Top of page
Global Site Navigation

School of Medical and Health Sciences

Local Section Navigation

Help us improve our content by rating this page.

Page rating system

Please leave a comment about your rating so we can better understand how we might improve the page.

You are here: Main Content

Dr Veer Gupta

Adjunct Associate Professor

Contact Information Email:,
Staff Member Details


Veer is an Adjunct Associate Professor within the School of Medical and Health Sciences.


  • Doctor of Philosophy in Bio-Chemistry, India, 2009.
  • Master of Science Biochemistry, India, 2002.
  • Bachelor of Science, India, 2001.


Recent Research Grants

  • Establishing a blood-based biomarker panel for pre-clinical Alzheimer's disease,  National Health and Medical Research Council,  Boosting Dementia Research Leadership Fellowship Scheme,  2018 - 2022,  $716,778.
  • Blood biomarkers for the diagnosis of pre-clinical Alzheimer’s disease employing the Dominantly Inherited Alzheimer Network cohort,  National Health and Medical Research Council,  Project Grants,  2017 - 2021,  $1,125,804.
  • Developing a blood-based biomarker panel for Alzheimer's disease,  BrightFocus Foundation,  Alzheimer's Disease Research - Postdoctoral Fellowship Awards,  2015 - 2018,  $126,876.
  • 4.4B1 Novel Therapeutics for AD Testosterone Trial,  CRC For Mental Health,  CRC Grant,  2011 - 2018,  $1,068,045.
  • Infrastructure Award,  Department of Health WA,  SHRAC - New Independent Researcher Infrastructure Support Award,  2015 - 2017,  $10,000.
  • Investigating peripheral biochemical changes during familial Alzheimer s disease progression.,  Dementia Australia Research Foundation,  AADRF - Dementia Grants Program,  2016 - 2017,  $50,000.
  • Establishing a combined ocular and blood biomarker panel for Alzheimer’s disease.,  Australian National University,  ANU - Dementia CRC - Grant,  2014 - 2015,  $517,977.
  • Discovery and Validation of Alzheimer's disease biomarkers in human plasma,  National Health and Medical Research Council,  Project Grants,  2011 - 2014,  $352,524.
  • An innovative approach to identify specific biomarkers for early diagnosis of Alzheimer's disease,  Australian National University,  ANU - Dementia CRC - Grant,  2013 - 2014,  $115,000.
  • Nuclear magnetic resonance spectroscopy facilities – Advancing cutting-edge chemical, biological, energy and materials research in Western Australia,  Australian Research Council,  Grant - Linkage (Infrastructure),  2014,  $1,666,000.
  • Initiating an Indo-Australian cooperation for early diagnosis and prediction in the aged population: Partnering the universities for a tactical approach to Alzheimer's disease and other neurodegenerative conditions,  Department of Foreign Affairs and Trade,  Australia-India Council,  2011 - 2013,  $4,000.
  • The Australian Imaging, Biomarker and Lifestyle Study of Ageing - Round 2,  Commonwealth Scientific and Industrial Research Organisation (CSIRO),  Science Industry Endowment Fund Agreement,  2010 - 2013,  $5,341,586.
  • Investigating the Association Between APOE Promoter Polymorphisms and Plasma APOE levels: A Blood Test for Alzheimer’s Disease.,  Edith Cowan University,  ECU Early Career Researcher - Grant,  2009 - 2010,  $24,830.

Recent Publications (within the last five years)

