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Dr Hamid Sohrabi

Research Fellow

Contact Information Telephone: +61 8 6298 6315, Email: h.sohrabi@ecu.edu.au, Campus: ,
Staff Member Details
Telephone: +61 8 6298 6315
Email: h.sohrabi@ecu.edu.au
Campus:  

 

Hamid is a clinical neuroscientist investigating Alzheimer’s disease diagnosis and treatment. He leads the WA Memory Study, a longitudinal study into the neuropsychological and biological markers dementia due to Alzheimer’s disease.  

Background

Dr Sohrabi completed his PhD in Psychiatry and Clinical Neurosciences at the University of Western Australia (UWA) in 2010. He has authored/co-authored more than 30 papers (23 in the last 5 year) in peer-reviewed journals including Lancet Neurology, Molecular Psychiatry, Neuroscience & Biobehavioral Reviews, Alzheimer’s and Dementia, Neurobiology of Aging, Journal of Alzheimer’s Disease, Translational Psychiatry and so on. Dr Sohrabi is a regular reviewer for different scientific journals as well as being on editorial boards of two journals. He has presented his data in national and international conferences and was awarded a young researcher’s travel fellowship by the American Alzheimer's Association to present at their International Conference (AAIC-2011) in Paris, France. He has also received the Professional Development Award (ASPIRE Professional Award) from Perth Convention Bureau, (Western Australia), May 2013. More recently, he was awarded an Early Career Excellence Award from the Edith Cowan University; ECU, in September 2014. Dr Sohrabi is the winner of the Cecilia Margaret Hudson Dementia Research Award from the Alzheimer’s Australia (2015). Dr Sohrabi’s work on depressive Endophenotype and future risk of AD as well as his work on olfactory and visual senses and their applications in diagnosing and predicting future pathological cognitive decline has received media attention, both nationally and internationally. Dr Sohrabi has recently joined the Department of Biomedical Sciences of Macquarie University on a part time basis, as the Associate Professor in Clinical Neurosciences.

Professional Associations

  • The Australasian Neuroscience Society (2008-Current);
  • Co-Chair of the Early/Mid-Career Researchers Network at Edith Cowan University (2015-2017);
  • The GeneQol Consortium: Genetic Research into Quality of Life (2014-current)
    www.geneqol-consortium.org;
  • The Asian Society Against Dementia (ASAD) (2013- current)
    www.asiandementia.org.

Awards and Recognition

National and International Awards

  • 2014- The Early Career Research Excellence Award; Edith Cowan University;
  • 2013- The Aspire Professional Development Award (ASPIRE Award) from Perth Convention Bureau and Edith Cowan University;
  • 2012- Australian National University Bursary to participate in “One-Week Longitudinal Data Analysis Course”;
  • 2011-Travel Fellowship from the Alzheimer’s Association (US) to attend and present at the Alzheimer’s Association International Conference (AAIC; previously, ICAD), Paris, France.

National and International Research Positions

  • Associate Professor in Clinical Neurosciences, Macquarie University, Sydney, NSW, 201-current;
  • WA Memory Study Lead (2010-current);
  • WA Coordinator of the Dominantly Inherited Alzheimer Network (DIAN) Study (2011-current);
  • WA Site Lead Neuropsychologist for TOMM40 (TOMMORROW) Study (2013-current).

Other

  • 2016- Co-chair and scientific judge for the Western Australia, ASMR;
  • 2016- Judging Panel Member for Fresh Science Competition, Western Australia.

Research Areas and Interests

  • I am interested in psychological, cognitive, and biological markers of cognitive decline in aging and dementia due to Alzheimer’s disease.

Qualifications

  • Doctor of Philosophy, The University of Western Australia.
  • Master degree in Clinical Psychology, Iran, 1995.
  • Bachelor of Clinical Psychology, Iran, 1992.

