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Associate Professor Simon Laws

Genomic Leader/Deputy CSO (CRC-MH)

Contact Information Telephone: +61 8 6304 5128, Mobile: 0408 789 680, Email: s.laws@ecu.edu.au, Campus: Joondalup, Room: JO17.210
Staff Member Details
Telephone: +61 8 6304 5128
Mobile: 0408 789 680
Email: s.laws@ecu.edu.au
Campus: Joondalup  
Room: JO17.210  

 

Simon is an Associate Professor in the School of Medical and Health Sciences where he leads the Collaborative Genomics Group. Simon is also currently the Deputy Chief Scientific Officer of the Cooperative Research Centre (CRC) for Mental Health.

Background

  • Nov 2011 – present: Associate Professor, Edith Cowan University, Perth, Australia
  • Nov 2011 – present: Deputy Chief Scientific Officer, Cooperative Research Centre (CRC) for Mental Health www.mentalhealthcrc.com.au
  • April 2009 – Nov 2011: Research Fellow, Edith Cowan University, Perth, Australia        
  • Nov 2007 – Mar 2009: Research Fellow, Department of Psychiatrie und Psychotherapie, Neurogenetics Laboratory, Technische Universität München, Germany     
  • Jan 2005 – Oct 2007: Post-Doctoral Research Fellow, Department of Psychiatrie und Psychotherapie, Neurogenetics Laboratory, Technische Universität München, Germany       
  • Mar 2004 – Dec 2004: Post-Doctoral Research Fellow, McCusker Alzheimer’s Research Foundation, Perth, Australia     
  • Jul 2003 – Mar 2004: Research Associate, Alzhyme Pty Ltd, Perth, Australia                                                                                                                                                              

Professional Associations

  • 2014 – present: Australasian Neuroscience Society (ANS)
  • 2013 – present: Alzheimer’s Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) – including membership of the Blood-based Biomarker Professional Interest Area (PIA)
  • 2012 – present: Australian Society for Biochemistry and Molecular Biology (ASBMB)
  • 2011 – present: Australian Society for Medical Research (ASMR)

Research Areas and Interests

Associate Professor Laws currently leads The Collaborative Genomics Group, within the Centre of Excellence for Alzheimer’s Disease Research and Care part of ECU’s School of Medical and Health Sciences. His research primarily focuses on understanding the genetic and epigenetic architecture of Alzheimer’s Disease and related phenotypes, such as changes in memory performance and pathognomonic features. His group utilizes an integrative “omic” approach to Alzheimer’s Disease research through combining genetic, epigenetic and comprehensive longitudinal phenotype data. With the following primary research foci:

Understanding the Genomic Architecture of Rates of Change in AD-related Phenotypes

  • Develop genetic/epigenetic risk profiles for rates of change
  • Determine if peripheral methylation patterns track with AD phenotypes

The interaction of genomics and modifiable lifestyle factors and the impact on rates of change in AD-related phenotypes

  • Understanding the genetic basis of differential effects of lifestyle patterns/choices
  • Determine the impact of positive lifestyle choices on peripheral methylation patterns

Associate Professor Laws also undertakes broader genetic and epigenetic collaborative research with scientists in the Australian research community.

Qualifications

  • Doctor of Philosophy, The University of Western Australia, 2003.
  • Bachelor of Science (Medical Science), Curtin University of Technology, 1999.