Journal Articles

  • Martins, R., Villemagne, V., Sohrabi, H., Chatterjee, P., Shah, T., Verdile, G., Fraser, P., Taddei, K., Gupta, V., Rainey-Smith, S., Hone, E., Pedrini, S., Lim, F., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K., Fuller, S., Brown, B., Gardener, S., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S., Barron, A., Goozee, K., Wahjoepramono, EJ., Asih, P., Doecke, J., Salvado, O., Bush, A., Rowe, C., Gandy, S., Masters, C., (2018), Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease, 62(3), 965-992, Netherlands, IOS Press, DOI: 10.3233/JAD-171145.
  • Fernando, B., Rainey-Smith, S., Gardener, S., Villemagne, V., Burnham, S., Macaulay, SL., Brown, B., Gupta, V., Sohrabi, H., Weinborn, M., Taddei, K., Laws, S., Goozee, K., Ames, D., Fowler, C., Maruff, P., Masters, C., Salvado, O., Rowe, C., Martins, R., (2018), Associations of dietary protein and fiber intake with brain and blood amyloid-B. Journal of Alzheimer's Disease, 61(2018), 1589-1598, Netherlands, IOS Press, DOI: 10.3233/JAD-170742.
  • O'Bryan, S., Mielke, M., Rissman, R., Lista, S., Vanderstichele, H., Zetterberg, H., Lewczuk, P., Posner, H., Hall, J., Johnson, L., Fong, Y., Luthman, J., Jeromin, A., Batrla-Utermann, R., Villarreal, A., Britton, G., Snyder, P., Henriksen, K., Grammas, P., Gupta, V., Martins, R., Hampel, H., (2017), Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic. Alzheimer's and Dementia, 13(1), 45-58, United States, Elsevier Science Inc., DOI: 10.1016/j.jalz.2016.09.014.
  • Pedrini, S., Gupta, V., Hone, E., Doecke, J., O’bryant, S., James, I., Bush, AI., Rowe, CC., Villemagne, VL., Ames, D., Masters, CL., Martins, R., (2017), A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of beta-amyloid load in an AD cohort. Scientific Reports, 7(OCT 25 2017), Article number 14057, DOI: 10.1038/s41598-017-14020-9.
  • Chitranshi, N., Dheer, Y., Gupta, V., Abbasi, M., Mirzaei, M., You, Y., Chung, R., Graham, S., Gupta, V., (2017), PTPN11 induces endoplasmic stress and apoptosis in SH-SY5Y cells. Neuroscience, 364(2017), 175-189, DOI: 10.1016/j.neuroscience.2017.09.028.
  • Lim, YY., Rainey-Smith, S., Lim, Y., Laws, S., Gupta, V., Porter, T., Bourgeat, P., Ames, D., Fowler, C., Salvado, O., Villemagne, V., Rowe, C., Masters, C., Zhou, XF., Martins, R., Maruff, P., (2017), BDNF Val66Met in preclinical Alzheimer’s disease is associated with short-term changes in episodic memory and hippocampal volume but not serum mBDNF. International Psychogeriatrics, 29(11), 1825-1834, Cambridge, United Kingdom, Cambridge University Press, DOI: 10.1017/S1041610217001284.
  • Gupta, V., Hone, E., Pedrini, S., Doecke, J., O'Bryant, S., James, I., Bush, A., Rowe, C., Villemagne, V., Ames, D., Masters, C., Martins, R., (2017), Altered levels of blood proteins in Alzheimer’s disease longitudinal study: Results from Australian Imaging Biomarkers lifestyle study of ageing cohort. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 8(2017), 60-72, United States, Elsevier Science Inc., DOI: 10.1016/j.dadm.2017.04.003.
  • Chitranshi, N., Dheer, Y., Vander Wall, R., Gupta, V., Abbasi, M., Graham, S., Gupta, V., (2017), Computational analysis unravels novel destructive single nucleotide polymorphisms in the non-synonymous region of human caveolin gene. Gene Reports, 6(1 March), 142-157, Elsevier, DOI: 10.1016/j.genrep.2016.08.008.
