ECU offers innovative and practical courses across a variety of disciplines and we have a vibrant research culture. ECU is a leader in developing alternative entry pathways to higher education.
We have three campuses in Western Australia. Joondalup and Mount Lawley in the Perth metropolitan area and our South West campus in Bunbury, 200km south of the Perth CBD.
ECU provides a variety of services and facilities that go beyond the classroom, with opportunities for personal development and social interaction for students and staff.
We collaborate with all types of businesses, including new start-ups, small to medium enterprises, not-for-profits, community organisations, government and large corporates in the resources sector.
Children's University Edith Cowan aims to inspire students between seven and fourteen to develop confidence and a love of learning through validated activities beyond the school curriculum.
The Inspiring Minds scholarship program are equity scholarships that give students an opportunity to access an education that may otherwise be out of reach.
Chatterjee, P., Pedrini, S., Stoops, E., Goozee, K., Villemagne, V., Asih, P., Verberk, I., Dave, P., Taddei, K., Sohrabi, H., Zetterberg, H., Blennow, K., Teunissen, C., Vanderstichele, H., Martins, R. (2021). Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer’s disease. Translational Psychiatry, 11(2021), Article 27. https://doi.org/10.1038/s41398-020-01137-1.
Chatterjee, P., Cheong, Y., Bhatnagar, A., Goozee, K., Wu, Y., McKay, M., Martins, I., Lim, F., Pedrini, S., Tegg, M., Villemagne, V., Asih, P., Dave, P., Shah, T., Dias, C., Fuller, S., Hillebrandt, H., Gupta, S., Hone, E., Taddei, K., Zetterberg, H., Blennow, K., Sohrabi, H., Martins, R. (2020). Plasma metabolites associated with biomarker evidence of neurodegeneration in cognitively normal older adults. Journal of Neurochemistry, 2020(Article in press), 14p.. https://doi.org/10.1111/jnc.15128.
Chatterjee, P., Mohammadi, M., Goozee, K., Shah, T., Sohrabi, H., Dias, C., Shen, K., Asih, P., Dave, P., Pedrini, S., Ashton, N., Hye, A., Taddei, K., Lovejoy, D., Zetterberg, H., Blennow, K., Martins, R. (2020). Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load. Journal of Alzheimer's Disease, 76(2020), 291-301. https://doi.org/10.3233/JAD-200162.
Sohrabi, H., Goozee, K., Weinborn, M., Shen, K., Brown, B., Rainey-Smith, S., Salvado, O., Taddei, K., Bucks, R., Maruff, P., Laws, S., Lenzo, N., Laws, M., Deyoung, C., Speelman, C., Laske, C., Ames, D., Savage, G., Martins, R. (2020). Personality factors and cerebral glucose metabolism in community‑dwelling older adults. Brain Structure and Function, 225(5), 1511–1522. https://doi.org/10.1007/s00429-020-02071-0.
Pedrini, S., Hone, E., Gupta, V., James, I., Teimouri, E., Bush, A., Rowe, C., Villemagne, V., Ames, D., Masters, C., Rainey-Smith, S., Verdile, G., Sohrabi, H., Raida, M., Wenk, M., Taddei, K., Chatterjee, P., Martins, I., Laws, S., Martins, R. (2020). Plasma High Density Lipoprotein Small Subclass is Reduced in Alzheimer’s Disease Patients and Correlates with Cognitive Performance. Journal of Alzheimer's Disease, 77(2), 733-744. https://doi.org/10.3233/JAD-200291.
Jayakody, D., Menegola, H., Yiannos, J., Goodman-Simpson, J., Friedland, P., Taddei, K., Laws, S., Weinborn, M., Martins, R., Sohrabi, H. (2020). The peripheral hearing and Central Auditory Processing skills of individuals with subjective memory complaints. Frontiers in Neuroscience, 14(21 August 2020), Article 888. https://doi.org/10.3389/fnins.2020.00888.
Schultz, A., Kloet, R., Sohrabi, H., Van Der Weerd, L., Van Rooden, S., Wermer, M., Moursel, L., Yaqub, M., Van Berckel, B., Chatterjee, P., Kirby, S., Taddei, K., Fagan, A., Benzinger, T., Morris, J., Sperling, R., Johnson, K., Bateman, R., Gurol, ME., Van Buchem, M., Martins, R., Chhatwal, J., Greenberg, S. (2019). Amyloid Imaging of Dutch-Type Hereditary Cerebral Amyloid Angiopathy Carriers. Annals of Neurology, 86(4), 616-625. https://doi.org/10.1002/ana.25560.
Tan, S., Sohrabi, H., Weinborn, M., Tegg, M., Bucks, R., Taddei, K., Carruthers, M., Martins, R. (2019). Effects of Testosterone Supplementation on Separate Cognitive Domains in Cognitively Healthy Older Men: A Meta-analysis of Current Randomized Clinical Trials. American Journal of Geriatric Psychiatry, 27(11), 1232-1246. https://doi.org/10.1016/j.jagp.2019.05.008.
Hata, S., Omori, C., Kimura, A., Saito, H., Kimura, N., Gupta, V., Pedrini, S., Hone, E., Chatterjee, P., Taddei, K., Kasuga, K., Ikeuchi, T., Waragai, M., Nishimura, M., Hu, A., Nakaya, T., Meijer, L., Maeda, M., Yamamoto, T., Masters, C., Rowe, C., Ames, D., Yamamoto, K., Martins, R., Gandy, S., Suzuki, T. (2019). Decrease in p3-Alcb37 and p3-Alcb40, products of Alcadein b generated by g-secretase cleavages, in aged monkeys and patients with Alzheimer’s disease. Alzheimer's & Dementia: Translational Research & Clinical Interventions, 5(2019), 740-750. https://doi.org/https://doi.org/10.1016/j.trci.2019.09.015.