Research

Recent Research Grants

  • Biomarkers and Early Intervention for Neurodegeneration,  CRC For Mental Health,  CRC Grant,  2012 - 2018,  $674,185.
  • Medical and Health Research Infrastructure Fund 2016 (Round 20),  Department of Health WA,  Medical and Health Research Infrastructure,  2017 - 2018,  $18,077.
  • Genetic Linkages to mTOR pathway dysregulation and development of Alzheimers Disease,  CRC For Mental Health,  WES Study,  2015 - 2018,  $524,000.
  • 4.1 Biomarkers for Early Diagnosis of AD and PD,  CRC For Mental Health,  CRC Grant,  2011 - 2018,  $7,524,765.
  • Impact of genetics on the effect that modifiable lifestyle factors have on rates of change in Alzheimers Disease,  Equity Trustees Limited,  Mason Foundation National Medical Program (funded by the J. J. Mason & H.S. Williams Memorial Foundation),  2016 - 2017,  $55,370.
  • Development and refinement of methods for early and specific diagnosis of Alzheimer's disease, quantification of rates of change in the pathological processes and determination of the resultant effects on cognition.,  Fil Foundation,  Grant,  2015 - 2017,  $417,506.
  • The effect of high-intensity exercise on Alzheimer?s disease-related gene expression,  Brain Foundation,  Research Gifts Program,  2017,  $39,875.
  • In vitro functional analysis of Alzheimer?s disease associated genetic variants,  Department of Health WA,  Near Miss Merit Awards,  2015 - 2016,  $75,000.
  • CRC for Mental Health - Neurogenerative disease: Genome-Wide Association Studies (GWAS) study ,  CRC For Mental Health,  GWAS Study,  2014 - 2016,  $395,000.
  • Validation of genetic variants and their functional implications in Alzheimers Disease,  ANZ Executors and Trustee Company Limited,  Judith Jane Mason and Harold Stannett Williams Memorial Foundation - National Medical & Scientific Grants,  2014 - 2015,  $40,000.
  • Western Australian Zebrafish Facility,  Australian Research Council,  Grant - Linkage (Infrastructure),  2014,  $682,000.
  • Discovery and Validation of Alzheimer's disease biomarkers in human plasma,  National Health and Medical Research Council,  Project Grants,  2011 - 2014,  $352,524.
  • AIBL: Imaging and genetic study add-ons (ECU project: Genomic Studies - Candidate Gene Validation Stream),  Confidential,  Confidential,  2011 - 2012,  $95,238.
  • Neon Transfection System and Biomedical Research Grade -30oC Freezer for Alzheimer?s and Melanoma Research,  National Health and Medical Research Council,  Equipment Grant 2011,  2011 - 2012,  $10,927.
  • NEW INDEPENDENT RESEARCHER INFRASTRUCTURE SUPPORT (NIRIS) AWARDS 2011,  Medical and Health Research Infrastructure Council WA,  New Independent Researcher Infrastructure Support (NIRIS),  2011 - 2012,  $10,000.
  • Molecular & neuropsychological predictive markers of cognitive decline,  National Health and Medical Research Council,  Grant,  2005 - 2007,  $423,750.

Recent Publications (within the last five years)

