Dr Anna Callan

Research Fellow

Telephone: (61 8)  6304 2349  
Email: a.callan@ecu.edu.au   
Campus: Joondalup  
Room: JO19.346  

 

Current Teaching

  • Lab demonstrator for units SCB2222 and SCB3322

Background

  • 2009-present: Postdoctoral Research Fellow, Edith Cowan University
  • 2008-2009: Research Officer, Telethon Institute for Child Health Research
  • 2006-2007: Postdoctoral Research Associate Faculty of Life Sciences, University of Manchester

Research Areas and Interests

Human Exposure to Environmental Contaminants and Associated Health Effects

  • Exposure of susceptible groups, such as children, to persistent toxic substances and the resulting effects of exposure
  • Assessment of the contribution of dietary exposure to persistent toxic substances to an individual’s total level of exposure.
  • Monitoring the biological effects of persistent toxic substance exposure as determined by the measurement of biomarkers of disease, oxidative damage and DNA modifications

I obtained my PhD in Biochemistry/Cell Biology however the focus of my research has changed recently and I am now involved in a number of projects relating to environmental exposures and their health effects. I am currently involved in a number of research projects which include investigating the exposure of pregnant women to a range of environmental contaminants (metals, pesticides and persistent organic compounds) and children’s exposure to metals, emerging pollutants and particulate matter.

However, my background in biological sciences means that I am keen to explore ways of investigating not just personal exposure to environmental contaminants, but also the health effects of exposure and the biological mechanisms underlying those effects. I am particularly interested in environmental contaminants relating to health outcomes in susceptible population groups such as young children and the elderly. The effect of pre-natal exposure to environmental contaminants on pregnancy and birth outcomes is also an area of considerable interest to me. In addition I am keen to explore the contribution of dietary exposure of metals and pollutants to an individual’s total exposure.

  • Environment exposure
  • Biological effects of exposure to environmental contaminants
  • Contribution of diet to exposure to metals and other contaminants

Staff Qualifications

  • Doctor of Philosophy, England, 2006 .
  • Master, England, 2002 .
  • Bachelor of Science, England, 2001 .

Research

Recent Research Grants

  • Particulates, Metals and Human Exposure,  Telethon Institute for Child Health Research,  Grant,  2009,  $29,794.

Recent Publications (within the last five years)

Journal Articles

  • Callan, A., Winters, M., Barton, C., Boyce, M., Hinwood, A., (2011), Children's Exposure to Metals: A Community-Initiated Study. Archives of Environmental Contamination and Toxicology, N/A(N/A), N/A, DOI: 10.1007/s00244-011-9727-2.
  • Callan, A., Hinwood, A., (2011), Exposures to lead. Reviews on Environmental Health, 26(1), 13-15, DOI: 10.1515/REVEH.2011.003.
  • Callan, A., Milne, E., (2009), Involvement of the IGF system in fetal growth and childhood cancer: an overview of potential mechanisms. Cancer Causes and Control, 20(10), 1783-1798, The Netherlands, DOI: 10.1007/s10552-009-9378-z.
  • Cross, B., McKibbin, C., Callan, A., Roboti, P., Piacenti, M., Rabu, C., Wilson, C., Whitehead, R., Flitsch, S., Pool, M., High, S., Swanton, E., (2009), Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum. Journal of Cell Science, 122(23), 4393-4400, United Kingdom, DOI: 10.1242/jcs.054494.
  • Callan, A., Bunning, S., Jones, O., High, S., Swanton, E., (2007), Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulum. Biochemical Journal, 401(2), 607-612 , United Kingdom, DOI: 10.1042/BJ20061313.