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Dr Belinda Brown

Belinda is a Research Fellow in Neuroscience based at the McCusker Foundation.

Qualifications

  • Doctor of Philosophy, The University of Western Australia, 2014.
  • Bachelor of Science (Molecular Biotechnology), Curtin University of Technology, 2007.

Research

Recent Research Grants

  • The role of intense physical activity in protecting the ageing brain,  National Health and Medical Research Council,  Dementia Research Development Fellowship,  2016 - 2020,  $778,579.
  • The effect of high-intensity exercise on Alzheimer’s disease-related gene expression,  Brain Foundation,  Research Gifts Program,  2017,  $39,875.
  • Application for travel to the Brain Aging and Cognitive Health Laboratory at the University of Pittsburgh,  Dementia Australia Research Foundation,  AADRF - Rosemary Foundation Travel Fellowship,  2015 - 2016,  $15,000.
  • Exercise intensity and prevention of cognitive decline in older adults,  Edith Cowan University,  ECU Early Career Researcher Grant - 2015,  2015 - 2016,  $24,066.
  • The influence of exercise intensity on the prevention of cognitive decline in older adults,  Dementia Australia Research Foundation,  AADRF - Postdoctoral Fellowships,  2014 - 2016,  $238,034.

Recent Publications (within the last five years)

