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Dr Manshu Song

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Staff Member Details
Email: m.song@ecu.edu.au
ORCID iD: https://orcid.org/0000-0003-1433-7192

Qualifications

  • Doctor of Natural Science Microbiology, China (excludes SARs and Taiwan), 2005.

Research Outputs

2026

Journal Articles

  • He, J., Peng, F., Qu, Y., Zhao, Y., Li, Y., Zhou, Y., Guo, C., Li, X., Song, M., Chen, X., Hong, Q., Wang, W. (2026). Dysregulation of argininosuccinate synthase 1, phosphoenolpyruvate carboxykinase 1, and carbonyl reductase 3: Key arginine–proline metabolic mediators in mesangioproliferative glomerulopathies. International Journal of Biological Macromolecules, 337(2026), article number 149479. https://doi.org/10.1016/j.ijbiomac.2025.149479.
  • Handels, R., Hoevenaar-Blom, M., Song, M., Brayne, C., Van Charante, EM., Matthews, FE., Xu, J., Jönsson, L., Coley, N., Brooks, R., Jian, X., Qin, T., Wang, Y., Wang, W., Richard, E., Wimo, A. (2026). Prevention of dementia using mobile phone applications (PRODEMOS) – a health-economic cost-utility analysis in people aged 55–75 years with low socio-economic status. Journal of Prevention of Alzheimer's Disease, 13(5), article number 100526. https://doi.org/10.1016/j.tjpad.2026.100526.

2025

Journal Articles

  • Ronca, D., Mesquita, LO., Oliveira, D., Figueiredo, AC., Wen, J., Song, M., De Carvalho, KM. (2025). Excess weight is associated with neurological and neuropsychiatric symptoms in post-COVID-19 condition: A systematic review and meta-analysis. PLoS One, 20(45782), article number e0314892. https://doi.org/10.1371/journal.pone.0314892.
  • He, Z., Liu, M., Ying, P., Song, M., Tan, X. (2025). Diagnostic accuracy of electrocardiogram algorithms for differentiating left from right outflow tract ventricular arrhythmia: A systematic review and network meta-Analysis. Heart, 2025(Article in press), article number heartjnl-2025-325916. https://doi.org/10.1136/heartjnl-2025-325916.
  • Xu, X., Chen, Z., Song, M., Hou, Z., Balmer, L., Zhou, C., Huang, Y., Hou, H., Wang, W., Lin, L. (2025). Profiling of IgG N-glycosylation for axial spondyloarthritis and other rheumatic diseases. Arthritis Research and Therapy, 27(1), Article number 37. https://doi.org/10.1186/s13075-025-03505-y.
  • Zhang, J., Hoevenaar-Blom, MP., Jian, X., Hou, H., Ge, S., Brayne, C., Eggink, E., Hafdi, M., He, M., Wang, G., Wang, W., Zhang, W., Yu, Y., Niu, Y., Lyu, J., Song, L., Wang, W., Wang, Y., Moll Van Charante, EP., Song, M. (2025). Implementation of a coach-supported mHealth intervention for dementia prevention in China: a qualitative study among Chinese participants and coaches in the PRODEMOS trial. Journal of Global Health, 15(2025), article number 4036. https://doi.org/10.7189/JOGH.15.04036.
  • Lindhout, JE., Hoevenaar-Blom, MP., Van Dalen, JW., Song, M., Lin, D., Wang, W., Richard, E., Moll Van Charante, EP., Van Middelaar, T. (2025). Association between hypertension and dementia risk in low- and middle-income countries: A systematic review. The Journal of Aging Research & Lifestyle(JARCP), 14(2025), article number 100027. https://doi.org/10.1016/j.jarlif.2025.100027.
  • Chen, S., Balmer, L., Lin, K., Cao, W., Huang, Z., Chen, X., Song, M., Chen, Y. (2025). IgG N-glycosylation contributes to different severities of insulin resistance: implications for 3P medical approaches. EPMA Journal, 16(2), 419-435. https://doi.org/10.1007/s13167-025-00410-x.
  • Chen, Z., Chu, J., Wang, J., Cai, C., Lu, X., Song, M., Balmer, L., Wang, W., Tan, X. (2025). Horizontal QRS axis predicts response to cardiac resynchronization therapy in heart failure patients with left bundle branch block. Heart Rhythm, 22(7), e122-e131. https://doi.org/10.1016/j.hrthm.2024.11.011.
  • He, Z., Zhang, Q., Song, M., Tan, X., Wang, W. (2025). Four overlooked errors in ROC analysis: how to prevent and avoid. BMJ Evidene-Based Medicine, 30(3), 208-211. https://doi.org/10.1136/bmjebm-2024-113078.

