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Dr Marc Sim

Senior Research Fellow

Staff Member Details
Email: marc.sim@ecu.edu.au
Campus: Joondalup  
ORCID iD: https://orcid.org/0000-0001-5166-0605

Background

Marc is a Senior Research Fellow in the School of Medical and Health Sciences within the Nutrition and Health Innovation Research Institute (NHIRI). He established and leads the Falls Free Future Program within NHIRI and is the Deputy Lead for the Disorders of Mineralisation Research Group at ECU. Marc currently holds Fellowships from the Royal Perth Hospital Research Foundation and Department of Health (WA). Marc’s research program examines the role of nutrition, physical activity and its impact on disease progression, more specifically musculoskeletal function and structure. His research is targeted at reducing falls and associated injuries (e.g. fracture) in older populations.

Marc received his PhD (Deans List) from The University of Western Australia in March 2015. Marc’s doctoral research investigated the effect of exercise on inflammation and iron metabolism. He is an accredited Exercise and Sport Scientist (Level 2) and registered Nutritionist. Previously, Marc worked in industry as a Sports Physiologist at the Western Australian Institute of Sport. Marc’s musculoskeletal research program is based at the Royal Perth Hospital Research Foundation and is supported by his expertise in the design, coordination and conduct of RCTs, as well as advanced biostatistics specific to large cohort studies. Marc serves on the Council for the Australia and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR), Research Committee for the Australian and New Zealand Bone and Mineral Society (ANZBMS), and the Publications Committee for Exercise and Sports Science Australia (ESSA). Marc is part of the ANZSSFR Taskforce which operationalised a definition for sarcopenia currently used nationally.

Awards and Recognition

  • 2023 European Calcified Tissue Society Allied Health Award
  • 2023 European Calcified Tissue Society Best Clinical Poster Forum Award: Dietary Vitamin K1 intake is associated with lower long-term injurious fall and fracture risk: The Perth Longitudinal Study of Ageing Women
  • 2022 Royal Perth Hospital Research Foundation, Best Publication for an Early Career Researcher "Abdominal aortic calcification on lateral spine images captured during bone density testing and late-life dementia risk in older women"
  • 2022 Western Australia Cardiovascular Researchers Alliance, Best Publication Prize by an Early Career Researcher: "Abdominal aortic calcification on lateral spine images captured during bone density testing and late-life dementia risk in older women"
  • 2022 World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Disease.  International Osteoporosis Foundation Nutrition Award: "Dietary Vitamin K1 intake is associated with lower long-term fracture-related hospitalisation risk: the Perth Longitudinal Study of Ageing Women.
  • 2021 Bridging Overseas Networking and Exchange (B.O.N.E) program exchange with the Bone Research Society (UK).  Selected representative for the Australian and New Zealand Bone and Mineral Society.
  • 2021 Australian and New Zealand Bone and Mineral Society, Kyowa Kirin Best Clinical Presentation: "Creatinine to cystatin C ratio: a novel biomarker of sarcopenia measures and falls risk in community-dwelling older women?".
  • Edith Cowan University Early and Mid-Career Researcher Network (EMCRN) Symposium 2020, Best Presentation for Research in Health.  Higher dietary nitrate intake is associated with better muscle function in men and women independent of physical activity levels.
  • Australia and New Zealand Society for Sarcopenia and Frailty Research Bright Star Publication Award for the paper titled: 'Higher dietary nitrate intake is associated with better muscle function in older women', 2019.
  • Australian and New Zealand Bone and Mineral Society Travel Award, 2019.
  • Australian Postgraduate Award, 2010-2014.
  • Bruce and Betty Green Science Prize, The University of Western Australia, 2010.
  • Postgraduate Research Travel Award, The University of Western Australia, 2011 & 2013.
  • Edith Cowan University Platinum Prize, Australian Society for Medical Research Symposium. For the oral presentation entitled: ‘Effect of exercise modality and intensity on post-exercise interleukin-6 and hepcidin levels’, 2012.
  • The University of Western Australia Deans List Award for the Doctoral Thesis: ‘Effect of exercise on inflammation, hepcidin regulation and iron metabolism’, 2014.
  • Valedictorian, The University of Western Australia, March 2015.