Research

Recent Research Grants

  • Head Injury and Testosterone (HIT),  Harry Perkins Institute of Medical Research,  Neurotrauma Research Program,  2013 - 2017,  $148,701.
  • Establishing a combined ocular and blood biomarker panel for Alzheimer?s disease.,  Australian National University,  ANU - Dementia CRC - Grant,  2014 - 2015,  $517,977.
  • Personality dimensions and increased risk of late onset Alzheimer's disease,  Edith Cowan University,  ECU Early Career Researcher Grant - 2014,  2014 - 2015,  $15,000.

Recent Publications (within the last five years)

Journal Articles

  • Gardener, S., Rainey-Smith, S., Sohrabi, H., Weinborn, M., Verdile, G., Fernando, B., Lim, Y., Harrington, K., Burnham, S., Taddei, K., Masters, C., Macaulay, S., Rowe, C., Ames, D., Maruff, P., Martins, R., (2017), Increased carbohydrate intake is associated with poorer performance in verbal memory and attention in an APOE genotype-dependent manner. Journal of Alzheimer's Disease, 58(1), 193-201, Netherlands, IOS Press, DOI: 10.3233/JAD-161158.
  • Asih, P., Tegg, M., Sohrabi, H., Carruthers, M., Gandy, S., Saad, F., Verdile, G., Ittner, L., Martins, R., (2017), Multiple mechanisms linking Type 2 Diabetes and Alzheimer's disease: Testosterone as a modifier. Journal of Alzheimer's Disease, 59(2), 445-466, Netherlands, IOS Press, DOI: 10.3233/JAD-161259.
  • Jayakody, D., Friedland, PL., Eikelboom, RH., Martins, R., Sohrabi, H., (2017), A novel study on association between untreated hearing loss and cognitive functions of older adults: Baseline non-verbal cognitive assessment results. Clinical Otolaryngology, In Press(In Press), 10p., Blackwell Publishing Ltd, DOI: 10.1111/coa.12937.
  • Mirmosayyeb, O., Tanhaei, A., Sohrabi, H., Martins, R., Tanhaei, M., Najafi, M., Safaei, A., Meamar, R., (2017), Possible role of common spices as a preventive and therapeutic agent for Alzheimer's disease. International Journal of Preventive Medicine, 8(1), 5-17, DOI: 10.4103/2008-7802.199640.
  • Brown, B., Sohrabi, H., Taddei, K., Gardener, S., Rainey-Smith, S., Peiffer, J., Xiong, C., Fagan, A., Benzinger, T., Buckles, V., Erickson, K., Clarnette, R., Shah, T., Masters, C., Weiner, M., Cairns, N., Rossor, M., Graff-Radford, N., Salloway, S., Voglein, J., Laske, C., Noble, J., Schofield, P., Bateman, R., Morris, J., Martins, R., (2017), Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer?s disease. Alzheimer's and Dementia, In Press(In Press), 10p., United States, Elsevier Science Inc., DOI: 10.1016/j.jalz.2017.03.008.
  • Brini, S., Sohrabi, H., Peiffer, J., Karrasch, M., Hamalainen, H., Martins, R., Fairchild, T., (2017), Physical activity in preventing Alzheimer's disease and cognitive decline: A narrative review. Sports Medicine, In Press(In Press), 16p., New Zealand, Adis int Ltd, DOI: 10.1007/s40279-017-0787-y.
  • Shah, T., Weinborn, M., Verdile, G., Sohrabi, H., Martins, R., (2017), Enhancing Cognitive Functioning in Healthly Older Adults: a Systematic Review of the Clinical Significance of Commercially Available Computerized Cognitive Training in Preventing Cognitive Decline. Neuropsychology Review, 27(1), 62-80, Springer, DOI: 10.1007/s11065-016-9338-9.
  • Goozee, K., Chatterjee, P., James, I., Shen, K., Sohrabi, H., Asih, P., Dave, P., Ball, B., Manyan, C., Taddei, K., Chung, R., Garg, M., Martins, R., (2017), Alterations in erythrocyte fatty acid composition in preclinical Alzheimer?s disease. Scientific Reports, 7(1), Article number 751, Nature Publishing Group, DOI: 10.1038/s41598-017-00751-2.