  • Gupta, V., Mirzaei, M., Gupta, V., Chitranshi, N., Dheer, Y., Vanderwall, R., Abbasi, M., You, Y., Chung, R., Graham, S., (2017), Glaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin. Scientific Reports, 7(8412), 18p., United Kingdom, Nature Publishing Group, DOI: 10.1038/s41598-017-08688-2.
  • Mirzaei, M., Gupta, V., Chick, JM., Greco, TM., Wu, Y., Chitranshi, N., Vander Wall, R., Hone, E., Deng, L., Dheer, Y., Abbasi, M., Rezaeian, M., Braidy, N., You, Y., Hosseini Salekdeh, G., Haynes, PA., Molloy, MP., Martins, R., Cristea, IM., Gygi, SP., Graham, SL., Gupta, VK., (2017), Age-related neurodegenerative disease associated pathways identified in retinal and vitreousproteome from human glaucoma eyes. Scientific Reports, 7(1), Article number 12685, Lonon, United Kingdom, Nature Publishing Group, DOI: 10.1038/s41598-017-12858-7.
  • Rainey-Smith, S., Brown, B., Sohrabi, H., Shah, T., Goozee, K., Gupta, V., Martins, R., (2016), Curcumin and cognition: a randomized, placebo-controlled, double-blind study of community-dwelling older adults. British Journal of Nutrition, 115(2), 2106-2113, Cambridge University Press, DOI: 10.1017/S0007114516001203.
  • Chatterjee, P., Lim, F., Shui, G., Gupta, V., James, I., Fagan, A., Xiong, C., Sohrabi, H., Taddei, K., Brown, B., Benzinger, T., Masters, C., Snowden, S., Wenk, M., Bateman, R., Morris, J., Martins, R., (2016), Plasma Phospholipid and Sphingolipid Alterations in Presnilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's disease, 50(3), 887-894, Netherlands, IOS Press, DOI: 10.3233/JAD-150948.
  • Bird, S., Sohrabi, H., Sutton, T., Weinborn, M., Rainey-Smith, S., Brown, B., Patterson, L., Taddei, K., Gupta, V., Carruthers, M., Lenzo, N., Knuckey, N., Bucks, R., Verdile, G., Martins, R., (2016), Cerebral amyloid-β accumulation and deposition following traumatic brain injury-A narrative review and meta-analysis of animal studies. Neuroscience & Biobehavioural Reviews, 64(2016), 215-228, Elsevier Ltd, DOI: 10.1016/j.neubiorev.2016.01.004.
  • O'Bryant, S., Lista, S., Rissman, R., Edwards, M., Zhang, F., Hall, J., Zetterberg, H., Lovestone, S., Gupta, V., Graff-Radford, N., Martins, R., Jeromin, A., Waring, S., Oh, E., Kling, M., Baker, L., Hampel, H., (2016), Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges. Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring, 3(2016), 27-34, Elsevier, DOI: 10.1016/j.dadm.2015.12.003.
  • Chitranshi, N., Gupta, V., Dheer, Y., Gupta, V., Vander Wall, R., Graham, S., (2016), Molecular determinants and interaction data of cyclic peptide inhibitor with the extracellular domain of TrkB receptor. Data in Brief, 6(March 2016), 776-782, Elsevier, DOI: 10.1016/j.dib.2016.01.016.
  • Gupta, V., Doecke, J., Hone, E., Pedrini, S., Laws, S., Thambisetty, M., Bush, A., Rowe, C., Villemagne, V., Ames, D., Masters, C., Macaulay, SL., Rembach, A., Rainey-Smith, S., Martins, R., (2016), Plasma apolipoprotein J as a potential biomarker for Alzheimer's disease: Australian Imaging, Biomarkers and Lifestyle study of aging. Alzheimers and Dementia: Diagnosis, Assessment & Disease Monitoring, 3(2016), 18-26, Elsevier Inc., DOI: 10.1016/j.dadm.2015.12.001.
  • Muenchhoff, J., Poljak, A., Thalamuthu, A., Gupta, V., Chatterjee, P., Raffery, M., Masters, C., Morris, J., Bateman, J., Fagan, A., Martins, R., Sachdev, P., (2016), Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease. Science Reports, 6(2016), Article no. 29078, Nature Publishing Group, DOI: 10.1038/srep29078.