Chatterjee, P., Zetterberg, H., Goozee, K., Lim, C., Jacobs, K., Ashton, N., Hye, A., Pedrini, S., Sohrabi, H., Shah, T., Asih, P., Dave, P., Shen, K., Taddei, K., Lovejoy, D., Guillemin, G., Blennow, K., Martins, R. (2019). Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease. Journal of Neuroinflammation, 16(2019), Article number 186. https://doi.org/10.1186/s12974-019-1567-4.
Dube, U., Del-Aguila, J., Li, Z., Budde, J., Jiang, S., Hsu, S., Ibanez, L., Fernandez, M., Farias, F., Norton, J., Gentsch, J., Wang, F., Allegri, R., Amtashar, F., Benzinger, T., Berman, S., Bodge, C., Brandon, S., Brooks, W., Buck, J., Buckles, V., Chea, S., Chrem, P., Chui, H., Cinco, J., Clifford, J., D’mello, M., Donahue, T., Douglas, J., Edigo, N., Erekin-Taner, N., Fagan, A., Farlow, M., Farrar, A., Feldman, H., Flynn, G., Fox, N., Franklin, E., Fujii, H., Gant, C., Kirby, S., Ghetti, B., Goate, A., Goldman, J., Gordon, B., Gray, J., Gurney, J., Hassenstab, J., Hirohara, M., Holtzman, D., Hornbeck, R., Dibari, S., Ikeuchi, T., Ikonomovic, S., Jerome, G., Jucker, M., Kasuga, K., Kawarabayashi, T., Klunk, W., Koeppe, R., Kuder-Buletta, E., Laske, C., Levin, J., Marcus, D., Martins, R., Mason, N., Maue-Dreyfus, D., McDade, E., Montoya, L., Mori, H., Nagamatsu, A., Neimeyer, K., Noble, J., Perrin, R., Raichle, M., Ringman, J., Roh, J., Schofield, P., Shimada, H., Shiroto, T., Shoji, M., Sigurdson, W., Sohrabi, H., Sparks, P., Suzuki, K., Swisher, L., Taddei, K., Wang, J., Wang, P., Weiner, M., Wolfsberger, M., Xiong, C., Xu, X., Salloway, S., Masters, C., Lee, J., Graff-Radford, N., Chhatwal, J., Bateman, R., Morris, J., Karch, C., Harari, O., Cruchaga, C. (2019). An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. Nature Neuroscience, 22(11), 1903-1912. https://doi.org/10.1038/s41593-019-0501-5.
Chatterjee, P., Elmi, M., Goozee, K., Shah, T., Sohrabi, H., Dias, C., Pedrini, S., Shen, K., Asih, P., Dave, P., Taddei, K., Vanderstichele, H., Zetterberg, H., Blennow, K., Martins, R. (2019). Ultrasensitive Detection of Plasma Amyloid-β as a Biomarker for Cognitively Normal Elderly Individuals at Risk of Alzheimer's Disease. Journal of Alzheimer's Disease, 71(3), 775-783. https://doi.org/10.3233/JAD-190533.
Sohrabi, H., Weinborn, M., Laske, C., Bates, K., Christensen, D., Taddei, K., Rainey-Smith, S., Brown, B., Kirby, S., Laws, S., Martins, G., Burnham, S., Bucks, R., Reisberg, B., Lautenschlager, N., Foster, J., Martins, R. (2019). Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study. International Psychogeriatrics, 31(4), 513-525. https://doi.org/10.1017/S1041610218001072.
Rainey-Smith, S., Mazzucchelli, G., Villemagne, V., Brown, B., Porter, T., Weinborn, M., Bucks, R., Milicic, L., Sohrabi, H., Taddei, K., Ames, D., Maruff, P., Masters, C., Rowe, C., Salvado, O., Martins, R., Laws, S. (2018). Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden. Translational Psychiatry, 8(1), Article no. 47. https://doi.org/10.1038/s41398-018-0094-x.
Weinborn, M., Bucks, R., Sohrabi, H., Rainey-Smith, S., Brown, B., Kirby, S., Gozt, O., Christensen, D., Savage, G., Laws, S., Taddei, K., Maruff, P., Robertson, J., Ellis, K., Ames, D., Masters, C., Rowe, C., Martins, R. (2018). Trajectories of Irregular Word Reading Ability as a Proxy for Premorbid Intelligence in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Aging: A Longitudinal Study. Psychological Assessment, 30(10), 1308-1316. https://doi.org/10.1037/pas0000565.
Porter, T., Villemagne, V., Savage, G., Milicic, L., Lim, YY., Maruff, P., Masters, C., Ames, D., Bush, A., Martins, R., Rainey-Smith, S., Rowe, C., Taddei, K., Groth, D., Verdile, G., Burnham, S., Laws, S. (2018). Cognitive gene risk profile for the prediction of cognitive decline in presymptomatic Alzheimer’s disease. Personalized Medicine in Psychiatry, 7-8(2018), 14-20. https://doi.org/10.1016/j.pmip.2018.03.001.
Brown, B., Rainey-Smith, S., Dore, V., Peiffer, J., Burnham, S., Laws, S., Taddei, K., Ames, D., Masters, C., Rowe, C., Martins, R., Villemagne, V. (2018). Self-Reported Physical Activity is Associated with Tau Burden Measured by Positron Emission Tomography. Journal of Alzheimer's Disease, 63(4), 1299-1305. https://doi.org/10.3233/JAD-170998.