Journal Articles

  • Fine, L., Weinborn, M., Ng, A., Loft, S., Li, Y., Hodgson, E., Parker, D., Rainey-Smith, S., Sohrabi, H., Brown, B., Martins, R., Bucks, R., (2019), Sleep disruption explains age-related prospective memory deficits: implications for cognitive aging and intervention. Aging, Neuropsychology and Cognition: A Journal on Normal and Dysfunctional Development, 26(4), 621-636, Routledge, DOI: 10.1080/13825585.2018.1513449.
  • Marston, K., Brown, B., Rainey-Smith, S., Bird, S., Wijaya, L., Teo, S., Laws, S., Martins, R., Peiffer, J., (2019), Twelve weeks of resistance training does not influence peripheral levels of neurotrophic growth factors or homocysteine in healthy adults: a randomized‑controlled trial. European Journal of Applied Physiology, 119(10), 2167-2176, Germany, Springer, DOI: 10.1007/s00421-019-04202-w.
  • Sohrabi, H., Weinborn, M., Laske, C., Bates, K., Christensen, D., Taddei, K., Rainey-Smith, S., Brown, B., Gardener, S., Laws, S., Martins, G., Burnham, S., Bucks, R., Reisberg, B., Lautenschlager, N., Foster, J., Martins, R., (2019), Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study. International Psychogeriatrics, 31(4), 513-525, Cambridge University Press, DOI: 10.1017/S1041610218001072.
  • Marston, K., Peiffer, J., Rainey-Smith, S., Gordon, N., Teo, S., Laws, S., Sohrabi, H., Martins, R., Brown, B., (2019), Resistance training enhances delayed memory in healthy middle-aged and older adults: A randomised controlled trial. Journal of Science and Medicine in Sport, 22(11), 1226-1231, DOI: 10.1016/j.jsams.2019.06.013.
  • Fernando, B., Rainey-Smith, S., Gardener, S., Villemagne, V., Burnham, S., Macaulay, SL., Brown, B., Gupta, V., Sohrabi, H., Weinborn, M., Taddei, K., Laws, S., Goozee, K., Ames, D., Fowler, C., Maruff, P., Masters, C., Salvado, O., Rowe, C., Martins, R., (2018), Associations of dietary protein and fiber intake with brain and blood amyloid-B. Journal of Alzheimer's Disease, 61(2018), 1589-1598, Netherlands, IOS Press, DOI: 10.3233/JAD-170742.
  • Weinborn, M., Bucks, R., Sohrabi, H., Rainey-Smith, S., Brown, B., Gardener, S., Gozt, O., Christensen, D., Savage, G., Laws, S., Taddei, K., Maruff, P., Robertson, J., Ellis, K., Ames, D., Masters, C., Rowe, C., Martins, R., (2018), Trajectories of Irregular Word Reading Ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study. Psychological Assessment, 30(10), 1308-1316, United States, American Psychological Association, DOI: 10.1037/pas0000565.
  • Rainey-Smith, S., Mazzucchelli, G., Villemagne, V., Brown, B., Porter, T., Weinborn, M., Bucks, R., Milicic, L., Sohrabi, H., Taddei, K., Ames, D., Maruff, P., Masters, C., Rowe, C., Salvado, O., Martins, R., Laws, S., (2018), Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden. Translational Psychiatry, 8(1), Article no. 47, United Kingdom, Nature Publishing Group, DOI: 10.1038/s41398-018-0094-x.
  • McCabe, K., Woods, S., Weinborn, M., Sohrabi, H., Rainey-Smith, S., Brown, B., Gardener, S., Taddei, K., Martins, R., (2018), Personality characteristics are independently associated with prospective memory in the laboratory, and in daily Life, among older adults. Journal of Research in Personality, 76(Oct 2018), 32-37, United States, Academic Press, DOI: 10.1016/j.jrp.2018.06.006.
  • Martins, R., Villemagne, V., Sohrabi, H., Chatterjee, P., Shah, T., Verdile, G., Fraser, P., Taddei, K., Gupta, V., Rainey-Smith, S., Hone, E., Pedrini, S., Lim, F., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K., Fuller, S., Brown, B., Gardener, S., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S., Barron, A., Goozee, K., Wahjoepramono, EJ., Asih, P., Doecke, J., Salvado, O., Bush, A., Rowe, C., Gandy, S., Masters, C., (2018), Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease, 62(3), 965-992, Netherlands, IOS Press, DOI: 10.3233/JAD-171145.
  • Brown, B., Sohrabi, H., Taddei, K., Gardener, S., Rainey-Smith, S., Peiffer, J., Xiong, C., Fagan, A., Benzinger, T., Buckles, V., Erickson, K., Clarnette, R., Shah, T., Masters, C., Weiner, M., Cairns, N., Rossor, M., Graff-Radford, N., Salloway, S., Voglein, J., Laske, C., Noble, J., Schofield, P., Bateman, R., Morris, J., Martins, R., (2017), Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer’s disease. Alzheimer's and Dementia, 13(11), 1197-1206, United States, Elsevier Science Inc., DOI: 10.1016/j.jalz.2017.03.008.