Research Areas and Interests

  • Fall and fracture prevention in older populations
  • Benefits of physical activity and nutrition on the vasculature as well as musculoskeletal function/structure
  • Nutritional supplements to improve human performance
  • Iron regulation in active populations

Qualifications

  • Doctor of Philosophy, The University of Western Australia, 2015.

Research Outputs

Journal Articles

  • Webster, J., Dalla Via, J., Langley , C., Smith, C., Sale, C., Sim, M. (2023). Nutritional strategies to optimise musculoskeletal health for fall and fracture prevention: looking beyond calcium, vitamin D and protein. Bone Reports, -(-), -. https://doi.org/-.
  • Sim, M., Smith, C., Bondonno, N., Radavelli Bagatini, S., Blekkenhorst, L., Dalla Via, J., McCormick, R., Kun, Z., Hodgson, J., Prince, R., Lewis, J. (2023). Higher dietary Vitamin K intake is associated with better physical function and lower long-term injurious falls risk in community-dwelling older women. Journal of Nutrition, Health and Aging, -(-), -. https://doi.org/10.1007/s12603-022-1866-9.
  • Tan, J., Ng, C., Hart, N., Rantalainen, T., Sim, M., Scott, D., Zhu, K., Chivers, P. (2023). Reduced Peak Bone Mass in Young Adults with Low Motor Competence. Journal of Bone and Mineral Research, -(-), -.
  • Radavelli Bagatini, S., Macpherson, H., Scott, D., Daly, R., Hodgson, J., Laws, S., Zhu, K., Prince, R., Lewis, J., Sim, M. (2023). Impaired muscle function, including its decline, is related to greater long-term late-life dementia risk in older women. Journal of Cachexia, Sarcopenia and Muscle, in-press(-), -.
  • Bondonno, C., Zhong, L., Bondonno, N., Sim, M., Blekkenhorst, L., Liu, A., Rajendra, A., Pokharel, P., Erichsen, D., Neubauer, O., Croft, K., Hodgson, J. (2023). Nitrate: The Dr. Jekyll and Mr. Hyde of human health?. Trends in Food Science and Technology, 135(TBD), 57-73. https://doi.org/10.1016/j.tifs.2023.03.014.

