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Dr Ashleigh McEvoy

Ashleigh is a Postdoctoral Research Fellow and clinical coordinator within the School of Medical and Health Sciences.

Qualifications

  • Doctor of Philosophy, Edith Cowan University, 2018.
  • Master of Science Human Biology, Edith Cowan University, 2014.
  • Bachelor of Science, Edith Cowan University, 2012.

Research Outputs

Journal Articles

  • Aya-Bonilla, C., Morici, M., Hong, X., McEvoy, A., Sullivan, R., Freeman, J., Calapre, L., Khattak, M., Meniawy, T., Millward, M., Ziman, M., Gray, E. (2020). Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells. British Journal of Cancer, 122(7), 1059-1067. https://doi.org/10.1038/s41416-020-0750-9.
  • Marsavela, G., Lee, J., Calapre, L., Wong, S., Pereira, M., McEvoy, A., Reid, A., Robinson, C., Warburton, L., Abed, A., Khattak, M., Meniawy, T., Dawson, S., Sandhu, S., Carlino, M., Menzies, A., Scolyer, R., Long, G., Amanuel, B., Millward, M., Ziman, M., Rizos, H., Gray, E. (2020). Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who May Benefit from Combination Immunotherapy. Clinical Cancer Research, 26(22), 5926-5933. https://doi.org/10.1158/1078-0432.CCR-20-2251.
  • Clark, M., Rizos, H., Pereira, M., McEvoy, A., Marsavela, G., Calapre, L., Meehan, K., Ruhen, O., Khattak, M., Meniawy, T., Long, G., Carlino, M., Menzies, A., Millward, M., Ziman, M., Gray, E. (2020). Detection of BRAF splicing variants in plasma-derived cell-free nucleic acids and extracellular vesicles of melanoma patients failing targeted therapy therapies. Oncotarget, 11(44), 4016-4027. https://doi.org/https://doi.org/10.18632/oncotarget.27790.
  • Lee, J., Menzies, A., Carlino, M., McEvoy, A., Sandhu, S., Weppler, A., Diefenbach, R., Dawson, S., Kefford, R., Millward, M., Al-Ogaili, Z., Tra, T., Gray, E., Wong, S., Scolyer, R., Long, G., Rizos, H. (2020). Longitudinal monitoring of ctDNA in patients with melanoma and brain metastases treated with immune checkpoint inhibitors. Clinical Cancer Research, 26(15), 4064-4071. https://doi.org/10.1158/1078-0432.CCR-19-3926.
  • Khattak, M., Abed, A., Reid, A., McEvoy, A., Millward, M., Ziman, M., Gray, E. (2020). Role of Serum Vascular Endothelial Growth Factor (VEGF) as a Potential Biomarker of Response to Immune Checkpoint Inhibitor Therapy in Advanced Melanoma: Results of a Pilot Study. Frontiers in Oncology, 10(30 June 2020), Article number 1041. https://doi.org/10.3389/fonc.2020.01041.
  • Warburton, L., Meniawy, T., Calapre, L., Pereira, M., McEvoy, A., Ziman, M., Gray, E., Millward, M. (2020). Stopping targeted therapy for complete responders in advanced BRAF mutant melanoma. Scientific Reports, 10(1), Article number 18878. https://doi.org/10.1038/s41598-020-75837-5.
  • Khattak, M., Reid, A., Freeman, J., Pereira, M., McEvoy, A., Lo, J., Frank, M., Meniawy, T., Didan, A., Spencer, I., Amanuel, B., Millward, M., Ziman, M., Gray, E. (2020). PD-L1 Expression on Circulating Tumor Cells May Be Predictive of Response to Pembrolizumab in Advanced Melanoma: Results from a Pilot Study. The Oncologist, 25(3), e520-e527. https://doi.org/10.1634/theoncologist.2019-0557.
  • Marsavela, G., Johansson, P., Pereira, M., McEvoy, A., Reid, A., Robinson, C., Warburton, L., Khattak, M., Meniawy, T., Amanuel, B., Millward, M., Hayward, N., Ziman, M., Gray, E., Calapre, L. (2020). The Prognostic Impact of Circulating Tumour DNA in Melanoma Patients Treated with Systemic Therapies-Beyond BRAF Mutant Detection. Cancers, 12(12), Article number 3793. https://doi.org/10.3390/cancers12123793.

