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  • Yannick Gillet

    Yannick Gillet

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Yannick Gillet

Overview of thesis

Extremophiles have long captivated scientists with their ability to flourish in hostile environments—extreme pH, salinity, temperature, or pressure. Their robustness makes them valuable for next-generation industrial biotechnology. Yet, not all extremophiles are ideal platforms for rapid and scalable bioproduction. Enter Vibrio natriegens—a marine bacterium renowned for its unmatched growth rate and metabolic versatility.

With a doubling time of less than 10 minutes and a natural tolerance to seawater salinity, V. natriegens offers an unprecedented chassis for sustainable biomanufacturing. Its capacity for rapid protein expression, broad substrate utilization, and compatibility with synthetic biology tools positions it as a compelling alternative to traditional model organisms. Unlike freshwater-dependent systems, V. natriegens enables bioprocesses based on seawater—minimizing freshwater use, reducing costs, and aligning with environmentally responsible goals.

This project harnesses multi-omics and synthetic biology to engineer V. natriegens for the efficient production of high-value bioproducts. By unlocking its full biotechnological potential, we aim to establish a new paradigm in industrial microbiology—one that is faster, more flexible, and fundamentally more sustainable.

Contact

Yannick Gillet
PhD Student
Conservation and Biodiversity Research Center (CBRC)
School of Science
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