces accumulation of alpha-synuclein in cells and in mouse brain. Molecular Psychiatry, 18(August 2013), 882-888, United Kingdom, DOI: 10.1038/mp.2012.115.
  • Brown, B., Peiffer, J., Sohrabi, H., Mondal, A., Gupta, V., Rainey-Smith, S., Taddei, K., Burnham, S., Ellis, K., Szoeke, C., Masters, CL., Ames, D., Rowe, C., Martins, R., (2012), Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2(2012), art. no. e191 , DOI: 10.1038/tp.2012.118.
  • Bharadwaj, P., Verdile, G., Barr, R., Gupta, V., Steele, J., Lachenmayer, L., Yue, Z., Ehrlich, M., Petsko, G., Ju, S., Ringe, D., Sankovich, S., Caine, J., Macreadie, I., Gandy, S., Martins, R., (2012), Latrepirdine (Dimebon?) enhances autophagy and reduces intracellular GFP-A?42 levels in yeast. Journal of Alzheimer's disease, 32(4), 949-967, Netherlands, DOI: 10.3233/JAD-2012-120178.
  • Steele, JW., Lachenmayer, ML., Ju, S., Stock, A., Liken, J., Kim, SH., Delgado, LM., Alfaro, IE., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Fraser, P., Westaway, D., St George-Hyslop, P0., Szabo, P., Relkin, N0., Buxbaum, J0., Glabe, C0., Protter, A0., Martins, R., Ehrlich, M0., Petsko, G0., (2012), Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry, 1-9, United Kingdom, DOI: 10.1038/mp.2012.106.
  • Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, L., Szoeke, C., Rowe, C., Martins, R., (2012), Physical activity and amyloid-? plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18(8), 875-881, United Kingdom.
  • Doecke, J., Laws, S., Faux, N., Wilson, W., Burnham, S., Lam, P., Mondal, A., Bedo, J., Bush, A., Brown, B., De Ruyck, K., Ellis, K., Fowler, C., Gupta, V., Head, R., Macaulay, SL., Pertile, K., Rowe, C., Rembach, A., Rodrigues, M., Rumble, R., Szoeke, C., Taddei, K., Taddei, T., Trounson, B., Ames, D., Masters, C., Martins, R., (2012), Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease. Archives of Neurology, 69(10), 1318-1325, United States, DOI: 10.1001/archneurol.2012.1282.
  • Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoecke, C., Taddei, K., Villemagne, V., Martins, R., (2012), Associations between gonadotropins, testosterone and ? amyloid in men at risk of Alzheimer?s disease. Molecular Psychiatry, 7, United Kingdom, DOI: 10.1038/mp.2012.147.
  • Gupta, V., Laws, S., Villemagne, V., Ames, D., Bush, A., Ellis, K., Lui, J., Masters, C., Rowe, C., Szoeke, C., Taddei, K., Martins, R., (2011), Plasma apolipoprotein e and Alzheimer disease risk: The AIBL study of aging. Neurology, 76(12), 1091-1098, DOI: 10.1212/WNL.0b013e318211c352.
  • Lui, J., Laws, S., Li, Q., Villemagne, V., Ames, D., Brown, B., Bush, A., De Ruyck, K., Dromey, J., Ellis, K., Faux, N., Foster, J., Fowler, C., Gupta, V., Hudson, P., Laughton, K., Masters, C., Pertile, K., Rembach, A., Rimajova, M., Rodrigues, M., Rowe, C., Rumble, R., Szoecke, C., Taddei, K., Taddei, T., Trounson, B., Ward, V., Martins, R., (2010), Plasma amyloid-? as a biomarker in Alzheimer?s disease: the AIBL study of aging. Journal of Alzheimer's Disease, 20(4), 1233-1242, Netherlands, DOI: 10.3233/JAD-2010-090249.
  • Gupta, V., Indi, SS., Rao, KS., (2009), Garlic Extract Exhibits Antiamyloidogenic Activity on Amyloid-beta Fibrillogenesis: Relevance to Alzheimer?s Disease. Phytotherapy Research, 23(1), 111-115, United Kingdom, DOI: 10.1002/ptr.2574.

Research Student Supervision

Associate Supervisor

  • Master of Science (Human Biology),  Plasma Insulin-degrading Enzyme: Characterisation And Evaluation As A Potential Biomarker For Alzheimer's Disease..
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