2024

Book Chapters

Journal Articles

  • Chen, Z., Xu, X., Song, M., Lin, L. (2024). Crosstalk Between Cytokines and IgG N-Glycosylation: Bidirectional Effects and Relevance to Clinical Innovation for Inflammatory Diseases. OMICS: A Journal of Integrative Biology, 28(12), 608-619. https://doi.org/10.1089/omi.2024.0176.
  • Tian, C., Li, X., Zhang, H., He, J., Zhou, Y., Song, M., Yang, P., Tan, X. (2024). Differences in IgG afucosylation between groups with and without carotid atherosclerosis. BMC Cardiovascular Disorders, 24(1), Article number 612. https://doi.org/10.1186/s12872-024-04296-x.
  • Xu, R., Balmer, L., Chen, G., Song, M. (2024). Role of N-Glycosylation in Gastrointestinal Cancers. OMICS: A Journal of Integrative Biology, 28(12), 596-607. https://doi.org/10.1089/omi.2024.0174.
  • Rapčan, B., Song, M., Frkatović-Hodžić, A., Pribić, T., Vuk, J., Beletić, A., Hanić, M., Jurić, J., Tominac, P., Milas, J., Ivić, V., Viland, S., Bonet, S., Šego, B., Heffer, M., Wang, W., Snyder, MP., Lauc, G. (2024). Glycan clock of ageing-analytical precision and time-dependent inter- and i-individual variability. GeroScience, 46(6), 5781-5796. https://doi.org/10.1007/s11357-024-01239-4.
  • Oh, S., Cao, W., Song, M. (2024). Twin Scholarships of Glycomedicine and Precision Medicine in Times of Single-Cell Multiomics. Diabetes/Metabolism Research and Reviews, 28(7), 319-323. https://doi.org/10.1089/omi.2024.0111.
  • Moll Van Charante, E., Hoevenaar-Blom, M., Song, M., Andrieu, S., Barnes, L., Birck, C., Brooks, R., Coley, N., Eggink, E., Georges, J., Hafdi, M., Van Gool, W., Handels, R., Hou, H., Lyu, J., Niu, Y., Song, L., Wang, W., Wang, Y., Wimo, A., Yu, Y., Zhang, J., Zhang, W., Brayne, C., Wang, W., Richard, E. (2024). Prevention of dementia using mobile phone applications (PRODEMOS): a multinational, randomised, controlled effectiveness–implementation trial. The Lancet Healthy Longevity, 5(6), e431-e442. https://doi.org/10.1016/S2666-7568(24)00068-0.
  • Zhou, C., Balmer, L., Song, M., Wu, K., Wang, W., Wang, H. (2024). CircPVT1 promotes migration and invasion by regulating miR-490-5p/HAVCR2 axis in osteosarcoma cells. Journal of Cellular and Molecular Medicine, 28(8), Article number e18269. https://doi.org/10.1111/jcmm.18269.
  • Zhou, C., Balmer, L., Song, M., Mahara, G., Wu, K., Wang, W., Wang, H. (2024). Identification of circRNA biomarkers in osteosarcoma: An updated systematic review and meta-analysis. Non-coding RNA Research, 9(2), 341-349. https://doi.org/10.1016/j.ncrna.2024.01.007.

2023

Journal Articles

  • Ayubi, E., Khazaei, S., Borzouei, S., Soltanian, AR., Ghelichkhani, S., Karbin, F., Yan, Y., Song, M., Tian, C., Zhang, W., Sun, J., Wang, W. (2023). Validity and reliability of the Persian version of the Suboptimal Health Status Questionnaire among university staff in Iran. Journal of Global Health, 13(2023), Article number 04162. https://doi.org/10.7189/jogh.13.04162.
  • Lan, Y., Chen, G., Wu, D., Ding, X., Huang, Z., Wang, X., Balmer, L., Li, X., Song, M., Wang, W., Wu, S., Chen, Y. (2023). Temporal relationship between atherogenic dyslipidemia and inflammation and their joint cumulative effect on type 2 diabetes onset: a longitudinal cohort study. BMC Medicine, 21(1), Article number 31. https://doi.org/10.1186/s12916-023-02729-6.
  • Lan, Y., Wu, D., Cai, Z., Xu, Y., Ding, X., Wu, W., Lan, S., Chen, L., Guo, Z., Balmer, L., Li, X., Song, M., Wu, S., Gao, J., Wang, W., Chen, Y. (2023). Supra-additive effect of chronic inflammation and atherogenic dyslipidemia on developing type 2 diabetes among young adults: a prospective cohort study. Cardiovascular Diabetology, 22(1), Article number 181. https://doi.org/10.1186/s12933-023-01878-5.
  • Wang, BY., Song, M., Zhang, J., Meng, XN., Xing, WJ., Wang, Y. (2023). A Nested Case-Control Study To Explore The Association Between Immunoglobulin G N-Glycans And Ischemic Stroke*. Biomedical and Environmental Sciences, 36(5), 389-396. https://doi.org/10.3967/bes2023.048.
  • Jurić,, J., Peng, H., Song, M., Vučković, F., Šimunović, J., Trbojević-Akmačić, I., Wang, Y., Liu, J., Gao, Q., Wang, H., Chu, Q., Pezer, M., Wang, W., Lauc, G. (2023). Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle. Engineering, 26(July 2023), 108-118. https://doi.org/10.1016/j.eng.2022.10.020.
  • Meng, X., Cao, W., Liu, D., Elijah, I., Xing, W., Hou, H., Xu, X., Song, M., Wang, Y. (2023). Bidirectional Causality Between Immunoglobulin G N-Glycosylation and Metabolic Traits: A Mendelian Randomization Study. Engineering, 26(2023), 74-88. https://doi.org/10.1016/j.eng.2022.11.004.