Journal Articles

  • Lim, YY., Rainey-Smith, S., Lim, Y., Laws, S., Gupta, V., Porter, T., Bourgeat, P., Ames, D., Fowler, C., Salvado, O., Villemagne, V., Rowe, C., Masters, C., Zhou, XF., Martins, R., Maruff, P., (2017), BDNF Val66Met in preclinical Alzheimer?s disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF. International Psychogeriatrics, In Press(In Press), 10p., United Kingdom, Cambridge University Press, DOI: 10.1017/S1041610217001284.
  • Villemagne, V., Dore, V., Bourgeat, P., Burnham, S., Laws, S., Salvado, O., Masters, C., Rowe, C., (2017), A?-amyloid and Tau Imaging in Dementia. Seminars in Nuclear Medicine, 47(1), 75-88, W.B Saunders, DOI: 10.1053/j.semnuclmed.2016.09.006.
  • Hollands, S., Lim, YY., Laws, S., Villemagne, V., Pietrzak, R., Harrington, K., Porter, T., Snyder, P., Ames, D., Fowler, C., Rainey-Smith, S., Martins, R., Salvado, O., Robertson, J., Rowe, C., Masters, C., Maruff, P., (2017), APOE e4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults. Journal of Alzheimer's Disease, 57(2), 411-422, Netherlands, IOS Press, DOI: 10.3233/JAD-161019.
  • Cardoso, B., Hare, D., Lind, M., McLean, C., Volitakis, I., Laws, S., Masters, C., Bush, A., Roberts, B., (2017), The APOE ?4 Allele is associated with lower selenium levels in the brain: Implications for Alzheimer?s disease. ACS Chemical Neuroscience, 8(7), 1459-1464, United States, American Chemical Society, DOI: 10.1021/acschemneuro.7b00014.
  • Harrington, K., Lim, YY., Ames, D., Hassenstab, J., Laws, S., Martins, R., Rainey-Smith, S., Robertson, J., Rowe, C., Salvado, O., Dore, V., Villemagne, V., Snyder, P., Masters, C., Maruff, P., (2017), Amyloid b?associated cognitive decline in the absence of clinical disease progression and systemic illness. Alzheimer's and Dementia, 8(2017), 156-164, United States, Elsevier Science Inc., DOI: 10.1016/j.dadm.2017.05.006.
  • Lim, YY., Williamson, R., Laws, S., Villemagne, V., Bourgeat, P., Fowler, C., Rainey-Smith, S., Salvado, O., Martins, R., Rowe, C., Masters, C., Maruff, P., (2017), Effect of APOE genotype on amyloid deposition, brain volume, and memory in cognitively normal older individuals. Journal of Alzheimer's Disease, 58(4), 1293-1302, Netherlands, IOS Press, DOI: 10.3233/JAD-170072.
  • Laws, S., Gaskin, S., Woodfield, A., Srikanth, V., Bruce, D., Fraser, P., Porter, T., Newsholme, P., Wijesekara, N., Burnham, S., Dore, V., Li, Q., Maruff, P., Masters, C., Rainey-Smith, S., Rowe, C., Salvado, O., Villemagne, V., Martins, R., Verdile, G., (2017), Insulin resistance is associated with reductions in specific cognitive domains and increases in CSF tau in cognitively normal adults. Scientific Reports, 7(1), Article 9766, United Kingdom, Nature Publishing Group, DOI: 10.1038/s41598-017-09577-4.
  • Holmes, S., Esterlis, I., Mazure, C., Lim, YY., Ames, D., Rainey-Smith, S., Fowler, C., Ellis, K., Martins, R., Salvado, O., Dore, V., Villemagne, V., Rowe, C., Laws, S., Masters, C., Pietrzak, R., Maruff, P., (2017), Trajectories of depressive and anxiety symptoms in older adults: a 6-year prospective cohort study. International Journal of Geriatric Psychiatry, epub ahead of print(epub ahead of print), 9p., John Wiley and Sons Ltd.