Rainey-Smith, S., Gu, Y., Kirby, S., Doecke, J., Villemagne, V., Brown, B., Taddei, K., Laws, S., Sohrabi, H., Weinborn, M., Ames, D., Fowler, C., Macaulay, SL., Maruff, P., Masters, C., Salvado, O., Rowe, C., Scarmeas, N., Martins, R. (2018). Mediterranean diet adherence and rate of cerebral Aβ-amyloid accumulation: Data from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Translational Psychiatry, 8(1), 238-244. https://doi.org/10.1038/s41398-018-0293-5.
Porter, T., Burnham, S., Savage, G., Lim, YY., Maruff, P., Milicic, L., Peretti, M., Ames, D., Masters, C., Martins, R., Rainey-Smith, S., Rowe, C., Salvado, O., Taddei, K., Groth, D., Verdile, G., Villemagne, V., Laws, S. (2018). A polygenic risk score derived from episodic memory weighted genetic variants is associated with cognitive decline in preclinical Alzheimer's disease. Frontiers in Aging Neuroscience, 10(Dec 2018), Article number 423. https://doi.org/10.3389/fnagi.2018.00423.
Goozee, K., Chatterjee, P., James, I., Shen, K., Sohrabi, H., Asih, P., Dave, P., Manyan, C., Taddei, K., Ayton, S., Garg, M., Kwok, J., Bush, A., Chung, R., Magnussen, J., Martins, R. (2018). Elevated plasma ferritin in elderly individuals with high neocortical amyloid-β load. Molecular Psychiatry, 23(8), 1807-1812. https://doi.org/10.1038/mp.2017.146.
Fernando, B., Rainey-Smith, S., Kirby, S., Villemagne, V., Burnham, S., Macaulay, SL., Brown, B., Gupta, V., Sohrabi, H., Weinborn, M., Taddei, K., Laws, S., Goozee, K., Ames, D., Fowler, C., Maruff, P., Masters, C., Salvado, O., Rowe, C., Martins, R. (2018). Associations of dietary protein and fiber intake with brain and blood amyloid-β. Journal of Alzheimer's Disease, 61(4), 1589-1598. https://doi.org/10.3233/JAD-170742.
Doecke, J., Rembach, A., Villemagne, V., Varghesi, S., Rainey-Smith, S., Sarros, S., Evered, L., Fowler, C., Pertile, K., Rumble, R., Trounson, B., Taddei, K., Laws, S., Macaulay, SL., Bush, A., Ellis, K., Martins, R., Ames, D., Silbert, B., Vanderstichele, H., Masters, C., Darby, D., Li, Q., Collins, S. (2018). Concordance between cerebrospinal fluid biomarkers with Alzheimer's disease pathology between three independent assay platforms. Journal of Alzheimer's Disease, 61(1), 169-183. https://doi.org/10.3233/JAD-170128.
McCabe, K., Woods, S., Weinborn, M., Sohrabi, H., Rainey-Smith, S., Brown, B., Kirby, S., Taddei, K., Martins, R. (2018). Personality characteristics are independently associated with prospective memory in the laboratory, and in daily Life, among older adults. Journal of Research in Personality, 76(Oct 2018), 32-37. https://doi.org/10.1016/j.jrp.2018.06.006.
Chatterjee, P., Goozee, K., Sohrabi, H., Shen, K., Shah, T., Asih, P., Dave, P., Man Yan, C., Taddei, K., Chung, R., Zetterberg, H., Blennow, K., Martins, R. (2018). Association of Plasma Neurofilament Light Chain with Neocortical Amyloid-β Load and Cognitive Performance in Cognitively Normal Elderly Participants. Journal of Alzheimer's Disease, 63(2), 479-487. https://doi.org/10.3233/JAD-180025.
Chatterjee, P., Goozee, K., Lim, CK., James, I., Shen, K., Jacobs, K., Sohrabi, H., Shah, T., Asih, P., Dave, P., Manyan, C., Taddei, K., Lovejoy, D., Chung, R., Guillemin, G., Martins, R. (2018). Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-B load: A pilot study. Scientific Reports, 8(2018), Article no. 8008. https://doi.org/10.1038/s41598-018-25968-7.
Martins, R., Villemagne, V., Sohrabi, H., Chatterjee, P., Shah, T., Verdile, G., Fraser, P., Taddei, K., Gupta, V., Rainey-Smith, S., Hone, E., Pedrini, S., Lim, F., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K., Fuller, S., Brown, B., Kirby, S., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S., Barron, A., Goozee, K., Wahjoepramono, EJ., Asih, P., Doecke, J., Salvado, O., Bush, A., Rowe, C., Gandy, S., Masters, C. (2018). Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease, 62(3), 965-992. https://doi.org/10.3233/JAD-171145.
Peters, K., Davis, W., Taddei, K., Martins, R., Masters, C., Davis, T., Bruce, D. (2017). Plasma amyloid-β Peptides in Type 2 Diabetes: A matched case-control study. Journal of Alzheimer's Disease, 56(3), 1127-1133. https://doi.org/10.3233/JAD-161050.
Goozee, K., Chatterjee, P., James, I., Shen, K., Sohrabi, H., Asih, P., Dave, P., Ball, B., Manyan, C., Taddei, K., Chung, R., Garg, M., Martins, R. (2017). Alterations in erythrocyte fatty acid composition in preclinical Alzheimer’s disease. Scientific Reports, 7(1), Article number 676. https://doi.org/10.1038/s41598-017-00751-2.
Kirby, S., Rainey-Smith, S., Sohrabi, H., Weinborn, M., Verdile, G., Fernando, B., Lim, YY., Harrington, K., Burnham, S., Taddei, K., Masters, C., Macaulay, S., Rowe, C., Ames, D., Maruff, P., Martins, R. (2017). Increased carbohydrate intake is associated with poorer performance in verbal memory and attention in an APOE genotype-dependent manner. Journal of Alzheimer's Disease, 58(1), 193-201. https://doi.org/10.3233/JAD-161158.