  • Jayakody, D., Friedland, P., Nel, E., Martins, R., Atlas, M., Sohrabi, H., (2017), Impact of cochlear implantation on cognitive function of older adults: Pilot test results. Otology and Neurotology: an international forum, 38(8), e289-e295, United States, Lippincott Williams & Wilkins, DOI: 10.1097/MAO.0000000000001502.
  • Muller, S., Preische, O., Sohrabi, H., Graber, S., Jucker, M., Dietzsch, J., Ringman, J., Martins, R., McDade, E., Schofield, P., Ghetti, B., Rossor, M., Graff-Radford, N., Levin, J., Galasko, D., Quaid, K., Salloway, S., Xiong, C., Benzinger, T., Buckles, V., Masters, C., Sperling, R., Bateman, R., Morris, J., Laske, C., (2017), Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer?s disease. Scientific Reports, 7(1), Article number 1225, Nature Publishing Group, DOI: 10.1038/s41598-017-01327-w.
  • Chatterjee, P., Lim, F., Shui, G., Gupta, V., James, I., Fagan, A., Xiong, C., Sohrabi, H., Taddei, K., Brown, B., Benzinger, T., Masters, C., Snowden, S., Wenk, M., Bateman, R., Morris, J., Martins, R., (2016), Plasma Phospholipid and Sphingolipid Alterations in Presnilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's disease, 50(3), 887-894, Netherlands, IOS Press, DOI: 10.3233/JAD-150948.
  • Wahjoepramono, EJ., Asih, P., Aniwiyanti, V., Taddei, K., Dhaliwal, S., Fuller, S., Foster, J., Carruthers, M., Verdile, G., Sohrabi, H., Martins, R., (2016), The effects of testosterone supplementation on cognitive functioning in older men. CNS and Neurological Disorders, 15(3), 337-343, Bentham Science Publishers B.V., DOI: 10.2174/1871527315666151110125704.
  • Frost, S., Guymer, R., Aung, K., Macaulay, S., Sohrabi, H., Bourgeat, P., Salvado, O., Rowe, C., Ames, D., Masters, C., Martins, R., Kanagasingam, Y., (2016), Alzheimer's disease and the early signs of age-related macular degeneration. Current Alzheimer Research, 13(11), 1259-1266, Bussum, Netherlands, Bentham Science Publishers Ltd., DOI: 10.2174/1567205013666160603003800.
  • Bates, K., Sohrabi, H., Rainey-Smith, S., Weinborn, M., Bucks, R., Rodrigues, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, L., Gandy, S., (2016), Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women. International Journal of Neuroscience, Article in press(Article in press), 10p., Taylor and Francis Ltd, DOI: 10.1080/00207454.2016.1182527.
  • Brown, B., Rainey-Smith, S., Villemagne, V., Weinborn, M., Bucks, R., Sohrabi, H., Laws, S., Taddei, K., Macaulay, SL., Ames, D., Fowler, C., Maruff, P., Masters, C., Rowe, C., Martins, R., (2016), The relationship between sleep quality and brain amyloid burden. Sleep, 39(5), 1063-1068, Westchester, USA, Associated Professional Sleep Societies,LLC, DOI: 10.5665/sleep.5756.
  • Rainey-Smith, S., Brown, B., Sohrabi, H., Shah, T., Goozee, K., Gupta, V., Martins, R., (2016), Curcumin and cognition: a randomized, placebo-controlled, double-blind study of community-dwelling older adults. British Journal of Nutrition, 115(2), 2106-2113, Cambridge University Press, DOI: 10.1017/S0007114516001203.
  • Gardener, S., Sohrabi, H., Shen, K., Rainey-Smith, S., Weinborn, M., Bates, K., Shah, T., Foster, J., Lenzo, N., Salvado, O., Laske, C., Laws, S., Taddei, K., Martins, R., (2016), Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults. Journal of Alzheimer's Disease, 52(2), 661-672, Netherlands, IOS Press, DOI: 10.3233/JAD-151084.