  • Pietrzak, R., Laws, S., Lim, YY., Bender, S., Porter, T., Doecke, J., Ames, D., Fowler, C., Masters, C., Milicic, L., Rainey-Smith, S., Villemagne, V., Rowe, C., Martins, R., Maruff, P., (2017), Plasma Cortisol,Brain Amyloid-?, and Cognitive Decline in Preclinical Alzheimer?s Disease:A 6-Year Prospective Cohort Study. Biological Psychiatry, 2(1), 45-52, Elsevier Inc, DOI: 10.1016/j.bpsc.2016.08.006.
  • Pietrzak, R., Laws, S., Lim, YY., Bender, S., Porter, T., Doecke, J., Ames, D., Fowler, C., Masters, C., Milicic, L., Rainey-Smith, S., Villemagne, V., Rowe, C., Martins, R., Maruff, P., (2016), Plasma cortisol, brain amyloid-?, and cognitive decline in preclinical Alzheimer?s disease: A 6-year prospective cohort study. Biological Psychiatry, 2(1), 45-52, Elsevier Inc, DOI: 10.1016/j.bpsc.2016.08.006.
  • Holmes, S., Esterlis, I., Mazure, C., Lim, YY., Ames, D., Rainey-Smith, S., Martins, R., Salvado, O., Dore, V., Villemagne, V., Rowe, C., Laws, S., Masters, C., Maruff, P., Pietrzak, R., (2016), ?-Amyloid, APOE and BDNF Genotype, and Depressive and Anxiety Symptoms in Cognitively Normal Older Women and Men. American Journal of Geriatric Psychiatry, 24(12), 1191-1195, Elsevier B.V., DOI: 10.1016/j.jagp.2016.08.007.
  • Gupta, V., Doecke, J., Hone, E., Pedrini, S., Laws, S., Thambisetty, M., Bush, A., Rowe, C., Villemagne, V., Ames, D., Masters, C., Macaulay, SL., Rembach, A., Rainey-Smith, S., Martins, R., (2016), Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging. Alzheimers and Dementia: Diagnosis, Assessment & Disease Monitoring, 3(2016), 18-26, Elsevier Inc., DOI: 10.1016/j.dadm.2015.12.001.
  • Brown, B., Rainey-Smith, S., Villemagne, V., Weinborn, M., Bucks, R., Sohrabi, H., Laws, S., Taddei, K., Macaulay, SL., Ames, D., Fowler, C., Maruff, P., Masters, C., Rowe, C., Martins, R., (2016), The relationship between sleep quality and brain amyloid burden. Sleep, 39(5), 1063-1068, Westchester, USA, Associated Professional Sleep Societies,LLC, DOI: 10.5665/sleep.5756.
  • Porter, T., Bharadwaj, P., Groth, D., Paxman, A., Laws, S., Martins, R., Verdile, G., (2016), The Effects of Latrepirdine on Amyloid-? Aggregation and Toxicity. Journal of Alzheimer's Disease, 50(3), 895-905, Netherlands, IOS Press, DOI: 10.3233/JAD-150790.
  • Burnham, S., Bourgeat, P., Dore, V., Savage, G., Brown, B., Laws, S., Maruff, P., Salvado, O., Ames, D., Martins, R., Masters, C., Rowe, C., Villemagne, V., (2016), Clinical and cognitive trajectories in cognitively healthy elderly individuals with suspected non-Alzheimer's disease pathophysiology (SNAP) or Alzheimer's disease pathology: a longitudinal study. Lancet Neurology, 15(10), 1044-1053, London, UK, Lancet Publishing Group, DOI: 10.1016/S1474-4422(16)30125-9.
  • Lim, Y., Laws, S., Villemagne, V., Pietrzak, R., Porter, T., Ames, D., Fowler, C., Rainey-Smith, S., Snyder, P., Martins, R., Salvado, O., Bourgeat, P., Rowe, C., Masters, C., Maruff, P., (2016), A?-related memory decline in APOE ?4 non-carriers: Implications for Alzheimer?s disease. Neurology, 86(17), 1635-1642, Lippincott Williams and Wilkins, DOI: 10.1212/WNL.0000000000002604.
  • Burnham, S., Rowe, C., Baker, D., Bush, A., Doecke, JD., Faux, N., Laws, S., Martins, R., Maruff, P., Macaulay, S., Rainey-Smith, S., Savage, G., Ames, D., Masters, C., Wilson, W., Villemagne, V., (2016), Predicting Alzheimer disease from a blood-based biomarker profile. Neurology, 87(11), 1093-1101, Lippincott Williams and Wilkins, DOI: 10.1212/WNL.0000000000003094.
