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  2. Human Molecular Genetics [SCH2226]

School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

Please note that given the circumstances of COVID-19, there may be some modifications to the assessment schedule promoted in Handbook for Semester 1 2020 Units. Students will be notified of all approved modifications by Unit Coordinators via email and Unit Blackboard sites. Where changes have been made, these are designed to ensure that you still meet the unit learning outcomes in the context of our adjusted teaching and learning arrangements.

  • Unit Title

    Human Molecular Genetics

  • Unit Code

    SCH2226

  • Year

    2020

  • Enrolment Period

    1

  • Version

    2

  • Credit Points

    15

  • Full Year Unit

    N

  • Mode of Delivery

    On Campus

  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit commences with an analysis of DNA structure, replication and function in prokaryotes and eukaryotes. The mapping and sequencing of the human genome is discussed, followed by consideration of penetrance, expressivity, essential genes, lethal alleles, gene silencing, and genomic imprinting. Focus then switches to gene expression in prokaryotes and eukaryotes before the genetics of cancer integrates central human molecular genetic concepts.

Prerequisite Rule

Students must have passed SCH1133

Equivalent Rule

Unit was previously coded SCH3336

Learning Outcomes

On completion of this unit students should be able to:

  1. Explain how prokaryote and eukaryote molecular mechanisms of DNA replicate into a stepwise temporal sequence of events.
  2. Communicate an advanced understanding of the medical research topic to illustrate broad subject knowledge.
  3. Implement Molecular Biology techniques in collaboration with a group project so as to understand positional cloning and sequencing.

Unit Content

  1. The genetic material and DNA Replication.
  2. Extensions of Mendelian genetic principles.
  3. Mapping and sequencing the human genome: The Human Genome Diversity Panel: Worldwide Human Relationships.
  4. Transcription, translation and the regulation of gene expression in bacteria.
  5. Regulation of gene expression in eukaryotes.
  6. Mapping bacterial genomes.
  7. Expression vector cloning of human gene exons.
  8. Genetics of cancer.

Learning Experience

Students will attend on campus classes as well as engage in learning activities through ECU Blackboard.

JoondalupMount LawleySouth West (Bunbury)
Semester 113 x 2 hour labNot OfferedNot Offered
Semester 113 x 2 hour lectureNot OfferedNot Offered

For more information see the Semester Timetable

Additional Learning Experience Information

Lectures incorporate key questions designed to prime students for major concepts, and summaries of major ideas and critical points. Sporadically guest speakers will be invited that highlight student opportunities for future employment. The use of digital technology engages students in their development of academic writing and provides real world readiness. In the laboratory, students work in pairs to conduct experiments and critically analyse their findings. Each week, one group of students presents a review of laboratory progress to the rest of the class, developing self-management and responsibility capabilities.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescriptionValue
TestMid semester test30%
Laboratory WorkLaboratory report20%
Laboratory Work ^Practical test10%
ExaminationSemester examination40%

^ Mandatory to Pass

Core Reading(s)

  • Russell, P. (2014). iGenetics: Pearson New International Edition: A Molecular Approach (3rd ed.). Pearson Education Limited. Retrieved from http://ezproxy.ecu.edu.au/login?url=https://ebookcentral.proquest.com/lib/ecu/detail.action?docID=5176442

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH2226|2|1

School: Medical and Health Sciences

This unit information may be updated and amended immediately prior to semester. To ensure you have the correct outline, please check it again at the beginning of semester.

Please note that given the circumstances of COVID-19, there may be some modifications to the assessment schedule promoted in Handbook for this unit. All assessment changes will be published by 27 July 2020. All students are reminded to check handbook at the beginning of semester to ensure they have the correct outline.