Journal Articles

  • McEvoy, A., Pereira, M., Reid, A., Pearce, R., Cowell, L., Al-Ogaili, Z., Khattak, M., Millward, M., Meniawy, T., Gray, E., Ziman, M. (2019). Monitoring melanoma recurrence with circulating tumor DNA: a proof of concept from three case studies. Oncotarget, 10(2), 113-122. https://doi.org/10.18632/oncotarget.26451.
  • Calapre, L., Giardina, T., Robinson, C., Reid, A., Al-Ogaili, Z., Pereira, M., McEvoy, A., Warburton, L., Hayward, N., Khattak, M., Meniawy, T., Millward, M., Amanuel, B., Ziman, M., Gray, E. (2019). Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma. Molecular Oncology, 13(2), 171-184. https://doi.org/10.1002/1878-0261.12391.
  • Stark, M., Gray, E., Isaacs, T., Chen, F., Millward, M., McEvoy, A., Zaenker, P., Ziman, M., Soyer, H., Glasson, W., Warrier, S., Stark, A., Rolfe, O., Palmer, J., Hayward, N. (2019). A Panel of Circulating MicroRNAs Detects Uveal Melanoma With High Precision. Translational Vision Science and Technology, 8(6), Article 12. https://doi.org/10.1167/tvst.8.6.12.

Journal Articles

  • McEvoy, A., Wood, B., Ardakani, N., Pereira, M., Pearce, R., Cowell, L., Robinson, C., Grieu-Iacopetta, F., Spicer, A., Amanuel, B., Ziman, M., Gray, E. (2018). Droplet Digital PCR for Mutation Detection in Formalin-Fixed, Paraffin-Embedded Melanoma Tissues: A Comparison with Sanger Sequencing and Pyrosequencing. The Journal of Molecular Diagnostics, 20(2), 240-252. https://doi.org/10.1016/j.jmoldx.2017.11.009.
  • McEvoy, A., Warburton, L., Al-Ogaili, Z., Celliers, L., Calapre, L., Pereira, M., Khattak, M., Meniawy, T., Millward, M., Ziman, M., Gray, E. (2018). Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients. BMC Cancer, 18(1), Article no. 726. https://doi.org/10.1186/s12885-018-4637-6.

Journal Articles

  • McEvoy, A., Calapre, L., Pereira, M., Giardina, T., Robinson, C., Khattak, M., Meniawy, T., Pritchard, A., Hayward, N., Amanuel, B., Millward, M., Ziman, M., Gray, E. (2017). Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma. Oncotarget, 8(45), 78890-78900. https://doi.org/10.18632/oncotarget.20354.

Journal Articles

  • McEvoy, A., Roberts, P., Yap, K., Matson, P. (2014). Development of a simplified method of human semen storage for the testing of sperm DNA fragmentation using the Halosperm G2 test kit. Fertility and Sterility, 102(4), 981-988. https://doi.org/10.1016/j.fertnstert.2014.07.737.
  • Sim, M., McEvoy, A., Wain, T., Khong, E. (2014). Improving health professional's knowledge of hepatitis B using cartoon based learning tools: a retrospective analysis of pre and post tests. BMC Medical Education, 14(online), Article no. 244. https://doi.org/10.1186/s12909-014-0244-7.

Conference Publications

  • Sim, M., Khong, E., McEvoy, A., Wain, T., Sim, M., Williams, T. (2013). Cartoons for e-health informatics. Proceedings of the 2nd Australian eHealth Informatics and Security Conference (50-57). Security Research Centre, Edith Cowan University.

Research Projects

  • Circulating Melanoma Cells as Predictive Biomarkers of Response to Immune Checkpoint Blockade , Cancer Council of WA Inc, Grant, 2020 ‑ 2022, $100,000.
  • Detection of circulating tumour DNA for identification of Stage III metastatic melanoma patients , Edith Cowan University, ECU Early Career Researcher Grant - 2019, 2019 ‑ 2020, $29,960.
  • Translation of "Liquid Biopsy" Research into Clinical Practice, Western Australian Health Translation Network, Early Career Fellowships, 2019 ‑ 2020, $121,074.
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