  • Lim, YY., Villemagne, V., Laws, S., Pietrzak, R., Ames, D., Fowler, C., Rainey-Smith, S., Snyder, P., Bourgeat, P., Martins, R., Salvado, O., Rowe, C., Masters, C., Maruff, P., (2016), Performance on the Cogstate Brief Battery Is Related to Amyloid Levels and Hippocampal Volume in Very Mild Dementia. Journal of Molecular Neuroscience, 60(3), 362-370, Springer New York LLC, DOI: 10.1007/s12031-016-0822-8.
  • Gardener, S., Sohrabi, H., Shen, K., Rainey-Smith, S., Weinborn, M., Bates, K., Shah, T., Foster, J., Lenzo, N., Salvado, O., Laske, C., Laws, S., Taddei, K., Martins, R., (2016), Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults. Journal of Alzheimer's Disease, 52(2), 661-672, Netherlands, IOS Press, DOI: 10.3233/JAD-151084.
  • Gupta, V., Wilson, A., Burnham, S., Hone, E., Pedrini, S., Laws, S., Lim, F., Rembach, A., Rainey-Smith, S., Ames, D., Cobiac, L., Macaulay, SL., Masters, C., Rowe, C., Bush, A., Martins, R., (2015), Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort. Alzheimer's Research and Therapy, 7(1), Article no.16, United Kingdom, BioMed Central Ltd., DOI: 10.1186/s13195-015-0105-6.
  • Pietrzak, RH., Lim, YY., Ames, D., Harrington, K., Restrepo, C., Martins, R., Rembach, A., Laws, S., Masters, CL., Villemagne, VL., Rowe, CC., Maruff, P., (2015), Trajectories of memory decline in preclinical Alzheimer's disease: Results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing. Neurobiology of Aging, 36(3), 1231-1238, United States, Elsevier , DOI: 10.1016/j.neurobiolaging.2014.12.015.
  • Thai, C., Lim, YY., Villemagne, VL., Laws, S., Ames, D., Ellis, KA., Rainey-Smith, S., Martins, R., Masters, CL., Rowe, CC., Maruff, P., Aibl Research Group, .., (2015), Amyloid-Related Memory Decline in Preclinical Alzheimer?s Disease is Dependent on APOE ?4 and is Detectable over 18-Months. PLoS One, 10(10), Article number e0139082, San Francisco, California, United States, Public Library of Science, DOI: 10.1371/journal.pone.0139082.
  • Li, Q., Villemagne, V., Doecke, J., Rembach, A., Sarros, S., Varghese, S., McGlade, A., Laughton, K., Pertile, K., Fowler, C., Rumble, R., Trounson, B., Taddei, K., Rainey-Smith, S., Laws, S., Robertson, J., Evered, L., Silbert, B., Ellis, K., Rowe, C., Macaulay, S., Darby, D., Martins, R., Ames, D., Masters, C., Collins, S., (2015), Alzheimer?s Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-? Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Journal of Alzheimer's Disease, 48(1), 175-187, Amsterdam, Netherlands, IOS Press, DOI: 10.3233/JAD-150247.
  • Rembach, A., Evered, L., Li, Q., Nash, T., Vidaurre, L., Fowler, CJ., Pertile, KK., Rumble, RL., Trounson, BO., Maher, S., Mooney, F., Farrow, M., Taddei, K., Rainey-Smith, S., Laws, S., Macaulay, SL., Wilson, W., Darby, DG., Martins, R., Ames, D., Collins, S., Silbert, B., Masters, CL., Doecke, JD., Aibl Research Group, .., (2015), Alzheimer's Disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology. Alzheimer's Research and Therapy, 7(2015), Article number 71, London, United Kingdom, BioMed Central Ltd., DOI: 10.1186/s13195-015-0157-7.
  • Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, Frontiers Research Foundation, DOI: 10.3389/fnagi.2015.00016.