2022

Journal Articles

  • Wang, B., Liu, D., Song, M., Wang, W., Guo, B., Wang, Y. (2022). Immunoglobulin G N-glycan, inflammation and type 2 diabetes in East Asian and European populations: a Mendelian randomization study. Molecular Medicine, 28(1), Article number 114. https://doi.org/10.1186/s10020-022-00543-z.
  • Meng, X., Wang, B., Xu, X., Song, M., Hou, H., Wang, W., Wang, Y. (2022). Glycomic biomarkers are instrumental for suboptimal health status management in the context of predictive, preventive, and personalized medicine. EPMA Journal, 13(2), 195-207. https://doi.org/10.1007/s13167-022-00278-1.
  • Guo, Z., Meng, R., Zheng, Y., Li, X., Zhon, Z., Yu, L., Tang, Q., Zhao, Y., Garcia, M., Tan, Y., Song, M., Balmer, L., Wen, J., Hou, H., Tan, X., Wang, W. (2022). Translation and cross-cultural validation of a precision health tool, the Suboptimal Health Status Questionnaire-25, in Korean. Journal of Global Health, 12(1 October 2022), Article Number 04077. https://doi.org/10.7189/jogh.12.04077.
  • Zhang, X., Cong, R., Geng, T., Zhang, J., Liu, D., Tian, Q., Meng, X., Song, M., Wu, L., Zheng, D., Wang, W., Wang, B., Wang, Y. (2022). Assessment of the Causal Effect of IgG N-Glycosylation Level on Risk of Dementia: A 2-Sample Mendelian Randomization Study. Journal of Alzheimer's Disease, 88(4), 1435-1441. https://doi.org/10.3233/JAD-220074.
  • Zhang, X., Wang, B., Geng, T., Liu, D., Tian, Q., Meng, X., Zhang, Q., Jiang, M., Zhang, Y., Song, M., Wang, W., Wang, Y., Wang, B. (2022). Causal associations between COVID-19 and atrial fibrillation: A bidirectional Mendelian randomization study. Nutrition Metabolism and Cardiovascular Diseases, 32(4), 1001-1009. https://doi.org/10.1016/j.numecd.2021.11.010.
  • Zhang, J., Eggink, E., Zhang, X., Li, X., Jiang, B., Liu, H., Ge, S., Zhang, W., Lyu, J., Niu, Y., Yu, Y., Hou, H., Xu, X., Ye, X., Wang, W., Terlou, R., Richard, E., Wang, W., Wang, Y., Moll Van Charante, E., Song, M. (2022). Needs and views on healthy lifestyles for the prevention of dementia and the potential role for mobile health (mHealth) interventions in China: a qualitative study. BMJ Open, 12(11), Article Number e061111. https://doi.org/10.1136/bmjopen-2022-061111.
  • Liu, D., Meng, X., Tian, Q., Cao, W., Fan, X., Wu, L., Song, M., Meng, Q., Wang, W., Wang, Y. (2022). Vitamin D and Multiple Health Outcomes: An Umbrella Review of Observational Studies, Randomized Controlled Trials, and Mendelian Randomization Studies. Advances in Nutrition, 13(4), 1044-1062. https://doi.org/10.1093/advances/nmab142.

2021

Journal Articles

  • Wang, B., Zhang, X., Liu, D., Zhang, J., Cao, M., Tian, X., Maranga, I., Meng, X., Tian, Q., Tian, F., Cao, W., Wang, W., Song, M., Wang, Y. (2021). The Role of C-Reactive Protein and Fibrinogen in the Development of Intracerebral Hemorrhage: A Mendelian Randomization Study in European Population. Frontiers in Genetics, 12(4 February 2021), Article 608714. https://doi.org/10.3389/fgene.2021.608714.
  • Eggink, E., Hafdi, M., Hoevenaar-Blorn, M., Song, M., Andrieu, S., Barnes, L., Birck, C., Brooks, R., Coley, N., Ford, E., Georges, J., Van Der Groep, A., Van Gool, W., Handels, R., Hou, H., Li, D., Liu, H., Lyu, J., Van Marwijk, H., Van Der Meijden, M., Niu, Y., Sadhwani, S., Wang, W., Wang, Y., Wimo, A., Ye, X., Yu, Y., Zeng, Q., Zhang, W., Wang, W., Brayne, C., Moll Van Charante, E., Richard, E. (2021). Prevention of dementia using mobile phone applications (PRODEMOS): protocol for an international randomised controlled trial. BMJ Open, 11(6), Article number e049762. https://doi.org/10.1136/bmjopen-2021-049762.
  • Wang, H., Tian, Q., Zhang, J., Liu, H., Zhang, J., Cao, W., Zhang, X., Li, X., Wu, L., Song, M., Kong, Y., Wang, W., Wang, Y. (2021). Blood transcriptome profiling as potential biomarkers of suboptimal health status: potential utility of novel biomarkers for predictive, preventive, and personalized medicine strategy. EPMA Journal, 12(2), 103-115. https://doi.org/10.1007/s13167-021-00238-1.
  • Li, X., Wang, H., Zhu, Y., Cao, W., Song, M., Wang, Y., Hou, H., Lang, M., Guo, X., Tan, X., Han, J., Wang, W. (2021). Heritability Enrichment of Immunoglobulin G N-Glycosylation in Specific Tissues. Frontiers in Immunology, 12(3 November 2021), article number 741705. https://doi.org/10.3389/fimmu.2021.741705.
  • Meng, X., Song, M., Vilaj, M., Štambuk , J., Dolikun, M., Zhang, J., Liu, D., Wang, H., Zhang, X., Zhang, J., Cao, W., Momčilović , A., Trbojević-Akmačić , I., Li, X., Zheng, D., Wu, L., Guo, X., Wang, Y., Lauc, G., Wang, W. (2021). Glycosylation of IgG Associates with Hypertension and Type 2 Diabetes Mellitus Comorbidity in the Chinese Muslim Ethnic Minorities and the Han Chinese. Journal of Personalized Medicine, 11(7), Article number 614. https://doi.org/10.3390/jpm11070614.
  • Hafdi, M., Eggink, E., Hoevenaar-Blom, M., Witvliet, MP., Andrieu, S., Barnes, L., Brayne, C., Brooks, R., Coley, N., Georges, J., Van Der Groep, A., Van Marwijk, H., Van Der Meijden, M., Song, L., Song, M., Wang, Y., Wang , W., Wang, W., Wimo, A., Ye, X., Moll Van Charante, E., Richard, E. (2021). Design and Development of a Mobile Health (mHealth) Platform for Dementia Prevention in the Prevention of Dementia by Mobile Phone Applications (PRODEMOS) Project. Frontiers in Neurology, 12(Dec 2021), Article number 733878. https://doi.org/10.3389/fneur.2021.733878.