  • Bird, S., Sohrabi, H., Sutton, T., Weinborn, M., Rainey-Smith, S., Brown, B., Patterson, L., Taddei, K., Gupta, V., Carruthers, M., Lenzo, N., Knuckey, N., Bucks, R., Verdile, G., Martins, R., (2016), Cerebral amyloid-? accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies. Neuroscience & Biobehavioural Reviews, 64(2016), 215-228, Elsevier Ltd, DOI: 10.1016/j.neubiorev.2016.01.004.
  • Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, Frontiers Research Foundation, DOI: 10.3389/fnagi.2015.00016.
  • Laske, C., Sohrabi, H., Jasielec, MS., Muller, S., Koehler, N., Graber, S., Forster, S., Drzezga, A., Mueller-Sarnowski, F., Danek, A., Jucker, M., Bateman, R., Buckles, V., Saykin, A., Martins, R., Morris, J., (2015), Diagnostic Value of Subjective Memory Complaints Assessed with a Single Item in Dominantly Inherited Alzheimer?s Disease: Results of the DIAN Study. BioMed Research International, 2015(2015), Article no. 828120, New York, USA, Hindawi Publishing Corporation, DOI: 10.1155/2015/828120.
  • Johnson, L., Sohrabi, H., Hall, J., Taddei, K., Edwards, M., O'Bryant, S., Martins, R., (2015), A depressive endophenotype of poorer cognition among cognitively healthy community-dwelling adults: results from the Western Australia memory study. International Journal of Geriatric Psychiatry, 30(8), 881-886, Wiley, DOI: 10.1002/gps.4231.
  • Sutton, T., Sohrabi, H., Rainey-Smith, S., Bird, S., Weinborn, M., Martins, R., (2015), The role of APOE-?4 and beta amyloid in the differential rate of recovery from ECT: a review. Translational Psychiatry, 5(e539), 1-8, London, UK, Nature Publishing Group, DOI: 10.1038/tp.2015.39.
  • Asih, P., Wahjoepramono, EJ., Aniwiyanti, V., Wijaya, L., De Ruyck, K., Taddei, K., Fuller, SJ., Sohrabi, H., Dhaliwal, SS., Verdile, G., Carruthers, M., Martins, R., (2015), Testosterone Replacement Therapy in Older Male Subjective Memory Complainers: Double-Blind Randomized Crossover Placebo-Controlled Clinical Trial of Physiological Assessment and Safety. CNS and Neurological Disorders, 14(5), 576-586, Bussum, Netherlands, Bentham Science Publishers B.V..
  • Goozee, K., Shah, T., Sohrabi, H., Rainey-Smith, S., Brown, B., Verdile, G., Martins, R., (2015), Examining the potential clinical value of curcumin in the prevention and diagnosis of Alzheimer's disease. British Journal of Nutrition, 115(3), 449-465, Cambridge, United Kingdom, Cambridge University Press, DOI: 10.1017/S0007114515004687.
  • Chatterjee, P., Gupta, V., Fagan, A., Jasielec, M., Xiong, C., Sohrabi, H., Dhaliwal, S., Taddei, K., Bourgeat, P., Brown, B., Benzinger, T., Bateman, R., Morris, J., Martins, R., (2015), Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer's Disease: Baseline Data from a DIAN Cohort Subset. Current Alzheimer Research, 12(2), 157-164, Bussum, Netherlands, Bentham Science Publishers.
  • Gardener, S., Rainey-Smith, S., Barnes, M., Sohrabi, H., Weinborn, M., Lim, Y., Harrington, K., Taddei, K., Gu, Y., Rembach, A., Szoeke, C., Ellis, K., Masters, C., Macaulay, S., Rowe, C., Ames, D., Keogh, J., Scarmeas, N., Martins, R., For the Aibl, RG., (2014), Dietary patterns and cognitive decline in an Australian study of ageing. Molecular Psychiatry, 20(7), 860-866, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2014.79.