Frost, S., Robinson, L., Rowe, C., Ames, D., Masters, C., Taddei, K., Rainey-Smith, S., Martins, R., Kanagasingam, Y. (2017). Evaluation of cholinergic deficiency in preclinical Alzheimer's disease using pupillometry. Journal of Ophthalmology, 2017(August 2017), Article no. 7935406. https://doi.org/10.1155/2017/7935406.
Brown, B., Sohrabi, H., Taddei, K., Kirby, S., Rainey-Smith, S., Peiffer, J., Xiong, C., Fagan, A., Benzinger, T., Buckles, V., Erickson, K., Clarnette, R., Shah, T., Masters, C., Weiner, M., Cairns, N., Rossor, M., Graff-Radford, N., Salloway, S., Voglein, J., Laske, C., Noble, J., Schofield, P., Bateman, R., Morris, J., Martins, R. (2017). Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer’s disease. Alzheimer's and Dementia, 13(11), 1197-1206. https://doi.org/10.1016/j.jalz.2017.03.008.
Bates, K., Sohrabi, H., Rainey-Smith, S., Weinborn, M., Bucks, R., Rodrigues, M., Beilby, J., Howard, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, L., Gandy, S., Martins, R. (2017). Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women. International Journal of Neuroscience, 127(3), 243-252. https://doi.org/10.1080/00207454.2016.1182527.
Kirby, S., Sohrabi, H., Shen, K., Rainey-Smith, S., Weinborn, M., Bates, K., Shah, T., Foster, J., Lenzo, N., Salvado, O., Laske, C., Laws, S., Taddei, K., Verdile, G., Martins, R. (2016). Cerebral Glucose Metabolism is Associated with Verbal but not Visual Memory Performance in Community-Dwelling Older Adults. Journal of Alzheimer's Disease, 52(2), 661-672. https://doi.org/10.3233/JAD-151084.
Chatterjee, P., Lim, F., Shui, G., Gupta, V., James, I., Fagan, A., Xiong, C., Sohrabi, H., Taddei, K., Brown, B., Benzinger, T., Masters, C., Snowden, S., Wenk, M., Bateman, R., Morris, J., Martins, R. (2016). Plasma Phospholipid and Sphingolipid Alterations in Presnilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's disease, 50(3), 887-894. https://doi.org/10.3233/JAD-150948.
Bird, S., Sohrabi, H., Sutton, T., Weinborn, M., Rainey-Smith, S., Brown, B., Patterson, L., Taddei, K., Gupta, V., Carruthers, M., Lenzo, N., Knuckey, N., Bucks, R., Verdile, G., Martins, R. (2016). Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies. Neuroscience & Biobehavioural Reviews, 64(2016), 215-228. https://doi.org/10.1016/j.neubiorev.2016.01.004.
Brown, B., Rainey-Smith, S., Villemagne, V., Weinborn, M., Bucks, R., Sohrabi, H., Laws, S., Taddei, K., Macaulay, SL., Ames, D., Fowler, C., Maruff, P., Masters, C., Rowe, C., Martins, R. (2016). The relationship between sleep quality and brain amyloid burden. Sleep, 39(5), 1063-1068. https://doi.org/10.5665/sleep.5756.
Barr, R., Verdile, G., Wijaya, L., Morici, M., Taddei, K., Gupta, V., Pedrini, S., Jin, L., Nicolazzo, JA., Knock, E., Fraser, P., Martins, R. (2016). Validation and characterization of a novel peptide that binds monomeric and aggregated β-Amyloid and inhibits the formation of neurotoxic oligomers. Journal of Biological Chemistry, 291(2), 547-559. https://doi.org/10.1074/jbc.M115.679993.
Wahjoepramono, EJ., Asih, P., Aniwiyanti, V., Taddei, K., Dhaliwal, S., Fuller, S., Foster, J., Carruthers, M., Verdile, G., Sohrabi, H., Martins, R. (2016). The effects of testosterone supplementation on cognitive functioning in older men. CNS and Neurological Disorders, 15(3), 337-343. https://doi.org/10.2174/1871527315666151110125704.
Chatterjee, P., Gupta, V., Fagan, A., Jasielec, M., Xiong, C., Sohrabi, H., Dhaliwal, S., Taddei, K., Bourgeat, P., Brown, B., Benzinger, T., Bateman, R., Morris, J., Martins, R. (2015). Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer's Disease: Baseline Data from a DIAN Cohort Subset. Current Alzheimer Research, 12(2), 157-164. https://doi.org/10.2174/1567205012666150204125732.
Kirby, S., Rainey-Smith, S., Macaulay, SL., Taddei, K., Rembach, A., Maruff, P., Ellis, K., Masters, C., Rowe, C., Ames, D., Keogh, J., Martins, R. (2015). Comparative analysis of the Cancer Council of Victoria and the online Commonwealth Scientific and Industrial Research Organisation FFQ. The British Journal of Nutrition: an international journal of nutritional science, 114(10), 1683-1693. https://doi.org/10.1017/S0007114515003335.
Johnson, L., Sohrabi, H., Hall, J., Taddei, K., Edwards, M., O'Bryant, S., Martins, R. (2015). A depressive endophenotype of poorer cognition among cognitively healthy community-dwelling adults: results from the Western Australia memory study. International Journal of Geriatric Psychiatry, 30(8), 881-886. https://doi.org/10.1002/gps.4231.
Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R. (2015). Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16. https://doi.org/10.3389/fnagi.2015.00016.