2020

Journal Articles

  • Zhang, X., Wang, A., Zhang, J., Singh, M., Liu, D., Zuo, Y., Wu, L., Song, M., Wang, W., Feigin, V., Wang, Y., Zheng, D. (2020). Association of plasma C-reactive protein with ischaemic stroke: a Mendelian randomization study. European Journal of Neurology, 27(3), 565-571. https://doi.org/10.1111/ene.14113.
  • Cao, W., Zheng, D., Wang, G., Zhang, J., Ge, S., Singh, M., Wang, H., Song, M., Li, D., Wang, W., Xu, X., Wang, Y. (2020). Modelling biological age based on plasma peptides in Han Chinese adults. Aging, 12(11), 10676-10686. https://doi.org/10.18632/aging.103286.
  • Wang, H., Tian, Q., Zhang, J., Liu, H., Zhang, X., Cao, W., Zhang, J., Anto, E., Li, X., Wang, X., Liu, D., Zheng, Y., Guo, Z., Wu, L., Song, M., Wang, Y., Wang, W. (2020). Population-based case-control study revealed metabolomic biomarkers of suboptimal health status in Chinese population—potential utility for innovative approach by predictive, preventive, and personalized medicine. EPMA Journal, 11(2), 147-160. https://doi.org/10.1007/s13167-020-00200-7.
  • Cao, W., Zheng, D., Zhang, J., Wang, A., Liu, D., Zhang, J., Singh, M., Maranga, I., Cao, M., Wu, L., Song, M., Wang, W., Wang, Y. (2020). Association between telomere length in peripheral blood leukocytes and risk of ischemic stroke in a Han Chinese population: A linear and non-linear Mendelian randomization analysis. Journal of Translational Medicine, 18(1), Article number 385. https://doi.org/10.1186/s12967-020-02551-1.
  • Sun, Q., Xu, X., Zhang, J., Sun, M., Tian, Q., Li, Q., Cao, W., Zhang, X., Wang, H., Liu, J., Zhang, J., Meng, X., Wu, L., Song, M., Liu, H., Wang, W., Wang, Y. (2020). Association of suboptimal health status with intestinal microbiota in Chinese youths. Journal of Cellular and Molecular Medicine, 24(2), 1837-1847. https://doi.org/10.1111/jcmm.14880.
  • Molan, A., Nosaka, K., Hunter, M., Xiang, J., Meng, X., Song, M., Wang, W. (2020). First Age- and Gender-Matched Case-Control Study in Australia Examining the Possible Association between Toxoplasma gondii Infection and Type 2 Diabetes Mellitus: The Busselton Health Study. Journal of Parasitology Research, 2020(2020), Article number 3142918. https://doi.org/10.1155/2020/3142918.
  • Zhang, X., Tian, Q., Liu, D., Geng, T., Xu, X., Ge, S., Zheng, D., Wu, L., Song, M., Hou, H., Wang, W., Wang, Y. (2020). Causal association of circulating cholesterol levels with dementia: a mendelian randomization meta-analysis. Translational Psychiatry, 10(1), Article number 145. https://doi.org/10.1038/s41398-020-0822-x.
  • Štambuk, J., Nakić, N., Vučković, F., Pučić-Baković, M., Razdorov, G., Trbojević-Akmačić, I., Novokmet, M., Keser, T., Vilaj, M., Štambuk, T., Gudelj, I., Šimurina, M., Song, M., Wang, H., Peričić Salihović, M., Campbell, H., Rudan, I., Kolčić, I., Eller, LA., McKeigue, P., Robb, M., Halfvarson, J., Kurtoglu, M., Annese, V., Škarić-Jurić, T., Molokhia, M., Polašek, O., Hayward, C., Kibuuka, H., Thaqi, K., Primorac, D., Gieger, C., Nitayaphan, S., Spector, T., Wang, Y., Tillin, T., Chaturvedi, N., Wilson, J., Schanfield, M., Filipenko, M., Wang, W., Lauc, G. (2020). Global variability of the human IgG glycome. Aging, 12(15), 15222-15259. https://doi.org/10.18632/aging.103884.