  • Gu, B., Field, J., Duterte, S., Ou, A., Kilpatrick, T., Lechner-Scott, J., Scott, R., Lea, R., Taylor, B., Stankovich, J., Butzkueven, H., Gresle, M., Laws, S., Petrou, S., Hoffjan, S., Akkad, D., Graham, C., Hawkins, S., Glaser, A., Bedri, S., Hillert, J., Matute, C., Antiguedad, A., Consortium, A., Wiley, J., (2015), A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis. Human Molecular Genetics, 24(19), 5644-54, Oxford, United Kingdom, Oxford University Press, DOI: 10.1093/hmg/ddv278.
  • Lim, YY., Villemagne, V., Laws, S., Ames, D., Pietrzak, R., Ellis, K., Harrington, K., Bourgeat, P., Bush, A., Martins, R., Masters, C., Rowe, C., Maruff, P., (2014), Effect of BDNF Val66Met on memory decline and hippocampal atrophy in prodromal Alzheimer?s disease: A preliminary study. PLoS One, 9(1), Article no. e86498, Public Library of Science, DOI: 10.1371/journal.pone.0086498.
  • Rembach, A., Faux, N., Watt, A., Pertile, K., Rumble, R., Trounson, B., Fowler, C., Roberts, B., Perez, K., Li, Q., Laws, S., Taddei, K., Rainey-Smith, S., Robertson, J., Vandijck, M., Vanderstichele, H., Barnham, K., Ellis, K., Szoeke, C., Macaulay, L., Rowe, C., Villemagne, V., Ames, D., Martins, R., Bush, A., Masters, C., Aibl Research Group, T., (2014), Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's and Dementia, 10(1), 53-61, United States, Elsevier Science Inc., DOI: 10.1016/j.jalz.2012.12.006.
  • Lim, YY., Villemagne, VL., Laws, S., Pietrzak, RH., Snyder, PJ., Ames, D., Ellis, KA., Harrington, K., Rembach, A., Martins, R., Rowe, CC., Masters, CL., Maruff, P., (2014), APOE and BDNF polymorphisms moderate amyloid ?-related cognitive decline in preclinical Alzheimer's disease. Molecular Psychiatry, 20(11), 1322-1328, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2014.123.
  • Villemagne, V., Dore, V., Yates, P., Brown, B., Mulligan, R., Bourgeat, P., Veljanoski, R., Rainey-Smith, S., Ong, K., Rembach, A., Williams, R., Burnham, S., Laws, S., Salvado, O., Taddei, K., Macaulay, SL., Martins, R., Ames, D., Masters, C., Rowe, C., (2014), En Attendant Centiloid. Advances in Research, 2(12), 723-729, Online, Science Domain International, DOI: 10.9734/AIR/2014/11599.
  • Kanyenda, L., Verdile, G., Martins, R., Meloni, B., Chieng, J., Mastaglia, F., Laws, S., Anderton, R., Boulos, S., (2014), Is cholesterol and amyloid-? stress induced CD147 expression a protective response? Evidence that extracellular cyclophilin a mediated neuroprotection is reliant on CD147. Journal of Alzheimer's Disease, 39(3), 545-546, Netherlands, IOS Press, DOI: 10.3233/JAD-131442.
  • Brown, B., Bourgeat, P., Peiffer, J., Burnham, S., Laws, S., Rainey-Smith, S., Bartres-Faz, D., Villemagne, V., Taddei, K., Rembach, A., Bush, A., Ellis, K., Macaulay, SL., Rowe, C., Ames, D., Masters, C., Maruff, P., Martins, R., (2014), Influence of BDNF Val66Met on the relationship between physical activity and brain volume. Neurology, 83(15), 1345-52, Lippincott Williams and Wilkins, DOI: 10.1212/WNL.0000000000000867.
  • Sharman, M., Moussavi Nik, S., Chen, M., Ong, D., Wijaya, L., Laws, S., Taddei, K., Newman, M., Lardelli, M., Martins, R., Verdile, G., (2013), The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes. PLoS One, 8(6), e66235.
  • Lim, YY., Villemagne, V., Laws, S., Ames, D., Pietrzak, R., Ellis, K., Harrington, K., Bourgeat, P., Salvado, O., Darby, D., Snyder, P., Bush, A., Martins, R., Masters, C., Rowe, C., Nathan, P., Maruff, P., (2013), BDNF Val66Met, Abeta amyloid, and cognitive decline in preclinical Alzheimer's disease. Neurobiology of Aging, 34(11), 2457-2464, United States, Elsevier.