  • Brown, B., Rainey-Smith, S., Castalanelli, N., Gordon, N., Markovic, S., Sohrabi, H., Weinborn, M., Laws, S., Doecke, J., Shen, K., Martins, R., Peiffer, JJ., (2017), Study protocol of the Intense Physical Activity and Cognition study: The effect of high-intensity exercise training on cognitive function in older adults. Alzheimer's and Dementia, 3(4), 562-570, United States, Elsevier Science Inc., DOI: 10.1016/j.trci.2017.09.003.
  • Marston, K., Newton, M., Brown, B., Rainey-Smith, S., Bird, S., Martins, R., Peiffer, J., (2017), Intense resistance exercise increases peripheral brain-derived neurotrophic factor. Journal of Science and Medicine in Sport, 20(10), 899-903, Chatswood, NSW, Elsevier Australia, DOI: 10.1016/j.jsams.2017.03.015.
  • Bird, S., Sohrabi, H., Sutton, T., Weinborn, M., Rainey-Smith, S., Brown, B., Patterson, L., Taddei, K., Gupta, V., Carruthers, M., Lenzo, N., Knuckey, N., Bucks, R., Verdile, G., Martins, R., (2016), Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies. Neuroscience & Biobehavioural Reviews, 64(2016), 215-228, Elsevier Ltd, DOI: 10.1016/j.neubiorev.2016.01.004.
  • Burnham, S., Bourgeat, P., Dore, V., Savage, G., Brown, B., Laws, S., Maruff, P., Salvado, O., Ames, D., Martins, R., Masters, C., Rowe, C., Villemagne, V., (2016), Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study. Lancet Neurology, 15(10), 1044-1053, London, UK, Lancet Publishing Group, DOI: 10.1016/S1474-4422(16)30125-9.
  • Chatterjee, P., Lim, F., Shui, G., Gupta, V., James, I., Fagan, A., Xiong, C., Sohrabi, H., Taddei, K., Brown, B., Benzinger, T., Masters, C., Snowden, S., Wenk, M., Bateman, R., Morris, J., Martins, R., (2016), Plasma Phospholipid and Sphingolipid Alterations in Presnilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's disease, 50(3), 887-894, Netherlands, IOS Press, DOI: 10.3233/JAD-150948.
  • Brown, B., Rainey-Smith, S., Villemagne, V., Weinborn, M., Bucks, R., Sohrabi, H., Laws, S., Taddei, K., Macaulay, SL., Ames, D., Fowler, C., Maruff, P., Masters, C., Rowe, C., Martins, R., (2016), The relationship between sleep quality and brain amyloid burden. Sleep, 39(5), 1063-1068, Westchester, USA, Associated Professional Sleep Societies,LLC, DOI: 10.5665/sleep.5756.
  • Rainey-Smith, S., Brown, B., Sohrabi, H., Shah, T., Goozee, K., Gupta, V., Martins, R., (2016), Curcumin and cognition: a randomized, placebo-controlled, double-blind study of community-dwelling older adults. British Journal of Nutrition, 115(2), 2106-2113, Cambridge University Press, DOI: 10.1017/S0007114516001203.
  • Goozee, K., Shah, T., Sohrabi, H., Rainey-Smith, S., Brown, B., Verdile, G., Martins, R., (2016), Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease. British Journal of Nutrition, 115(3), 449-465, Cambridge, United Kingdom, Cambridge University Press, DOI: 10.1017/S0007114515004687.
  • Chatterjee, P., Gupta, V., Fagan, A., Jasielec, M., Xiong, C., Sohrabi, H., Dhaliwal, S., Taddei, K., Bourgeat, P., Brown, B., Benzinger, T., Bateman, R., Morris, J., Martins, R., (2015), Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer's Disease: Baseline Data from a DIAN Cohort Subset. Current Alzheimer Research, 12(2), 157-164, Bussum, Netherlands, Bentham Science Publishers, DOI: 10.2174/1567205012666150204125732.
  • Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, Frontiers Research Foundation, DOI: 10.3389/fnagi.2015.00016.
  • Bourgeat, P., Villemagne, V., Dore, V., Brown, B., Macaulay, SL., Martins, R., Masters, C., Ames, D., Ellis, K., Rowe, C., Salvado, O., Fripp, J., (2015), Comparison of MR-less PiB SUVR quantification methods. Neurobiology of Aging, 36(S1), S159-S166, United States, Elsevier, DOI: 10.1016/j.neurobiolaging.2014.04.033.
  • Brown, B., Bourgeat, P., Peiffer, J., Burnham, S., Laws, S., Rainey-Smith, S., Bartres-Faz, D., Villemagne, V., Taddei, K., Rembach, A., Bush, A., Ellis, K., Macaulay, SL., Rowe, C., Ames, D., Masters, C., Maruff, P., Martins, R., (2014), Influence of BDNF Val66Met on the relationship between physical activity and brain volume. Neurology, 83(15), 1345-52, Lippincott Williams and Wilkins, DOI: 10.1212/WNL.0000000000000867.
  • Villemagne, V., Dore, V., Yates, P., Brown, B., Mulligan, R., Bourgeat, P., Veljanoski, R., Rainey-Smith, S., Ong, K., Rembach, A., Williams, R., Burnham, S., Laws, S., Salvado, O., Taddei, K., Macaulay, SL., Martins, R., Ames, D., Masters, C., Rowe, C., (2014), En Attendant Centiloid. Advances in Research, 2(12), 723-729, Online, Science Domain International, DOI: 10.9734/AIR/2014/11599.
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