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    Zhixian Chen

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The Role of Serum IgG N-glycosylation in Diagnosis, Disease Activity, Prognosis and Patient Stratification of Sjögren’s Syndrome

Student name:

Zhixian Chen (PhD candidate)

Supervisors:

  1. Professor Wei Wang
  2. Dr Manshu Song
  3. Professor Chris Abbiss
  4. Professor Lin Ling

Summary of thesis:

Immunoglobulin G (IgG) N-glycosylation has demonstrated association with various autoimmune diseases. This project aims to explore the potential of IgG N-glycosylation profiles as biomarkers for diagnosis, disease activity and prognosis of SS. Furthermore, this project will use machine learning approaches to stratify SS patients based on their IgG N-glycosylation profiles.

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