  • Burnham, S., Faux, N., Wilson, W., Laws, S., Ames, D., Bedo, J., Bush, A., Doecke, J., Ellis, K., Head, R., Jones, G., Kiiveri, H., Martins, R., Rembach, A., Rowe, C., Salvado, O., Macaulay, SL., Masters, C., Villemagne, V., (2013), A blood-based predictor for neocortical A-beta burden in Alzheimer's disease: results from the AIBL study. Molecular Psychiatry, 19(2014), 519-526, United Kingdom, Nature Publishing Group.
  • Martins, I., Lim, F., Wilson, A., Laws, S., Martins, R., (2013), The acceleration of aging and Alzheimer?s disease through the biological mechanisms behind obesity and type II diabetes. Health, 5(5), 913-920, United States of America, Scientific Research Publishing, Inc., DOI: 10.4236/health.2013.55121.
  • Martins, I., Wilson, A., Lim, F., Laws, S., Fuller, S., Martins, R., (2012), Sirtuin-1 mediates the obesity induced risk of common degenerative diseases: Alzheimer?s disease, coronary artery disease and type 2 diabetes. Health, 4(12A), 1448-1456, United States, Scientific Research Publishing, Inc., DOI: 10.4236/health.2012.412A209.
  • Sohrabi, H., Bates, K., Weinborn, M., Johnston, A., Bahramian, A., Taddei, K., Laws, S., Rodrigues, M., Morici, M., Howard, M., Martins, G., Mackay-Sim, A., Gandy, S., Martins, R., (2012), Olfactory discrimination predicts cognitive decline amongst community-dwelling older adults. Translational Psychiatry , 2(2012), art. no. e118 , Nature Publishing Group, DOI: 10.1038/tp.2012.43.
  • Lau, S., Bates, K., Sohrabi, H., Rodrigues, M., Martins, G., Dhaliwal, S., Taddei, K., Laws, S., Martins, I., Mastaglia, F., Foster, J., Phillips, J., Martins, R., (2012), Functional effects of genetic polymorphism in inflammatory genes in subjective memory complainers. Neurobiology of Aging, 33(6), 1054-1056, United States, Elsevier, DOI: 10.1016/j.neurobiolaging.2010.09.003.
  • Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, L., Szoeke, C., Rowe, C., Martins, R., (2012), Physical activity and amyloid-? plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18(8), 875-881, United Kingdom, Nature Publishing Group.
  • Doecke, J., Laws, S., Faux, N., Wilson, W., Burnham, S., Lam, P., Mondal, A., Bedo, J., Bush, A., Brown, B., De Ruyck, K., Ellis, K., Fowler, C., Gupta, V., Head, R., Macaulay, SL., Pertile, K., Rowe, C., Rembach, A., Rodrigues, M., Rumble, R., Szoeke, C., Taddei, K., Taddei, T., Trounson, B., Ames, D., Masters, C., Martins, R., (2012), Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease. Archives of Neurology, 69(10), 1318-1325, United States, American Medical Association, DOI: 10.1001/archneurol.2012.1282.
  • Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoeke, C., Taddei, K., Villemagne, V., Martins, R., (2012), Associations between gonadotropins, testosterone and ? amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry, 19(1), 69-75, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2012.147.
  • Guo, LH., Westerteicher, C., Wang, X., Kratzer, M., Tsolakidou, A., Jiang, M., Grimmer, T., Laws, S., Alexopoulos, P., Bujo, H., Kurz, A., Perneczky, R., (2012), SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer's disease. European Archives of Psychiatry and Clinical Neuroscience, 262(6), 529-534, DOI: 10.1007/s00406-012-0295-x.
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