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    • Zhiwei Zhong
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      Zhiwei Zhong

Efficacy of exosome derived from 3D printing stem cell combines with hydrogel to promote neural repair after traumatic brain injury

Student name:

Zhiwei Zhong (PhD candidate)

Supervisors:

1. Professor Elin Gray
2. Professor Simon Laws
3. Dr Yimin Xu (Shantou University, China)

Summary of thesis:

Traumatic brain injury (TBI) is a neurological disease with high mortality and disability, but lack of effective therapy for nerve injury. Exosomes derived from stem cells can serve as paracrine factors and mediate the biological effects of stem cells, which can improve the local microenvironment and contribute to the repair of nerve injury. In addition, exosome carriers are beneficial to the local release and concentration maintenance of exosomes. We propose to enhance exosome production and their effect on nerve repair in TBI rats. We also aim to deliver an effective exosome transplantation process for nerve repair in TBI rats.

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