2019

Journal Articles

  • Cao, W., Li, X., Zhang, X., Zhang, J., Sun, Q., Xu, X., Sun, M., Tian, Q., Li, Q., Wang, H., Liu, J., Meng, X., Wu, L., Song, M., Hou, H., Wang, Y., Wang, W. (2019). No Causal Effect of Telomere Length on Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study. Cells, 8(2), Article number 159. https://doi.org/10.3390/cells8020159.
  • Ge, S., Xu, X., Zhang, J., Hou, H., Wang, H., Liu, D., Zhang, X., Song, M., Li, D., Zhou, Y., Wang, Y., Wang, W. (2019). Suboptimal health status as an independent risk factor for type 2 diabetes mellitus in a community-based cohort: the China suboptimal health cohort study. EPMA Journal, 10(1), 65-72. https://doi.org/10.1007/s13167-019-0159-9.
  • Russell, A., Kepka, A., Trbojevic-Akmacic, I., Ugrina, I., Song, M., Hui, J., Hunter, M., Laws, S., Lauc, G., Wang, W. (2019). Increased central adiposity is associated with pro-inflammatory immunoglobulin G N-glycans. Immunobiology, 224(1), 110-115. https://doi.org/10.1016/j.imbio.2018.10.002.
  • Liu, D., Li, Q., Dong, J., Li, D., Xu, X., Xing, W., Zhang, X., Cao, W., Hou, H., Wang, H., Song, M., Tao, L., Kang, X., Meng, Q., Wang, W., Guo, X., Wang, Y. (2019). The Association Between Normal BMI With Central Adiposity And Proinflammatory Potential Immunoglobulin G N-Glycosylation. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 12(November 2019), 2373-2385. https://doi.org/10.2147/DMSO.S216318.
  • Wang, H., Li, X., Wang, X., Liu, D., Zhang, X., Cao, W., Zheng, Y., Guo, Z., Li, D., Xing, W., Hou, H., Wu, L., Song, M., Zhong, Z., Wang, Y., Tan, X., Lauc, G., Wang, W. (2019). Next-Generation (Glycomic) Biomarkers for Cardiometabolic Health: A Community-Based Study of Immunoglobulin G N-Glycans in a Chinese Han Population. OMICS: A Journal of Integrative Biology, 23(12), 649-659. https://doi.org/10.1089/omi.2019.0099.
  • Liu, J., Dolikun, M., Stambuk, J., Trbojevic-Akmacic, I., Zhang, J., Zhang, J., Wang, H., Meng, X., Razdorov, G., Menon, D., Zheng, D., Wu, L., Wang, Y., Song, M., Lauc, G., Wang, W. (2019). Glycomics for Type 2 Diabetes Biomarker Discovery: Promise of Immunoglobulin G Subclass-Specific Fragment Crystallizable N-glycosylation in the Uyghur Population. OMICS: A Journal of Integrative Biology, 23(12), 640-648. https://doi.org/10.1089/omi.2019.0052.
  • Hou, H., Xu, X., Sun, F., Zhang, X., Dong, H., Wang, L., Ge, S., An, K., Sun, Q., Li, Y., Cao, W., Song, M., Hu, S., Xing, W., Wang, W., Li, D., Wang, Y. (2019). Hyperuricemia is Associated with Immunoglobulin G N-Glycosylation: A Community-Based Study of Glycan Biomarkers. OMICS: A Journal of Integrative Biology, 23(12), 660-667. https://doi.org/10.1089/omi.2019.0004.
  • Li, X., Wang, H., Russell, A., Cao, W., Wang, X., Ge, S., Zheng, Y., Guo, Z., Hou, H., Song, M., Yu, X., Wang, Y., Hunter, M., Roberts, P., Lauc, G., Wang, W. (2019). Type 2 Diabetes Mellitus is Associated with the Immunoglobulin G N-Glycome through Putative Proinflammatory Mechanisms in an Australian Population. OMICS: A Journal of Integrative Biology, 23(12), 631-639. https://doi.org/10.1089/omi.2019.0075.
  • Liu, D., Li, Q., Zhang, X., Wang, H., Cao, W., Li, D., Xing, W., Song, M., Wang, W., Meng, Q., Wang, Y. (2019). Systematic Review: Immunoglobulin G N-Glycans as Next-Generation Diagnostic Biomarkers for Common Chronic Diseases. OMICS: A Journal of Integrative Biology, 23(12), 607-614. https://doi.org/10.1089/omi.2019.0032.

2018

Journal Articles

  • Peng, H., Zhao, P., Liu, J., Zhang, J., Zhang, J., Wang, Y., Wu, L., Song, M., Wang, W. (2018). Novel Epigenomic Biomarkers of Male Infertility Identified by Methylation Patterns of CpG Sites Within Imprinting Control Regions of H19 and SNRPN Genes. OMICS: A Journal of Integrative Biology, 22(5), 354-364. https://doi.org/10.1089/omi.2018.0019.
  • Liu, D., Chu, X., Wang, H., Dong, J., Ge, S., Zhao, Z., Peng, H., Sun, M., Wu, L., Song, M., Guo, X., Meng, Q., Wang, Y., Lauc, G., Wang, W. (2018). The changes of immunoglobulin G N‑glycosylation in blood lipids and dyslipidaemia. Journal of Translational Medicine, 16(1), Article no.235. https://doi.org/10.1186/s12967-018-1616-2.
  • Ge, S., Wang, Y., Song, M., Li, X., Yu, X., Wang, H., Wang, J., Zeng, Q., Wang, W. (2018). Type 2 Diabetes Mellitus: Integrative Analysis of Multiomics Data for Biomarker Discovery. OMICS: A Journal of Integrative Biology, 22(7), 514-523. https://doi.org/10.1089/omi.2018.0053.
  • Liu, D., Zhao, Z., Wang, A., Ge, S., Wang, H., Zhang, X., Sun, Q., Cao, W., Sun, M., Wu, L., Song, M., Zhou, Y., Wang, W., Wang, Y. (2018). Ischemic stroke is associated with the pro-inflammatory potential of N-glycosylated immunoglobulin G. Journal of Neuroinflammation, 15(1), Article no 123. https://doi.org/10.1186/s12974-018-1161-1.
  • Liu, J., Dolikun, M., Stambuk, J., Trbojević-Akmačić, I., Zhang, J., Wang, H., Zheng, D., Zhang, X., Peng, H., Zhao, Z., Liu, D., Sun, Y., Sun, Q., Li, Q., Zhang, J., Sun, M., Cao, W., Momčilović, A., Razdorov, G., Wu, L., Russell, A., Wang, Y., Song, M., Lauc, G., Wang, W. (2018). The association between subclass-specific IgG Fc N-glycosylation profiles and hypertension in the Uygur, Kazak, Kirgiz, and Tajik populations. Journal of Human Hypertension, 32(8-9), 555-563. https://doi.org/10.1038/s41371-018-0071-0.