Journal Articles

  • Zanker, J., Sim, M., Anderson, K., Balogun, S., Brennan-Olsen, S., Dent, E., Duque, G., Girgis, C., Grossmann, M., Hayes, A., Henwood, T., Hirani, V., Inderjeeth, C., Iuliano, S., Keogh, J., Lewis, J., Lynch, G., Pasco, J., Phu, S., Reijnierse, E., Russell, N., Vlietstra, L., Visvanathan, R., Walker, T., Waters, D., Yu, S., Maier, A., Daly, R., Scott, D. (2022). Consensus guidelines for sarcopenia prevention, diagnosis and management in Australia and New Zealand. Journal of Cachexia, Sarcopenia and Muscle, 2022(Article in Press), TBD. https://doi.org/10.1002/jcsm.13115.
  • Zhong, L., Blekkenhorst, L., Bondonno, N., Sim, M., Woodman, R., Croft, K., Lewis, J., Hodgson, J., Bondonno, C. (2022). A food composition database for assessing nitrate intake from plant-based foods. Food Chemistry, 394(15 November 2022), article number 133411. https://doi.org/10.1016/j.foodchem.2022.133411.
  • Ng, C., Scott, D., Sim, M., Zhu, K., Siafarikas, A., Hart, N., Tan, J., Chivers, P. (2022). Physical Activity Estimated by Osteogenic Potential and Energy Expenditure Has Differing Associations with Bone Mass in Young Adults: The Raine Study. Archives of Osteoporosis, 17(1), Article Number 67. https://doi.org/10.1007/s11657-022-01100-1.
  • Sim, M., Strydom, A., Blekkenhorst, L., Bondonno, N., McCormick, R., Lim, W., Zhu, K., Byrnes, E., Hodgson, J., Lewis, J., Prince, R. (2022). Dietary Vitamin K1 intake is associated with lower long-term fracture-related hospitalization risk: the Perth longitudinal study of ageing women. Food & Function, 13(20), 10642-10650. https://doi.org/10.1039/D2FO02494B.
  • Zhong, L., Liu, A., Blekkenhorst, L., Bondonno, N., Sim, M., Woodman, R., Croft, K., Lewis, J., Hodgson, J., Bondonno, C. (2022). Development of a food composition database for assessing nitrate and nitrite intake from animal-based foods. Molecular Nutrition and Food Research, 66(1), Article number 2100272. https://doi.org/10.1002/mnfr.202100272.
  • McCaskie, C., Sim, M., Newton, R., Heasman, J., Rogalski, B., Hart, N. (2022). Pre-season body composition is associated with in-season player availability in elite male Australian footballers. Journal of Strength and Conditioning Research, 2022(Article in press), 10 pages. https://doi.org/10.1519/JSC.0000000000004368.
  • Bellinge, J., Francis, R., Lee , S., Bondonno, N., Sim, M., Lewis, J., Watts, G., Schultz, C. (2022). The effect of vitamin K1 on arterial calcification activity in subjects with diabetes mellitus; A post-hoc analysis of a double-blind randomized placebo-controlled trial. American Journal of Clinical Nutrition, 115(1), 45-52. https://doi.org/10.1093/ajcn/nqab306.
  • Dalla Via, J., Sim, M., Schousboe, JT., Kiel, DP., Zhu, K., Hodgson, J., Gebre, A., Daly, RM., Prince, RL., Lewis, J. (2022). Association of abdominal aortic calcification with peripheral quantitative computed tomography bone measures in older women: The Perth Longitudinal Study of Ageing Women. Calcified Tissue International, 111(5), 485–494. https://doi.org/10.1007/s00223-022-01016-5.
  • Gebre, A., Lewis, J., Leow, K., Szulc, P., Scott, D., Sim, M., Ebeling, P., Wong , G., Lim, WH., Schousboe, JT., Kiel, DP., Prince, RL., Rodriguez, A. (2022). Abdominal aortic calcification, bone mineral density and fractures: a systematic review and meta-analysis of observational studies. Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 2022(article in press), 1-8. https://doi.org/10.1093/gerona/glac171.