Li, Q., Villemagne, V., Doecke, J., Rembach, A., Sarros, S., Varghese, S., McGlade, A., Laughton, K., Pertile, K., Fowler, C., Rumble, R., Trounson, B., Taddei, K., Rainey-Smith, S., Laws, S., Robertson, J., Evered, L., Silbert, B., Ellis, K., Rowe, C., Macaulay, S., Darby, D., Martins, R., Ames, D., Masters, C., Collins, S. (2015). Alzheimer’s Disease Normative Cerebrospinal Fluid Biomarkers Validated in PET Amyloid-β Characterized Subjects from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study. Journal of Alzheimer's Disease, 48(1), 175-187. https://doi.org/10.3233/JAD-150247.
Rembach, A., Evered, L., Li, Q., Nash, T., Vidaurre, L., Fowler, CJ., Pertile, KK., Rumble, RL., Trounson, BO., Maher, S., Mooney, F., Farrow, M., Taddei, K., Rainey-Smith, S., Laws, S., Macaulay, SL., Wilson, W., Darby, DG., Martins, R., Ames, D., Collins, S., Silbert, B., Masters, CL., Doecke, JD. (2015). Alzheimer's Disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology. Alzheimer's Research and Therapy, 7(2015), Article number 71. https://doi.org/10.1186/s13195-015-0157-7.
Kirby, S., Rainey-Smith, S., Barnes, M., Sohrabi, H., Weinborn, M., Lim, Y., Harrington, K., Taddei, K., Gu, Y., Rembach, A., Szoeke, C., Ellis, K., Masters, C., Macaulay, S., Rowe, C., Ames, D., Keogh, J., Scarmeas, N., Martins, R. (2015). Dietary patterns and cognitive decline in an Australian study of ageing. Molecular Psychiatry, 20(7), 860-866. https://doi.org/10.1038/mp.2014.79.
Asih, P., Wahjoepramono, EJ., Aniwiyanti, V., Wijaya, L., De Ruyck, K., Taddei, K., Fuller, SJ., Sohrabi, H., Dhaliwal, SS., Verdile, G., Carruthers, M., Martins, R. (2015). Testosterone Replacement Therapy in Older Male Subjective Memory Complainers: Double-Blind Randomized Crossover Placebo-Controlled Clinical Trial of Physiological Assessment and Safety. CNS and Neurological Disorders, 14(5), 576-586.
Cysique, LA., Hewitt, T., Croitoru-Lamoury, J., Taddei, K., Martins, R., Chew, CS., Davies, NN., Price, P., Brew, BJ. (2015). APOE e4 moderates abnormal CSF-abeta-42 levels, while neurocognitive impairment is associated with abnormal CSF tau levels in HIV+ individuals - A cross-sectional observational study. BMC Neurology, 15(1), Article no. 51. https://doi.org/10.1186/s12883-015-0298-0.
Albrecht, MA., Szoeke, C., Maruff, P., Savage, G., Lautenschlager, NT., Ellis, KA., Taddei, K., Martins, R., Masters, CL., Ames, D., Foster, JK. (2015). Longitudinal cognitive decline in the AIBL cohort: The role of APOE e4 status. Neuropsychologia, 75(2015), 411-419. https://doi.org/10.1016/j.neuropsychologia.2015.06.008.
Villemagne, V., Dore, V., Yates, P., Brown, B., Mulligan, R., Bourgeat, P., Veljanoski, R., Rainey-Smith, S., Ong, K., Rembach, A., Williams, R., Burnham, S., Laws, S., Salvado, O., Taddei, K., Macaulay, SL., Martins, R., Ames, D., Masters, C., Rowe, C. (2014). En Attendant Centiloid. Advances in Research, 2(12), 723-729. https://doi.org/10.9734/AIR/2014/11599.
Rembach, A., Faux, N., Watt, A., Pertile, K., Rumble, R., Trounson, B., Fowler, C., Roberts, B., Perez, K., Li, Q., Laws, S., Taddei, K., Rainey-Smith, S., Robertson, J., Vandijck, M., Vanderstichele, H., Barnham, K., Ellis, K., Szoeke, C., Macaulay, L., Rowe, C., Villemagne, V., Ames, D., Martins, R., Bush, A., Masters, C. (2014). Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimer's and Dementia, 10(1), 53-61. https://doi.org/10.1016/j.jalz.2012.12.006.
Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoeke, C., Taddei, K., Villemagne, V., Martins, R. (2014). Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry, 19(1), 69-75. https://doi.org/10.1038/mp.2012.147.
Brown, B., Bourgeat, P., Peiffer, J., Burnham, S., Laws, S., Rainey-Smith, S., Bartres-Faz, D., Villemagne, V., Taddei, K., Rembach, A., Bush, A., Ellis, K., Macaulay, SL., Rowe, C., Ames, D., Masters, C., Maruff, P., Martins, R. (2014). Influence of BDNF Val66Met on the relationship between physical activity and brain volume. Neurology, 83(15), 1345-52. https://doi.org/10.1212/WNL.0000000000000867.
Frost, S., Kanagasingam, Y., Sohrabi, H., Taddei, K., Bateman, R., Morris, J., Benzinger, T., Goate, A., Masters, C., Martins, R. (2013). Pupil Response Biomarkers Distinguish Amyloid Precursor Protein Mutation Carriers from Non-Carriers. Current Alzheimer Research, 10(8), 790-796. https://doi.org/10.2174/15672050113109990154.
Foster, J., Albrecht, M., Savage, G., Lautenschlager, N., Ellis, K., Maruff, P., Szoeke, C., Taddei, K., Martins, R., Masters, C., Ames, D. (2013). Lack of reliable evidence for a distinctive e4-related cognitive phenotype that is independent from clinical diagnostic status: findings from the Australian Imaging, Biomarkers and Lifestyle Study. Brain: a journal of neurology, 136(7), 2201-16. https://doi.org/10.1093/brain/awt127.