  • Shah, T., Verdile, G., Sohrabi, H., Campbell, A., Putland, E., Cheetham, C., Dhaliwal, S., Weinborn, M., Maruff, P., Darby, D., Martins, R., (2014), A combination of physical activity and computerized brain training improves verbal memory and increases cerebral glucose metabolism in the elderly. Translational Psychiatry, 4(12), Article no. e487, United Kingdom, Nature Publishing Group, DOI: 10.1038/tp.2014.122.
  • Laske, C., Sohrabi, H., Frost, S., Lopez-De-Ipina, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S., Mueller, S., Linnemann, C., Bridenbaugh, S., Kanagasingam, Y., Martins, R., O?bryant, S., (2014), Innovative diagnostic tools for early detection of Alzheimer?s disease. Alzheimer's and Dementia, 11(5), 561-578, United States, Elsevier Science Inc., DOI: 10.1016/j.jalz.2014.06.004.
  • Frost, S., Kanagasingam, Y., Sohrabi, H., Vignarajan, J., Bourgeat, P., Salvado, O., Villemagne, V., Rowe, C., Macaulay, L., Szoeke, C., Ellis, K., Ames, D., Masters, C., Rainey-Smith, S., Martins, R., (2013), Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease. Translational Psychiatry, 3(February), 1-8, United Kingdom, Nature Publishing Group.
  • Frost, S., Kanagasingam, Y., Sohrabi, H., Taddei, K., Bateman, R., Morris, J., Benzinger, T., Goate, A., Masters, C., Martins, R., (2013), Pupil Response Biomarkers Distinguish Amyloid Precursor Protein Mutation Carriers from Non-Carriers. Current Alzheimer Research, 10(8), 790-796, Netherlands, Bentham Science Publishers.
  • Frost, S., Kanagasingam, Y., Sohrabi, H., Bourgeat, P., Villemagne, V., Rowe, C., Macaulay, SL., Szoeke, C., Ellis, K., Ames, D., Masters, C., Rainey-Smith, S., Martins, R., (2013), Pupil Response Biomarkers for Early Detection and Monitoring of Alzheimer's Disease. Current Alzheimer Research, 10(9), 931-939, Bentham Science Publishers.
  • Lau, S., Bates, K., Sohrabi, H., Rodrigues, M., Martins, G., Dhaliwal, S., Taddei, K., Laws, S., Martins, I., Mastaglia, F., Foster, J., Phillips, J., Martins, R., (2012), Functional effects of genetic polymorphism in inflammatory genes in subjective memory complainers. Neurobiology of Aging, 33(6), 1054-1056, United States, Elsevier, DOI: 10.1016/j.neurobiolaging.2010.09.003.
  • Brown, B., Peiffer, J., Sohrabi, H., Mondal, A., Gupta, V., Rainey-Smith, S., Taddei, K., Burnham, S., Ellis, K., Szoeke, C., Masters, CL., Ames, D., Rowe, C., Martins, R., (2012), Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2(2012), art. no. e191 , DOI: 10.1038/tp.2012.118.
  • Hata, S., Taniguchi, M., Piao, Y., Ikeuchi, T., Fagan, A., Holtzman, D., Bateman, R., Sohrabi, H., Martins, R., Gandy, S., Urakami, K., Suzuki, T., (2012), Multiple ?-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer?s disease subjects. Molecular Neurodegeneration, 7(1), art. no. 16 , United Kingdom, BioMed Central, DOI: 10.1186/1750-1326-7-16.
  • Sohrabi, H., Bates, K., Weinborn, M., Johnston, A., Bahramian, A., Taddei, K., Laws, S., Rodrigues, M., Morici, M., Howard, M., Martins, G., Mackay-Sim, A., Gandy, S., Martins, R., (2012), Olfactory discrimination predicts cognitive decline amongst community-dwelling older adults. Translational Psychiatry , 2(2012), art. no. e118 , Nature Publishing Group, DOI: 10.1038/tp.2012.43.
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