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Suboptimal Health and Glycomics

The Suboptimal health and glycomics research team aims to integrate subjective (suboptimal health) and objective (N-glycan) markers of health and establish a standardised screening and monitoring tool for cardio-metabolic disorders by constructing a dynamic glycan screening panel. These derived profiles will be used as tools (biomarkers) of a risk continuum for screening chronic diseases and their relation to various lifestyle and environmental factors, as well as monitoring the progression of suboptimal health status towards cardio-metabolic disorders, such as metabolic syndrome, diabetes, cardiovascular and renal diseases.

Research Interests

  • Genetic epidemiology (biomarker screening, validation and trial)
  • Global health (disease burden, and chronic diseases diagnosis & management)
  • Genomics and glycomics (bioinformatics, DNA sequencing and N-Glycan profiling)

For more information, contact Professor Wei Wang

Current Projects

  • Human Glycome Project
    • Inter- and Intra-population diversities of glycan profiling
  • Suboptimal Health
    • Suboptimal health status assessment as a measure for prognosis of preeclampsia, cardiovascular disease, diabetes and biological ageing.
  • Global Health  
    • Subjective (suboptimal health) and objective (N-glycan) markers of health research in three major ethnic populations:  African, Asian, and Caucasian.
  • The Nathan Centre for rare diseases
  • Glycan Aging Study

Postgraduate student project opportunities

  • Towards personalised medicine via population-based study of variability of the human IgG glycome
  • Profiling IgG N-glycans as biomarkers of the ageing process: The Busselton Healthy Ageing Study
  • Suboptimal health: A new instrument for chronic disease assessment

Research team

Group Leader

Professor Wei Wang

PhD students

  • Andrea Lyon
  • Caipan Gong
  • Dong Lin
  • Hongli Sun
  • Jiangyue Yao
  • Jinxia Zhang
  • Dr Lan Chen
  • Pengxiang Ying
  • Sean Oh
  • Wanqi Wang
  • Weijie Cao
  • Zhixian Chen
  • Zhuoqiao He

Publications

View the team's publications here

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