2017

Journal Articles

  • Dong, H., Wang, Y., Zou, Z., Chen, L., Shen, C., Xu, S., Zhang, J., Zhao, F., Ge, S., Gao, Q., Hu, H., Song, M., Wang, W. (2017). Abnormal methylation of imprinted genes and cigarette smoking: assessment of their association with the risk of male infertility. Reproductive Sciences, 24(1), 114-123. https://doi.org/10.1177/1933719116650755.
  • Alzain, MA., Otieno, AC., Zhang, J., Fang, H., Zhao, Z., Guo, X., Song, M., Zhou, Y., Chang, N., Wang, Y., Wang, W. (2017). Telomere Length and Accelerated Biological Aging in the China Suboptimal Health Cohort: A Case–Control Study. OMICS: A Journal of Integrative Biology, 21(6), 333-339. https://doi.org/10.1089/omi.2017.0050.
  • Adua, E., Russell, A., Roberts, P., Wang, Y., Song, M., Wang, W. (2017). Innovation Analysis on Postgenomic Biomarkers: Glycomics for Chronic Diseases. OMICS: A Journal of Integrative Biology, 21(4), 183-196. https://doi.org/10.1089/omi.2017.0035.
  • Wang, Y., Liu, X., Qiu, J., Wang, H., Liu, D., Zhao, Z., Song, M., Song, Q., Wang, X., Zhou, Y., Wang, W. (2017). Association between ideal cardiovascular health metrics and suboptimal health status in Chinese population. Scientific Reports, 7(1), Article number 14975. https://doi.org/10.1038/s41598-017-15101-5.
  • Gao, Q., Dolikun, M., Stambuk, J., Wang, H., Zhao, F., Yiliham, N., Wang, Y., Trbojevic-Akmacic, I., Zhang, J., Fang, H., Sun, Y., Peng, H., Zhao, Z., Liu, D., Liu, J., Li, Q., Sun, Q., Wu, L., Lauc, G., Wang, W., Song, M. (2017). Immunoglobulin G N-Glycans as Potential Postgenomic Biomarkers for Hypertension in the Kazakh Population. OMICS: A Journal of Integrative Biology, 21(7), 380-389. https://doi.org/10.1089/omi.2017.0044.
  • Fang, H., Chu, Q., Zhang, J., Wang, H., Yu, X., Ge, S., Song, M., Wu, L., Lang, M., Chang, N., Wang, Y., Wang, W. (2017). Human CAP10-Like protein 46 kDa gene promotes malignancy in colorectal cancer. OMICS: A Journal of Integrative Biology, 21(5), 266-274. https://doi.org/10.1089/omi.2017.0037.
  • Meng, Q., Ge, S., Yan, W., Li, R., Dou, J., Wang, H., Wang, B., Ma, Q., Zhou, Y., Song, M., Yu, X., Wang, H., Yang, X., Liu, F., Alzain, MA., Yan, Y., Zhang, L., Wu, L., Zhao, F., He, Y., Guo, X., Chen, F., Xu, W., Garcia, M., Menon, D., Wang, Y., Mu, Y., Wang, W. (2017). Screening for potential serum-based proteomic biomarkers for human type 2 diabetes mellitus using MALDI-TOF MS. Proteomics: Clinical Applications, 11(3-4), Article number 1600079. https://doi.org/10.1002/prca.201600079.

2016

Journal Articles

  • Wang, Y., Klaric, L., Yu, X., Thaqi, K., Dong, J., Novokmet, M., Wilson, J., Polasek, O., Liu, Y., Kristic, J., Ge, S., Pucic-Bakovic, M., Wu, L., Zhou, Y., Ugrina, L., Song, M., Zhang, J., Guo, X., Zeng, Q., Rudan, L., Campbell, H., Aulchenko, Y., Lauc, G., Wang, W. (2016). The Association Between Glycosylation of Immunoglobulin G and Hypertension. Medicine, 95(17), Article no. e3379. https://doi.org/10.1097/MD.0000000000003379.
  • Yu, X., Wang, Y., Kristic, J., Dong, J., Chu, X., Ge, S., Wang, H., Fang, H., Gao, Q., Liu, D., Zhao, Z., Peng, H., Bakovic, M., Wu, L., Song, M., Rudan, I., Campbell, H., Lauc, G., Wang, W. (2016). Profiling IgG N-glycans as potential biomarker of chronological and biological ages: A community-based study in a Han Chinese population. Medicine, 95(28), e4112. https://doi.org/10.1097/MD.0000000000004112.
  • Sebastian, A., Alzain, M., Asweto, C., Song, H., Cui, L., Yu, X., Ge, S., Dong, H., Rao, P., Wang, H., Fang, H., Gao, Q., Zhang, J., He, D., Guo, X., Song, M., Wang, Y., Wang, W. (2016). Glycan Biomarkers for Rheumatoid Arthritis and Its Remission Status in Han Chinese Patients. OMICS A Journal of Integrative Biology, 20(6), 343-351. https://doi.org/10.1089/omi.2016.0050.
  • Wang, Y., Ge, S., Yan, Y., Wang, A., Zhao, Z., Yu, X., Qiu, J., Alzain, M., Wang, H., Fang, H., Gao, Q., Song, M., Zhang, J., Zhou, Y., Wang, W. (2016). China suboptimal health cohort study: rationale, design and baseline characteristics. Journal of Translational Medicine, 14(1), article no.291. https://doi.org/10.1186/s12967-016-1046-y.
  • Rao, P., Wang, H., Gao, Q., Zhang, J., Song, M., Zhou, Y., Wang, Y., Wang, W. (2016). Association between IGF2BP2 Polymorphisms and Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis. International Journal of Environmental Research and Public Health, 13(6), Article no. 574. https://doi.org/10.3390/ijerph13060574.
  • Rao, P., Zhou, Y., Ge, S., Wang, A., Yu, X., Alzain, M., Veronica, A., Qiu, J., Song, M., Zhang, J., Wang, H., Fang, H., Gao, Q., Wang, Y., Wang, W. (2016). Validation of Type 2 Diabetes Risk Variants Identified by Genome‐Wide Association Studies in Northern Han Chinese. International Journal of Environmental Research and Public Health, 13(9), Article no.863. https://doi.org/10.3390/ijerph13090863.
  • Sebastian, A., Alzain, M., Asweto, C., Mahara, G., Guo, X., Song, M., Wang, Y., Wang, W. (2016). The Malaysian health care system: Ecology, plans, and reforms. Family Medicine and Community Health, 4(3), 19-29. https://doi.org/10.15212/FMCH.2016.0101.
  • Zhao, F., Mamatyusupu, D., Wang, Y., Fang, H., Wang, H., Gao, Q., Dong, H., Ge, S., Yu, X., Zhang, J., Wu, L., Song, M., Wang, W. (2016). The Uyghur population and genetic susceptibility to type 2 diabetes: potential role for variants in CAPN10, APM1 and FUT6genes. Journal of Cellular and Molecular Medicine, 20(11), 2138-2147. https://doi.org/10.1111/jcmm.12911.