  • Gupta, V., Gupta, V., (2016), Using Technology, Bioinformatics and Health Informatics Approaches to Improve Learning Experiences in Optometry Education, Research and Practice. Healthcare, 4(86), 12p., Switzerland, MDPI, DOI: 10.3390/healthcare4040086.
  • Barr, R., Verdile, G., Wijaya, L., Morici, M., Taddei, K., Gupta, V., Pedrini, S., Jin, L., Nicolazzo, JA., Knock, E., Fraser, P., Martins, R., (2016), Validation and characterization of a novel peptide that binds monomeric and aggregated β-Amyloid and inhibits the formation of neurotoxic oligomers. Journal of Biological Chemistry, 291(2), 547-559, Bethesda, USA, American Society for Biochemistry and Molecular Biology, Inc., DOI: 10.1074/jbc.M115.679993.
  • Gupta, V., Gupta, V., Chitranshi, N., Gangoda, S., Vander Wall, R., Abbasi, M., Golzan, M., Dheer, Y., Shah, T., Avolio, A., Chung, R., Martins, R., Graham, S., (2016), One protein, multiple pathologies: multifaceted involvement of amyloid β in neurodegenerative disorders of the brain and retina. Cellular and Molecular Life Sciences, 73(22), 4279-4297, Birkhauser Verlag AG, DOI: 10.1007/s00018-016-2295-x.
  • Gupta, V., Chitranshi, N., Gupta, V., Golzan, M., Dheer, Y., Vander Wall, R., Georgevsky, D., King, A., Vickers, JC., Chung, R., Graham, S., (2016), Amyloid β accumulation and Inner retinal degenerative changes in Alzheimer’s disease transgenic mouse. Neuroscience Letters, 623(2016), 52-56, Elsevier, DOI: 10.1016/j.neulet.2016.04.059.
  • O'Bryant, SE., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J., Schupf, N., Rissman, R., Fagan, A., Oberoi, P., Umek, R., Weiner, M., Grammas, P., Posner, H., Martins, R., (2015), Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research. Alzheimer's and Dementia, 11(5), 549-560, United States, Elsevier Inc., DOI: 10.1016/j.jalz.2014.08.099.
  • Chatterjee, P., Gupta, V., Fagan, A., Jasielec, M., Xiong, C., Sohrabi, H., Dhaliwal, S., Taddei, K., Bourgeat, P., Brown, B., Benzinger, T., Bateman, R., Morris, J., Martins, R., (2015), Decreased Platelet APP Isoform Ratios in Autosomal Dominant Alzheimer's Disease: Baseline Data from a DIAN Cohort Subset. Current Alzheimer Research, 12(2), 157-164, Bussum, Netherlands, Bentham Science Publishers, DOI: 10.2174/1567205012666150204125732.
  • Xu, H., Gupta, V., Martins, I., Martins, R., Fowler, CJ., Bush, AI., Finkelstein, DI., Adlard, PA., (2015), Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way. Neurobiology of Disease, 81(September 2015), 38-48, Elsevier, DOI: 10.1016/j.nbd.2015.06.016.
  • Gupta, V., Wilson, A., Burnham, S., Hone, E., Pedrini, S., Laws, S., Lim, F., Rembach, A., Rainey-Smith, S., Ames, D., Cobiac, L., Macaulay, SL., Masters, C., Rowe, C., Bush, A., Martins, R., (2015), Follow-up plasma apolipoprotein E levels in the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing (AIBL) cohort. Alzheimer's Research and Therapy, 7(1), Article no.16, United Kingdom, BioMed Central Ltd., DOI: 10.1186/s13195-015-0105-6.
  • Gupta, V., Chitranshi, N., You, Y., Gupta, V., Klistorner, A., Graham, S., (2014), Brain derived neurotrophic factor is involved in the regulation of glycogen synthase kinase 3β (GSK3β) signalling. Biochemical and Biophysical Research Communications, 454(3), 381-386, Academic Press Inc., DOI: 10.1016/j.bbrc.2014.10.087.
  • Verdile, G., Laws, S., Henley, D., Ames, D., Bush, A., Ellis, K., Faux, N., Gupta, V., Li, Q., Masters, C., Pike, K., Rowe, C., Szoeke, C., Taddei, K., Villemagne, V., Martins, R., (2014), Associations between gonadotropins, testosterone and β amyloid in men at risk of Alzheimer's disease. Molecular Psychiatry, 19(1), 69-75, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2012.147.
