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    Anika Lamisa

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Unveiling a genomic signature of metabolic and inflammatory biomarkers in Alzheimer’s disease

Student name:

Anika Lamisa

Supervisors:

  1. Professor Simon Laws
  2. Dr Emmanuel Adewuyi
  3. Dr Tenielle Porter

Summary of thesis:

Despite long-standing efforts, Alzheimer’s disease (AD) has no known curative treatments, and its diagnosis is challenging due to a lack of blood-based biomarkers. Over the years, evidence points to the critical roles of metabolic and neuro-inflammatory processes in the risk of AD. By understanding the complex relationship between AD and metabolic and inflammatory biomarkers, it may be possible to identify credible biomarkers or potential therapeutic targets. My PhD project seeks to investigate this relationship using powerful statistical genetic approaches, and by integrating a range of in-house and large-scale genetic data.

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