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Dr Leslie Calapre

Research Fellow

Contact Information Telephone: +61 8 6304 2816, Email: l.calapre@ecu.edu.au, Campus: Joondalup, Room: JO17.209
Staff Member Details
Telephone: +61 8 6304 2816
Email: l.calapre@ecu.edu.au
Campus: Joondalup  
Room: JO17.209  

 

Dr Leslie Calapre is a Research Fellow in the School of Medical and Health Sciences.

Research Areas and Interests

  • Liquid Biopsy for Melanoma
  • Circulating Tumour DNA
  • Environmental stressors and skin cancers

Qualifications

  • Doctor of Philosophy, Edith Cowan University, 2015.
  • Bachelor of Science Human Biology (Honours), Edith Cowan University, 2011.
  • Bachelor of Science (Biomedical Science), Edith Cowan University, 2010.

Research

Recent Research Grants

  • Enhancing Methodologies for Circulating Tumour DNA (ctDNA) Analysis,  Edith Cowan University,  ECU Early Career Researcher Grant - 2017,  2017 - 2018,  $30,000.

Recent Publications (within the last five years)

Journal Articles

  • Gray, E., Witkowski, T., Pereira, M., Calapre, L., Herron, K., Irwin, D., Chapman, B., Khattak, M., Raleigh, J., Hatzimihalis, A., Cebon, J., Sandhu, S., McArthur, G., Millward, M., Ziman, M., Dubrovic, A., Wong, S., (2019), Genomic Analysis of Circulating Tumor DNA Using a Melanoma-Specific UltraSEEK Oncogene Panel. The Journal of Molecular Diagnostics, 21(3), 418-426, DOI: 10.1016/j.jmoldx.2018.12.001.
  • Calapre, L., Giardina, T., Robinson, C., Reid, A., Al-Ogaili, Z., Pereira, M., McEvoy, A., Warburton, L., Hayward, N., Khattak, M., Meniawy, T., Millward, M., Amanuel, B., Ziman, M., Gray, E., (2019), Locus-specific concordance of genomic alterations between tissue and plasma circulating tumor DNA in metastatic melanoma. Molecular Oncology, 13(2019), 171-184, United Kingdom, John Wiley & Sons Ltd, DOI: 10.1002/1878-0261.12391.
  • McEvoy, A., Warburton, L., Al-Ogaili, Z., Celliers, L., Calapre, L., Pereira, M., Khattak, M., Meniawy, T., Millward, M., Ziman, M., Gray, E., (2018), Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients. BMC Cancer, 18(1), Article no. 726, United Kingdom, BioMed Central Ltd, DOI: 10.1186/s12885-018-4637-6.
  • Beasley, A., Isaacs, T., Khattak, M., Freeman, J., Allcock, R., Chen, F., Pereira, M., Yau, K., Bentel, J., Vermeulen, T., Calapre, L., Millward, M., Ziman, M., Gray, E., (2018), Clinical Application of Circulating Tumor Cells and Circulating Tumor DNA in Uveal Melanoma. JCO Precision Oncology, 2(May 17, 2018), 12p., United States, American Society of Clinical Oncology, DOI: 10.1200/PO.17.00279.
  • McEvoy, A., Calapre, L., Pereira, M., Giardina, T., Robinson, C., Khattak, M., Meniawy, T., Pritchard, A., Hayward, N., Amanuel, B., Millward, M., Ziman, M., Gray, E., (2017), Sensitive droplet digital PCR method for detection of TERT promoter mutations in cell free DNA from patients with metastatic melanoma. Oncotarget, 8(45), 78890-78900, Albany, United States, Impact Journals LLC, DOI: 10.18632/oncotarget.20354.
  • Calapre, L., Gray, E., Kurdykowski, S., David, A., Descargues, P., Ziman, M., (2017), SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes. BMC Dermatology, 17(June 2017), Article No. 8, London, United Kingdom, BioMed Central, DOI: 10.1186/s12895-017-0060-y.
  • Calapre, L., Warburton, L., Millward, M., Ziman, M., Gray, E., (2017), Circulating tumour DNA (ctDNA) as a liquid biopsy for melanoma. Cancer Letters, 404(28 Sept, 2017), 62-69, Shannon, Ireland, Elsevier, DOI: 10.1016/j.canlet.2017.06.030.
  • Calapre, L., Gray, E., Kurdykowski, S., David, A., Hart, P., Descargues, P., Ziman, M., (2016), Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo. BMC Dermatology, 16(1), Article no. 6, London, UK, BioMed Central Ltd., DOI: 10.1186/s12895-016-0043-4.
  • Gray, E., Reid, A., Bowyer, S., Calapre, L., Siew, K., Pearce, R., Cowell, L., Frank, M., Millward, M., Ziman, M., (2015), Circulating Melanoma Cell Subpopulations: Their Heterogeneity and Differential Responses to Treatment. Journal of Investigative Dermatology, 135(8), 2040-2048, London, United Kingdom, Nature Publishing Group, DOI: 10.1038/jid.2015.127.
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