  • Asih, P., Chatterjee, P., Verdile, G., Gupta, V., Trengove, RD., Martins, R., (2014), Clearing the amyloid in Alzheimers: progress towards earlier diagnosis and effective treatments - an update for clinicians. Neurodegenerative Disease Management, 4(5), 363-378, London, United Kingdom, Future Medicine Ltd, DOI: 10.2217/nmt.14.29.
  • Martins, I., Gupta, V., Wilson, A., Fuller, SJ., Martins, R., (2014), Interactions Between Apo E and Amyloid Beta and their Relationship to Nutriproteomics and Neurodegeneration. Current Proteomics: the journal for current and in-depth reviews on proteomics, 11(3), 171-183, Netherlands, Bentham Science Publishers.
  • Gupta, V., You, Y., Li, J., Gupta, V., Golzan, M., Klistorner, A., Van Den Buuse, M., Graham, S., (2014), BDNF impairment is associated with age-related changes in the inner retina and exacerbates experimental glaucoma. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1842(9), 1567-1578, Elsevier, DOI: 10.1016/j.bbadis.2014.05.026.
  • O' Bryant, S., Xiao, G., Edwards, M., Devous, M., Gupta, V., Martins, R., Zhang, F., Barber, R., (2013), Biomarkers of Alzheimer’s Disease Among Mexican Americans. Journal of Alzheimer's Disease, 34(4), 841-849, Netherlands, IOS Press, DOI: 10.3233/JAD-122074.
  • Steele, JW., Lachenmayer, ML., Ju, S., Stock, A., Liken, J., Kim, SH., Delgado, LM., Alfaro, IE., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Fraser, P., Westaway, D., St George-Hyslop, P0., Szabo, P., Relkin, N0., Buxbaum, J0., Glabe, C0., Protter, A0., Martins, R., Ehrlich, M0., Petsko, G0., (2013), Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Molecular Psychiatry, 18(8), 889-897, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2012.106.
  • Gupta, V., Monica, F., Berrocal, R., Rao, KS., Rao, K., (2013), Studies on the mechanism of the DNA nicking property of amyloid-β40: implications in Alzheimer's disease. Journal of Alzheimer's Disease, 33(4), 1059-1071, Netherlands, IOS Press, DOI: 10.3233/JAD-121249.
  • Steele, JW., Ju, S., Lachenmayer, M., Liken, J., Stock, A., Kim, SH., Delgado, L., Alfaro, I., Bernales, S., Verdile, G., Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S., (2013), Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain. Molecular Psychiatry, 18(8), 882-888, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2012.115.
  • Gupta, V., Sundaram, R., Martins, R., (2013), Multiplex biomarkers in blood. Alzheimer's Research & Therapy, 5(3), Article 31, United Kingdom, BioMed Central, DOI: 10.1186/alzrt185.
  • Gupta, V., You, Y., Gupta, V., Klistorner, A., Graham, S., (2013), TrkB receptor signalling: Implications in neurodegenerative, psychiatric and proliferative disorders. International Journal of Molecular Sciences, 14(5), 10122-10142, Basel, Switzerland, M D P I AG, DOI: 10.3390/ijms140510122.
  • Brown, B., Peiffer, J., Taddei, K., Lui, J., Laws, S., Gupta, V., Taddei, T., Ward, V., Rodrigues, M., Burnham, S., Rainey-Smith, S., Villemagne, V., Bush, A., Ellis, K., Masters, C., Ames, D., Macaulay, L., Szoeke, C., Rowe, C., Martins, R., (2013), Physical activity and amyloid-β plasma and brain levels: results from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing. Molecular Psychiatry, 18(8), 875-881, United Kingdom, Nature Publishing Group, DOI: 10.1038/mp.2012.107.

Research Student Supervision

Associate Supervisor

Skip to top of page