  • Unit Title

    Human Molecular Genetics

  • Unit Code

    SCH2226

  • Year

    2020

  • Enrolment Period

    2

  • Version

    2

  • Credit Points

    15

  • Full Year Unit

    N

  • Mode of Delivery

    On Campus

  • Unit Coordinator

    Dr Lois Ann BALMER

Description

This unit commences with an analysis of DNA structure, replication and function in prokaryotes and eukaryotes. The mapping and sequencing of the human genome is discussed, followed by consideration of penetrance, expressivity, essential genes, lethal alleles, gene silencing, and genomic imprinting. Focus then switches to gene expression in prokaryotes and eukaryotes before the genetics of cancer integrates central human molecular genetic concepts.

Prerequisite Rule

Students must have passed SCH1133

Equivalent Rule

Unit was previously coded SCH3336

Learning Outcomes

On completion of this unit students should be able to:

  1. Explain how prokaryote and eukaryote molecular mechanisms of DNA replicate into a stepwise temporal sequence of events.
  2. Communicate an advanced understanding of the medical research topic to illustrate broad subject knowledge.
  3. Implement Molecular Biology techniques in collaboration with a group project so as to understand positional cloning and sequencing.

Unit Content

  1. The genetic material and DNA Replication.
  2. Extensions of Mendelian genetic principles.
  3. Mapping and sequencing the human genome: The Human Genome Diversity Panel: Worldwide Human Relationships.
  4. Transcription, translation and the regulation of gene expression in bacteria.
  5. Regulation of gene expression in eukaryotes.
  6. Mapping bacterial genomes.
  7. Expression vector cloning of human gene exons.
  8. Genetics of cancer.

Learning Experience

Students will attend on campus classes as well as engage in learning activities through ECU Blackboard.

JoondalupMount LawleySouth West (Bunbury)
Semester 113 x 2 hour labNot OfferedNot Offered
Semester 113 x 2 hour lectureNot OfferedNot Offered

For more information see the Semester Timetable

Additional Learning Experience Information

Lectures incorporate key questions designed to prime students for major concepts, and summaries of major ideas and critical points. Sporadically guest speakers will be invited that highlight student opportunities for future employment. The use of digital technology engages students in their development of academic writing and provides real world readiness. In the laboratory, students work in pairs to conduct experiments and critically analyse their findings. Each week, one group of students presents a review of laboratory progress to the rest of the class, developing self-management and responsibility capabilities.

Assessment

GS1 GRADING SCHEMA 1 Used for standard coursework units

Students please note: The marks and grades received by students on assessments may be subject to further moderation. All marks and grades are to be considered provisional until endorsed by the relevant Board of Examiners.

ON CAMPUS
TypeDescriptionValue
TestMid semester test30%
Laboratory WorkLaboratory report20%
Laboratory Work ^Practical test10%
ExaminationSemester examination40%

^ Mandatory to Pass

Core Reading(s)

  • Russell, P. (2014). iGenetics: Pearson New International Edition: A Molecular Approach (3rd ed.). Pearson Education Limited. Retrieved from http://ezproxy.ecu.edu.au/login?url=https://ebookcentral.proquest.com/lib/ecu/detail.action?docID=5176442

Disability Standards for Education (Commonwealth 2005)

For the purposes of considering a request for Reasonable Adjustments under the Disability Standards for Education (Commonwealth 2005), inherent requirements for this subject are articulated in the Unit Description, Learning Outcomes and Assessment Requirements of this entry. The University is dedicated to provide support to those with special requirements. Further details on the support for students with disabilities or medical conditions can be found at the Access and Inclusion website.

Academic Misconduct

Edith Cowan University has firm rules governing academic misconduct and there are substantial penalties that can be applied to students who are found in breach of these rules. Academic misconduct includes, but is not limited to:

  • plagiarism;
  • unauthorised collaboration;
  • cheating in examinations;
  • theft of other students' work;

Additionally, any material submitted for assessment purposes must be work that has not been submitted previously, by any person, for any other unit at ECU or elsewhere.

The ECU rules and policies governing all academic activities, including misconduct, can be accessed through the ECU website.

SCH2226|2|2