Lim, F., Lam, SM., Shui, G., Mondal, A., Ong, D., Duan, X., Creegan, R., Martins, I., Sharman, M., Taddei, K., Verdile, G., Wenk, M., Martins, R. (2013). Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E E3 and E4 knock-in mice. Neurobiology of Aging, 34(9), 2217-2224. https://doi.org/10.1016/j.neurobiolaging.2013.03.012.
Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, L., Szoeke, C., Rowe, C., Martins, R. (2013). Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18(8), 875-881. https://doi.org/10.1038/mp.2012.107.
Sharman, M., Moussavi Nik, S., Chen, M., Ong, D., Wijaya, L., Laws, S., Taddei, K., Newman, M., Lardelli, M., Martins, R., Verdile, G. (2013). The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related Genes. PLoS One, 8(6), e66235. https://doi.org/10.1371/journal.pone.0066235.
Doecke, J., Laws, S., Faux, N., Wilson, W., Burnham, S., Lam, P., Mondal, A., Bedo, J., Bush, A., Brown, B., De Ruyck, K., Ellis, K., Fowler, C., Gupta, V., Head, R., Macaulay, SL., Pertile, K., Rowe, C., Rembach, A., Rodrigues, M., Rumble, R., Szoeke, C., Taddei, K., Taddei, T., Trounson, B., Ames, D., Masters, C., Martins, R. (2012). Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease. Archives of Neurology, 69(10), 1318-1325. https://doi.org/10.1001/archneurol.2012.1282.
Sohrabi, H., Bates, K., Weinborn, M., Johnston, A., Bahramian, A., Taddei, K., Laws, S., Rodrigues, M., Morici, M., Howard, M., Martins, G., Mackay-Sim, A., Gandy, S., Martins, R. (2012). Olfactory discrimination predicts cognitive decline amongst community-dwelling older adults. Translational Psychiatry, 2(2012), art. no. e118. https://doi.org/10.1038/tp.2012.43.
Brown, B., Peiffer, J., Sohrabi, H., Mondal, A., Gupta, V., Rainey-Smith, S., Taddei, K., Burnham, S., Ellis, K., Szoeke, C., Masters, CL., Ames, D., Rowe, C., Martins, R. (2012). Intense physical activity is associated with cognitive performance in the elderly. Translational Psychiatry, 2(2012), art. no. e191. https://doi.org/10.1038/tp.2012.118.
Lau, S., Bates, K., Sohrabi, H., Rodrigues, M., Martins, G., Dhaliwal, S., Taddei, K., Laws, S., Martins, I., Mastaglia, F., Foster, J., Phillips, J., Martins, R. (2012). Functional effects of genetic polymorphism in inflammatory genes in subjective memory complainers. Neurobiology of Aging, 33(6), 1054-1056. https://doi.org/10.1016/j.neurobiolaging.2010.09.003.
Kirby, S., Gu, Y., Rainey-Smith, S., Keogh, JB., Clifton, PM., Mathieson, SL., Taddei, K., Mondal, A., Ward, V., Scarmeas, N., Barnes, M., Ellis, K., Head, R., Masters, C0., Ames, D., Macaulay, S0., Rowe, C0., Szoeke, C., Martins, R. (2012). Adherence to a Mediterranean diet and Alzheimer's disease risk in an Australian population. Translational Psychiatry, 2(2012), e164. https://doi.org/10.1038/tp.2012.91.
Sona, A., Zhang, P., Ames, D., Bush, AI., Lautenschlager, NT., Martins, R., Masters, CL., Rowe, CC., Szoeke, C., Taddei, K., Ellis, KA. (2012). Predictors of rapid cognitive decline in Alzheimer's disease: Results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of ageing. International Psychogeriatrics, 24(2), 197-204. https://doi.org/10.1017/S1041610211001335.
Wahjoepramono, EJ., Wijaya, L., Taddei, K., Bates, K., Howard, M., Martins, G., De Ruyck, K., Matthews, P., Verdile, G., Martins, R. (2011). Direct Exposure of Guinea Pig CNS to Human Luteinizing Hormone Increases Cerebrospinal Fluid and Cerebral Beta Amyloid Levels.. Neuroendocrinology: international journal for basic and clinical studies on neuroendocrine relationships, 94(4), 313-322. https://doi.org/10.1159/000330812.
Kanyenda, L., Verdile, G., Boulos, S., Krishnaswamy, S., Taddei, K., Meloni, BP., Mastaglia, FL., Martins, R. (2011). The dynamics of CD147 in Alzheimer's disease development and pathology. Journal of Alzheimer's Disease, 26(4), 593-605. https://doi.org/10.3233/JAD-2011-110584.
Faux, NG., Ellis, KA., Porter, L., Fowler, CJ., Laws, S., Martins, R., Pertile, K., Rembach, A., Rowe, CC., Rumble, RL., Szoeke, C., Taddei, K., Taddei, T., Trounson, BO., Villemagne, VL., Ward, V., Ames, D., Masters, CL., Bush, A. (2011). Homocysteine, Vitamin B12, and Folic Acid Levels in Alzheimer's Disease, Mild Cognitive Impairment, and Healthy Elderly: Baseline Characteristics in Subjects of the Australian Imaging Biomarker Lifestyle Study.. Journal of Alzheimer's Disease, 27(4), 909-922. https://doi.org/10.3233/JAD-2011-110752.
Gupta, V., Laws, S., Villemagne, V., Ames, D., Bush, A., Ellis, K., Lui, J., Masters, C., Rowe, C., Szoeke, C., Taddei, K., Martins, R. (2011). Plasma apolipoprotein e and Alzheimer disease risk: The AIBL study of aging. Neurology, 76(12), 1091-1098. https://doi.org/10.1212/WNL.0b013e318211c352.