  • Lundy , B., McKay , A., Fensham, N., Tee, N., Anderson, B., Morabito, A., Ross, M., Sim, M., Ackerman, K., Burke, L. (2022). The Impact of Acute Calcium Intake on Bone Turnover Markers during a Training Day in Elite Male Rowers. Medicine and Science in Sports and Exercise, 2022(article in press), 1-40. https://doi.org/10.1249/MSS.0000000000003022.
  • Adu, D., Bondonno, C., Parmenter, B., Sim, M., Davey, R., Murray, K., Radavelli Bagatini, S., Magliano, D., Daly, R., Shaw, J., Lewis, J., Hodgson, J., Bondonno, N. (2022). Association between non-tea flavonoid intake and risk of type 2 diabetes: the Australian Diabetes, Obesity and Lifestyle Study. Food & Function, 13(8), 4459-4468. https://doi.org/10.1039/d1fo04209b.
  • Smith, C., Hiam, D., Tacey, A., Lin, X., Woessner, M., Zarekookandeh, N., Garnham, A., Chubb, P., Lewis, J., Sim, M., Herrmann, M., Duque, G., Levinger, I. (2022). Higher bone remodeling biomarkers are related to a higher muscle function in older adults: Effects of acute exercise. Bone, 165(2022), article number 116545. https://doi.org/10.1016/j.bone.2022.116545.
  • Gebre, A., Sim, M., Dalla Via, J., Rodríguez, AJ., Zhu, K., Schousboe, JT., Hodgson, J., Bondonno, C., Prince, RL., Lewis, J. (2022). Cardiovascular disease, muscle function, and long-term falls risk: The Perth Longitudinal Study of Ageing Women. Archives of Gerontology and Geriatrics, -(-), -. https://doi.org/https://doi.org/10.1016/j.archger.2022.104911.
  • Radavelli Bagatini, S., Sim, M., Blekkenhorst, L., Bondonno, N., Bondonno, C., Woodman, R., Dickson, J., Harms, C., Magliano, D., Shaw, J., Daly, R., Hodgson, J., Lewis, J. (2022). Higher Consumption of Fruit and Vegetables Is Associated With Lower Worries, Tension and Lack of Joy Across the Lifespan. Frontiers in Nutrition, 9(2 May 2022), Article number 837066. https://doi.org/10.3389/fnut.2022.837066.
  • McKay, A., Sim, M., Moretti, D., Hall, R., Stellingwerff, T., Burden , R., Peeling, P. (2022). Methodological Considerations for Investigating Iron Status and Regulation in Exercise and Sport Science Studies. International Journal of Sport Nutrition and Exercise Metabolism, 32(5), 359–370. https://doi.org/10.1123/ijsnem.2021-0343.
  • Gebre, A., Sim, M., Dalla Via, J., Rodriguez, A., Hodgson, J., Bondonno, C., Thompson, PL., Prince, RL., Lewis, J. (2022). Measures of carotid atherosclerosis and fall-related hospitalization risk: The Perth Longitudinal Study of Ageing Women. Nutrition Metabolism and Cardiovascular Diseases, 2022(article in press), 1-31. https://doi.org/10.1016/j.numecd.2022.10.003.
  • McCaskie, C., Sim, M., Newton, R., Heasman, J., Rogalski, B., Hart, N. (2022). Characterising lower-body musculoskeletal morphology and whole-body composition of elite female and male Australian Football players. BMC Sports Science, Medicine and Rehabilitation, 14(1), Article number 168. https://doi.org/10.1186/s13102-022-00561-8.
  • Radavelli Bagatini, S., Gebre, A., Kennedy, M., Sim, M., Blekkenhorst, L., Bondonno, C., Jackson, B., Dimmock, J., Schlaich, MP., Hodgson, J., Lewis, J. (2022). Provision of non-invasive coronary and carotid vascular imaging results on changes in diet and physical activity in asymptomatic adults: A scoping review. Frontiers in Nutrition, 9(2022), Article Number 946378. https://doi.org/10.3389/fnut.2022.946378.
  • McCaskie, C., Sim, M., Newton, R., Heasman, J., Rogalski, B., Hart, N. (2022). Pre-season body composition has minimal influence on in-season match availability, and match performance in female Australian Football League (AFLW) players. Frontiers in Sports and Active Living, 4(26 October 2022), Article Number 963946. https://doi.org/10.3389/fspor.2022.963946.