2015

Journal Articles

  • Yan, Y., Dong, J., Liu, Y., Zhang, J., Song, M., He, Y., Wang, W. (2015). Association of suboptimal health status with psychosocial stress, plasma cortisol and mRNA expression of glucocorticoid receptor a/b in lymphocyte. Stress, 18(1), 29-34. https://doi.org/10.3109/10253890.2014.999233.
  • Song, M., Zhao, F., Ran, L., Dolikun, M., Wu, L., Ge, S., Dong, H., Gao, Q., Zhai, Y., Zhang, L., Yan, Y., Liu, F., Yang, X., Guo, X., Wang, Y., Wang, W. (2015). The Uyghur population and genetic susceptibility to type 2 diabetes: Potential role for variants in CDKAL1, JAZF1, and IGF1 genes. OMICS: A Journal of Integrative Biology, 19(4), 230-237. https://doi.org/10.1089/omi.2014.0162.

2014

Journal Articles

  • Zhao, F., Chen, Y., Ge, S., Yu, X., Shao, S., Black, M., Wang, Y., Zhang, J., Song, M., Wang, W. (2014). A Quantitative Analysis of the Mass Media Coverage of Genomics Medicine in China: A Call for Science Journalism in the Developing World. OMICS: A Journal of Integrative Biology, 18(4), 222-230. https://doi.org/10.1089/omi.2013.0108.
  • Li, J., Lou, H., Yang, X., Lu, D., Li, S., Jin, L., Pan, X., Yang, W., Song, M., Mamatyusupu, D., Xu, S. (2014). Genetic architectures of ADME genes in five Eurasian admixed populations and implications for drug safety and efficacy. Journal of Medical Genetics, 51(9), 614-622. https://doi.org/10.1136/jmedgenet-2014-102530.
  • Wu, L., Wang, Y., Xiaoxia, P., Song, M., Guo, X., Nelson, H., Wang, W. (2014). Development of a medical academic degree system in China. Medical Education Online: an electronic journal, 19(1), Article 23141. https://doi.org/10.3402/meo.v19.23141.

2013

Journal Articles

  • Wu, J., Zhang, L., Zhang, J., Dai, Y., Bian, L., Song, M., Russell, A., Wang, W. (2013). The genetic contribution of CIDEA polymorphisms, haplotypes and loci interaction to obesity in a Han Chinese population. Molecular Biology Reports: an international journal on molecular and cellular biology, 40(10), 5691-5699. https://doi.org/10.1007/s11033-013-2671-7.
  • Wang, Y., Wu, L., Yu, X., Zhao, F., Russell, A., Song, M., Wang, W. (2013). The Expected Number of Background Disease Events during Mass Immunization in China. PLoS One, 8(8), e71818. https://doi.org/10.1371/journal.pone.0071818.

2012

Book Chapters

  • Song, M., Wang, Y., Wu, L., Wang, Y., Wang, W. (2012). Community and Public Health Genetics in China. Genomics and Health in the Developing World (829-835). Oxford University Press.
  • Yun, H., Song, M., Wang, W. (2012). Traditional Chinese Medicine in the Area of Genomics. Genomics and Health in the Developing World (842-845). Oxford University Press.

Journal Articles

  • Wang, C., Wang, YX., Huang, XJ., Li, X., Zhang, T., Song, M., Wu, LJ., Du, J., Lu, XQ., Shao, S., Zhao, FF., Ball, M., Wu, H., Wang, W. (2012). Prevalence and Factors Associated with Hepatitis B Immunization and Infection among Men Who Have Sex with Men in Beijing, China. PLoS One, 7(10), art. no. e48219. https://doi.org/10.1371/journal.pone.0048219.
  • Yun, H., Hou, L., Song, M., Wang, Y., Zakus, D., Wu, L., Wang, W. (2012). Genomics and Traditional Chinese Medicine: A New Driver for Novel Molecular-Targeted Personalized Medicine?. Current Pharmacogenomics and Personalized Medicine, 10(1), 16-21.
  • Lu, J., Sheng, A., Wang, Y., Zhang, L., Wu, J., Song, M., He, Y., Yu, X., Zhao, F., Liu, Y., Shao, S., Lan, J., Wu, H., Wang, W. (2012). The Genetic Associations and Epistatic Effects of the CCR5 Promoter and CCR2-V64I Polymorphisms on Susceptibility to HIV-1 Infection in a Northern Han Chinese Population. Genetic Testing and Molecular Biomarkers, 16(12), 1369-1375. https://doi.org/10.1089/gtmb.2012.0235.
  • Meng, C., Lan, J., Wang, Y., Song, M., Gao, X., Ran, L., Sim, M., Wang, W. (2012). Influence of brain-derived neurotrophic factor genetic polymorphisms on the ages of onset for heroin dependence in a Chinese population.. Genetic Testing and Molecular Biomarkers, 16(9), 1044-1050. https://doi.org/10.1089/gtmb.2012.0016.
  • Lu, J., Huang, Y., Wang, Y., Li, Y., Zhang, Y., Wu, J., Zhao, F., Meng, S., Yu, X., Ma, Q., Song, M., Chang, N., Bittles, A., Wang, W. (2012). Profiling Plasma Peptides for the Identification of Potential Ageing Biomarkers in Chinese Han Adults. PLoS One, 7(7), e39726. https://doi.org/10.1371/journal.pone.0039726.