Kajiwara, Y., Franciosi, S., Takahashi, N., Krug, L., Schmeidler, J., Taddei, K., Haroutunian, V., Fried, U., Ehrlich, M., Martins, R., Gandy, S. (2010). Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease. Molecular Neurodegeneration, 5(1), Article No.1.
Sharman, M., Shui, G., Fernandis, A., Lim, WL., Berger, T., Hone, E., Taddei, K., Martins, I., Ghiso, J., Buxbaum, JD., Gandy, S., Wenk, M., Martins, R. (2010). Profiling brain and plasma lipids in human APOE ε2, ε3 and ε4 knock-in mice using electrospray ionization mass spectrometry.. Journal of Alzheimer's Disease, 20(1), 105-111.
Lui, J., Laws, S., Li, Q., Villemagne, V., Ames, D., Brown, B., Bush, A., De Ruyck, K., Dromey, J., Ellis, K., Faux, N., Foster, J., Fowler, C., Gupta, V., Hudson, P., Laughton, K., Masters, C., Pertile, K., Rembach, A., Rimajova, M., Rodrigues, M., Rowe, C., Rumble, R., Szoecke, C., Taddei, K., Taddei, T., Trounson, B., Ward, V., Martins, R. (2010). Plasma amyloid-β as a biomarker in Alzheimer’s disease: the AIBL study of aging.. Journal of Alzheimer's Disease, 20(4), 1233-1242.
Sharman, M., Morici, M., Hone, E., Berger, T., Taddei, K., Martins, I., Lim, WL., Singh, S., Wenk, M., Ghiso, J., Buxbaum, JD., Gandy, S., Martins, R. (2010). APOE Genotype Results in Differential Effects on the Peripheral Clearance of Amyloid-ß42 in APOE Knock-in and Knock-out Mice. Journal of Alzheimer's Disease, 21(2), 403-409. https://doi.org/10.3233/JAD-2010-100141.
Barron, A., Verdile, G., Taddei, K., Bates, K., Martins, R. (2010). Effect of Chronic hCG Administration on Alzheimer's-Related Cognition and Aβ accumulation in PS1KI mice. Endocrinology, 151(11), 5380–5388.
Sohrabi, H., Bates, K., Rodrigues, M., Taddei, K., Martins, G., Laws, S., Lautenschlager, N., Dhaliwal, S., Foster, J., Martins, R. (2009). The relationship between memory complaints, perceived quality of life and mental health in apolipoprotein eε4 carriers and non-carriers. Journal of Alzheimer's disease, 17(1), 69-79.
Sohrabi, H., Bates, K., Rodrigues, M., Taddei, K., Laws, S., Lautenschlager, N., Dhaliwal, S., Johnston, A., Mackay-Sim, A., Gandy, S., Foster, J., Martins, R. (2009). Olfactory dysfunction is associated with subjective memory complaints in community-dwelling elderly individuals. Journal of Alzheimer's disease, 17(1), 135-142.
Ellis, K., Bush, A., Darby, D., De Fazio, D., Foster, J., Hudson, P., Lautenschlager, N., Lenzo, N., Martins, R., Maruff, P., Masters, C., Milner, A., Pike, K., Rowe, C., Savage, G., Szoeke, C., Taddei, K., Villemagne, V., Woodward, M., Ames, D., Aibl Research Group, T. (2009). The Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging: methodology and baseline characteristics of 1112 individuals recruited for a longitudinal study of Alzheimer's disease. International Psychogeriatrics, 21(4), 672-687.
Bates, K., Sohrabi, H., Rodrigues, M., Beilby, J., Dhaliwal, S., Taddei, K., Criddle, A., Wraith, M., Howard, M., Martins, G., Paton, A., Mehta, P., Foster, J., Martins, I., Launtenschlager, N., Mastaglia, F., Laws, S., Gandy, S., Martins, R. (2009). Association of Cardiovascular Factors and Alzhemer's Disease Plasma Amyloid-β Protein in subjective memory Complainers. Journal of Alzheimer's Disease, 17(2), 305-318.
Flicker, L., Martins, R., Thomas, J., Acres, J., Taddei, K., Vasikaran, S., Norman, P., Jamrozik, K., Almeida, O. (2008). B-Vitamins reduce plasma levels of beta amyloid. Neurobiology of Aging, 29(2), 303-305. https://doi.org/10.1016/j.neurobiolaging.2006.10.007.
Taddei, K., Laws, S., Verdile, G., Munns, S., D'costa, K., Harvey, A., Martins, I., Hill, F., Levy, E., Shaw, J., Martins, R. (2008). Novel phage peptides attenuate beta amyloid-42 catalysed hydrogen peroxide production and associated neurotoxicity. Neurobiology of Aging, n/a(n/a), 12 pages.
Wahjoepramono, EJ., Wijaya, L., Taddei, K., Martins, G., Howard, M., De Ruyck, K., Bates, K., Dhaliwal, S., Verdile, G., Carruthers, M., Martins, R. (2008). Distinct Effects of Testosterone on Plasma and Cerebrospinal Fluid Amyloid-beta Levels. Journal of Alzheimer's Disease, 15(1), 129-137.
Gnjec, A., D'costa, K., Laws, S., Hedley, R., Balakrishnan, K., Taddei, K., Martins, G., Paton, A., Verdile, G., Gandy, S., Broe, A., Brooks, W., Bennett, H., Piguet, O., Price, P., Miklossy, J., Hallmayer, J., McGeer, P., Martins, R. (2008). Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. Journal of Neuroinflammation, 5(36), 1-10. https://doi.org/10.1186/1742-2094-5-36.