  • Gebre, A., Prince, R., Schousboe, J., Kiel, D., Thompson, P., Zhu, K., Lim, W., Sim, M., Lewis, J. (2022). Calcaneal quantitative ultrasound is associated with all-cause and cardiovascular disease mortality independent of hip bone mineral density. Osteoporosis International, 2022(article in press), 1-11. https://doi.org/10.1007/s00198-022-06317-x.
  • Smith, C., Woessner, M., Sim, M., Levinger, I. (2022). Sarcopenia definition: does it really matter? Implications for resistance training?. Ageing Research Reviews, 78(June 2022), article number 101617. https://doi.org/10.1016/j.arr.2022.101617.
  • Sim, M., Dalla Via, J., Scott, D., Lim, W., Hodgson, J., Zhu, K., Daly, R., Duque, G., Prince, R., Lewis, J. (2022). Creatinine to cystatin C ratio, a biomarker of sarcopenia measures and falls risk in community-dwelling older women. Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 77(7), 1389-1397. https://doi.org/10.1093/gerona/glab369.
  • Radavelli Bagatini, S., Sim, M., Blekkenhorst, L., Bondonno, N., Bondonno, C., Woodman, R., Dickson, J., Magliano, DJ., Shaw, JE., Daly, RM., Hodgson, J., Lewis, J. (2022). Associations of specific types of fruit and vegetables with perceived stress in adults: The AusDiab study. European Journal of Nutrition, 61(9), 2929-2938. https://doi.org/10.1007/s00394-022-02848-5.
  • Zanker, J., Sim, M., Anderson, K., Balogun, S., Brennan-Olsen, S., Dent, E., Duque, G., Girgis, C., Grossmann, M., Hayes, A., Henwood, T., Hirani, V., Inderjeeth, C., Iuliano, S., Keogh, J., Lewis, J., Lynch, G., Pasco, J., Phu, S., Reijnierse, E., Russell, N., Vlietstra, L., Visvanathan, R., Walker, T., Waters, D., Yu, S., Maier, A., Daly, R., Scott, D. (2022). The Australian and New Zealand Society for Sarcopenia and Frailty Research (ANZSSFR) sarcopenia diagnosis and management task force: Findings from the consumer expert Delphi process. Australasian Journal on Ageing, 2022(Article in Press), TBD. https://doi.org/10.1111/ajag.13164.
  • Mavropalias, G., Sim, M., Taaffe, D., Galvao, D., Spry, N., Kraemer, W., Häkkinen, K., Newton, R. (2022). Exercise Medicine for Cancer Cachexia: Targeted Exercise To Counteract Mechanisms And Treatment Side-Effects. Journal of Cancer Research and Clinical Oncology, 148(2022), 1389–1406. https://doi.org/10.1007/s00432-022-03927-0.
  • Zengin , A., Shore-Lorenti , C., Sim, M., Maple-Brown, L., Brennan-Olsen, S., Lewis, J., Ockwell, J., Walker, T., Scott, D., Ebeling, P. (2022). Why Aboriginal and Torres Strait Islander Australians fall and fracture: the co-designed study of indigenous muscle and bone ageing (SIMBA) protocol. BMJ Open, 12(4), article number e056589. https://doi.org/10.1136/bmjopen-2021-056589.
  • Porter, T., Sim, M., Prince, R., Schousboe, JT., Bondonno, C., Lim, WH., Zhu, K., Kiel, DP., Hodgson, J., Laws, S., Lewis, J. (2022). Abdominal aortic calcification on lateral spine images captured during bone density testing and late-life dementia risk in older women: a prospective cohort study. The Lancet Regional Health - Western Pacific, 2022(Article in Press), 59p.
  • Raubenheimer, K., Liu, AH., Koch, H., Bosio, E., Bondonno, N., Matthews, V., Sim, M., Blekkenhorst, L., Woodman, R., Murray, K., Croft, K., Neubauer, O., Hodgson, J., Bondonno, C. (2022). Increased nitrate intake from beetroot juice does not alter soluble cellular adhesion molecules and circulating inflammatory cytokines in individuals with treated hypertension: a randomised, controlled trial. Food & Function, 13(23), 12353-12362. https://doi.org/10.1039/d2fo02403a.