2011

Journal Articles

  • Ma, W., Du, J., Chu, Q., Wang, Y., Liu, L., Song, M., Wang, W. (2011). hCLP46 regulates U937 cell proliferation via Notch signaling pathway. Biochemical and Biophysical Research Communications, 408(1), 84-88. https://doi.org/10.1016/j.bbrc.2011.03.124.
  • Lu, J., Knezevic, A., Wang, Y., Rudan, I., Campbell, H., Zou, Z., Lan, J., Lai, Q., Wu, J., He, Y., Song, M., Zhang, L., Lauc, G., Wang, W. (2011). Screening Novel Biomarkers for Metabolic Syndrome by Profiling Human Plasma N-Glycans in Chinese Han and Croatian Populations. Journal of Proteome Research, 10(11), 4959-4969. https://doi.org/10.1021/pr2004067.
  • Zhou, Z., Hu, H., Song, M., Shen, Y., Guo, X., McElreavey, K., Bittles, A., Wang, W. (2011). Semen quality analysis of military personnel from six geographical areas of the People’s Republic of China. Fertility and Sterility, 95(6), 2018-2023. https://doi.org/10.1016/j.fertnstert.2011.02.052.

2010

Journal Articles

  • Zhang, J., Zhang, L., Song, M., Wang, W. (2010). Detection of HBV-DNA in Dried Bloodstains on Filter Paper by Nested Polymerase Chain Reaction. Laboratory medicine, 41(9), 537-539. https://doi.org/10.1309/LMGVUU8ETVJNX91Y.
  • Sheng, A., Lan, J., Wu, H., Lu, J., Wang, Y., Chu, Q., Jia, Z., Song, M., Liu, L., Wang, W. (2010). A clinical case–control study on the association between mannose-bindinglectin and susceptibility to HIV-1 infection among northern Han Chinese population. International Journal of Immunogenetics, 37(6), 445-454. https://doi.org/10.1111/j.1744-313X.2010.0094.
  • Zheng, S., Song, M., Wu, L., Yang, S., Shen, J., Lu, X., Du, J., Wang, W. (2010). China: Public Health Genomics. Public Health Genomics, 13(5), 269-275. https://doi.org/10.1159/000240969.

Research Projects

  • Exploring and translating subjective and objective measures of suboptimal cardiometabolic health in a community-orientated setting , Department of Health WA, WA Near-miss Awards: Ideas, 2024 ‑ 2025, $100,000.
  • Towards personalised medicine via population-based study of variability of the human IgG glycome, Seigo Co., ltd, Grant, 2020 ‑ 2022, $300,000.

Research Student Supervision

Current Supervisions

Associate Supervisor

  • Doctor of Philosophy, From Sugar Code to Precision Medicine: Expanding Cellular Information Beyond the Central Dogma
  • Doctor of Philosophy, Development of a Nanobody-based Tri-specific T Cell Engager for Enhanced Immunotherapy in Colorectal Cancer
  • Doctor of Philosophy, Investigating the Therapeutic Potential of a Bispecific Antibody Targeting PD-1 and MSLN in Colon Cancer.
  • Doctor of Philosophy, Data mining for dementia prevention using mobile phone applications (the PRODEMOS study) in China: A multicentre randomised controlled effectiveness-implementation trial

Completed Supervisions

Co-principal Supervisor

  • Doctor of Philosophy, Horizontal QRS Axis Predicts Cardiac Resynchronization Therapy Response and Prognosis in Heart Failure Patients with Prolonged QRS Duration

Associate Supervisor

  • Master of Science (Human Biology), Impact of biobanks on research outcomes in rare diseases: A systematic review
  • Doctor of Philosophy, Clinical Implications of Bovine Arch in Thoracic Endovascular Aortic Repair for Type B Aortic Dissection
  • Doctor of Philosophy, Development and Validation of IgG N-Glycosylation-Based Nomograms for Early Diagnosis and Postoperative Recurrence Risk Prediction of Colorectal Cancer in Chinese Han Population
  • Doctor of Philosophy, Investigating the Role of IgG N-Glycosylation in Diagnosis, Disease Activity, and Causal Inference of Sjogren disease
  • Doctor of Philosophy, Investigating the Role of IgG N-glycosylation in Diagnosis and Disease Activity of Axial Spondyloarthritis
  • Doctor of Philosophy, Developing a novel diagnostic model for accurate differentiation between left and right outflow tract ventricular arrhythmias
  • Doctor of Philosophy, Heritability enrichment of immunoglobulin G N-Glycosylation-relevant genes in specific tissues

Adjunct Supervisor

  • Doctor of Philosophy, Inflammation, metabolic disorders and incident type 2 diabetes

External University

  • Doctor of Philosophy, The roles of IgG N-glycome in insulin resistance
  • Doctor of Philosophy, Investigating the expression and role of circular RNAs in the pathogenesis of osteosarcoma
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