As our understanding of systems biology grows, it is clear that an organism's genes should not be separated from the context of its resident microbiome and exposome. An understanding of co-metabolome variation is essential to understand fully these systematic interactions. The Centre for Integrative Metabolomics & Computational Biology (CIM-CB) aims to investigate these fundamental biological processes through the use of state-of-the-art mass spectrometry to conduct comprehensive metabolic profiling of specific biofluids such as blood, urine, feces, cell culture, biofilms, and plant extracts providing a top-down “systems level” measure of the biochemical, physiological, nutrient uptake, and environmental exposures of a given system. By taking advantage of high resolution 'omic technologies combined with comprehensive state-of-the-art computational biology approaches, the end products and consequences of external perturbations and internal responses can be captured.
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