Flicker, L., Martins, R., Thomas, J., Acres, J., Taddei, K., Norman, P., Jamrozik, K., Almeida, O. (2004). Homocysteine, Alzheimer genes and proteins, and measures of cognition and depression in older men. Journal of Alzheimer's disease, 6(3), 329-336.
Dean, B., Laws, S., Hone, E., Taddei, K., Scarr, E., Thomas, E., Harper, C., McClean, C., Masters, C., Lautenschlager, N., Gandy, S., Martins, R. (2003). Increased levels of apolipoprotein E in the frontal cortex of subjects with schizophrenia. Biological Psychiatry, 54(6), 616-622.
Miklossy, J., Taddei, K., Suva, D., Verdile, G., Fonte, J., Fisher, C., Gnjec, A., Ghika, J., Suard, F., Mehta, P., McLean, C., Masters, C., Brooks, W., Martins, R. (2003). Two novel presenilin-1 mutations (Y256S and Q222H) are associated with early-onset Alzheimer's disease. Neurobiol Aging, 24(5), 655-662.
Research Projects
AIBL: Agreement with Biogen for provision of AIBL Data and samples, Florey Institute of Neuroscience and Mental Health, Grant, 2016 ‑ 2022, $3,108,475.
Sponsorship of Research Fellow (Eugene Hone, Prashant Bharadwaj, Steve Pedrini), Lions Alzheimer's Foundation, Sponsorship, 2021, $420,378.
WA Memory Study (WAMS), Australian Alzheimer's Research Foundation, McCusker Alzheimer's Research Foundation - Grant, 2019 ‑ 2021, $236,746.
Sponsorship of Research Fellow (Kevin Taddei), Australian Alzheimer's Research Foundation, Australian Alzheimer's Research Foundation - Sponsorship, 2021, $190,000.
Sponsorship of Research Fellow (Kevin Taddei), Australian Alzheimer's Research Foundation, Australian Alzheimer's Research Foundation - Sponsorship, 2020, $210,393.
Sponsorship Agreement Post-Doctoral Research Fellow, Australian Alzheimer's Research Foundation, Neuroscience Research Institute - Sponsorship, 2018 ‑ 2019, $94,922.
Sponsorship of Research Fellow (Georgina Martins), Australian Alzheimer's Research Foundation, Australian Alzheimer's Research Foundation - Sponsorship, 2019, $25,468.
Sponsorship of Research Fellow (Hamid Soharbi), Australian Alzheimer's Research Foundation, Australian Alzheimer's Research Foundation - Sponsorship, 2019, $47,130.
Sponsorship of Research Fellow (Kevin Taddei), Australian Alzheimer's Research Foundation, Australian Alzheimer's Research Foundation - Sponsorship, 2019, $90,198.
Head Injury and Testosterone (HIT), Harry Perkins Institute of Medical Research, Neurotrauma Research Program, 2013 ‑ 2017, $148,701.
Ocular Imaging Project NeuroVision Imaging, Commonwealth Scientific and Industrial Research Organisation (CSIRO), NeuroVision Imaging, LLC Grant, 2013 ‑ 2015, $152,999.
Establishing a combined ocular and blood biomarker panel for Alzheimer’s disease., Australian National University, ANU - Dementia CRC - Grant, 2014 ‑ 2015, $517,977.
A study of the kinetics of biomarkers and their presumptive relationship with brain amyloid , Commonwealth Scientific and Industrial Research Organisation (CSIRO), Araclon Biotech , 2014 ‑ 2015, $132,200.
CSIRO/Janssen AIBL Neuroscience Program, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Janssen Neuroscience Program, 2014 ‑ 2015, $200,000.
Dementia Collaborative Research Council - Lipid Profiles in Alzheimer's Disease, Australian National University, ANU - Dementia CRC - Grant, 2011 ‑ 2014, $90,000.
Peripheral Clearance of Amyloid-beta (Aβ) using Novel Binding Peptides, Alzhyme Pty Ltd, Grant, 2011 ‑ 2014, $600,000.
Proteomics for discovery of novel biomarkers, Australian National University, ANU - Dementia CRC - Grant, 2011 ‑ 2013, $74,045.
The Australian Imaging, Biomarker and Lifestyle Study of Ageing - Round 2, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Science Industry Endowment Fund Agreement, 2010 ‑ 2013, $2,013,000.
Assess suitability of multiplexing, Australian National University, ANU - Dementia CRC - Grant, 2011 ‑ 2013, $198,755.
Enhancing Peripheral Clearance of Beta Amyloid as a Treatment of Alzheimer's Disease, National Health and Medical Research Council, Grant, 2010 ‑ 2013, $529,125.
Evaluation of candidate biomarkers in platelets, Australian National University, ANU - Dementia CRC - Grant, 2011 ‑ 2012, $67,990.
Neon Transfection System and Biomedical Research Grade -30oC Freezer for Alzheimer’s and Melanoma Research, National Health and Medical Research Council, Equipment Grant 2011, 2011 ‑ 2012, $10,927.
Dementia Collaborative Research Centre (Round2): Early Diagnosis and Prevention - PROJECT 3 (ECUPO3) - Plasma IDE Measurement, Department of Health, Grant, 2010 ‑ 2011, $187,075.
Dementia Collaborative Research Centre (Round2): Early Diagnosis and Prevention - PROJECT 2 (ECUPO2) - Plasma apoE Measurement, Department of Health, Grant, 2010 ‑ 2011, $100,674.
-30C Freezer for Increased Tissue/Blood Storage Capacity in the Alzheimer's Disease Research Laboratory, Edith Cowan University, Grant, 2007 ‑ 2008, $12,266.
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