Journal Articles

  • Blekkenhorst, L., Sim, M., Radavelli Bagatini, S., Bondonno, N., Bondonno, C., Devine, A., Schousboe, J., Lim, W., Kiel, D., Woodman, R., Hodgson, J., Prince, R., Lewis, J. (2021). Cruciferous vegetable intake is inversely associated with extensive abdominal aortic calcification in elderly women: a cross-sectional study. The British Journal of Nutrition: an international journal of nutritional science, 125(3), 337-345. https://doi.org/10.1017/S0007114520002706.
  • Tacey, A., Sim, M., Smith, C., Woessner , M., Byrnes , E., Lewis, J., Brennan-Speranza , T., Hodgson, J., Blekkenhorst, L., Levinger, I. (2021). Association between Circulating Osteocalcin and Cardiometabolic Risk Factors following a 4-Week Leafy Green Vitamin K-Rich Diet. Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics, 76(5), 361–367. https://doi.org/10.1159/000511660.
  • Smith, C., Lewis, J., Sim, M., Lim, W., Lim, E., Blekkenhorst, L., Brennan-Speranza , T., Adams, L., Byrnes, E., Duque, G., Levinger, I., Prince, R. (2021). Higher Undercarboxylated to Total Osteocalcin Ratio Is Associated With Reduced Physical Function and Increased 15‐Year Falls‐Related Hospitalizations: The Perth Longitudinal Study of Aging Women. Journal of Bone and Mineral Research, 36(3), 523-530. https://doi.org/10.1002/jbmr.4208.
  • Leow, K., Szulc, P., Schousboe, J., Kiel, D., Teixeira-Pinto, A., Shaikh, H., Sawang, M., Sim, M., Bondonno, N., Hodgson, J., Sharma, A., Thompson, P., Prince, R., Craig, J., Lim, W., Wong, G., Lewis, J. (2021). Prognostic value of abdominal aortic calcification: A systematic review and meta-analysis of observational studies. Journal of the American Heart Association, 10(2), Article number e017205. https://doi.org/10.1161/JAHA.120.017205.
  • Bellenge, J., Dalgaard, F., Murray, K., Connolly, E., Blekkenhorst, L., Bondonno, C., Lewis, J., Sim, M., Croft, K., Gislason , G., Torp-Pedersen, C., Tjønneland , A., Overvad , K., Hodgson, J., Schultz, C., Bondonno, N. (2021). Vitamin K Intake and Atherosclerotic Cardiovascular Disease in The Danish Diet Cancer and Health Study. Journal of the American Heart Association, 10(16), Article number e020551. https://doi.org/10.1161/JAHA.120.020551.
  • Sim, M., Zhu, K., Lewis, J., Hodgson, J., Prince, R. (2021). Association between vitamin D status and long-term falls-related hospitalization risk in older women. Journal of the American Geriatrics Society, 69(11), 3114-3123. https://doi.org/10.1111/jgs.17442.
  • Radavelli Bagatini, S., Blekkenhorst, L., Sim, M., Prince, R., Bondonno, N., Bondonno, C., Woodman, R., Anokye, R., Dimmock, J., Jackson, B., Costello, L., Devine, A., Stanley, M., Dickson, J., Magliano, D., Shaw, J., Daly, R., Hodgson, J., Lewis, J. (2021). Fruit and vegetable intake is inversely associated with perceived stress across the adult lifespan. Clinical Nutrition, 40(5), 2860-2867. https://doi.org/10.1016/j.clnu.2021.03.043.
  • Radavelli Bagatini, S., Anokye, R., Bondonno, N., Sim, M., Bondonno, C., Stanley, M., Harms, C., Woodman, R., Magliano, D., Shaw, J., Daly, R., Hodgson, J., Lewis, J., Blekkenhorst, L. (2021). Association of habitual intake of fruits and vegetables with depressive symptoms: the AusDiab study. European Journal of Nutrition, 60(7), 3743-3755. https://doi.org/10.1007/s00394-021-02532-0.
  • Gebre, A., Sim, M., Rodriguez, A., Hodgson, J., Blekkenhorst, L., Szulc, P., Bondonno, N., Zhu, K., Bondonno, C., Kiel, D., Schousboe, J., Prince, R., Lewis, J. (2021). Abdominal aortic calcification is associated with a higher risk of injurious fall-related hospitalizations in older Australian women. Atherosclerosis, 328(July 2021), 153-159. https://doi.org/10.1016/j.atherosclerosis.2021.05.003.
  • Teh , R., Prince, R., Sim, M., Schousboe , J., Raymond, W., Szulc, P., Lim, W., Hodgson, J., Zhu, K., Kiel, D., Schultz, C., Thompson, P., Lewis, J. (2021). Abdominal aortic calcification, cardiac troponin I and atherosclerotic vascular disease mortality in older women. Heart, 2021(Article in press), 1-7 pp. https://doi.org/10.1136/heartjnl-2021-319879.
  • McCaskie, C., Sim, M., Newton, R., Hart, N. (2021). Lower-limb injury in elite Australian football: a narrative review of kinanthropometric and physical risk factors. Physical Therapy in Sport, 52(November 2021), 69-80. https://doi.org/10.1016/j.ptsp.2021.08.006.
  • Palmer, C., Koch, H., Shinde, S., Blekkenhorst, L., Lewis, J., Croft, K., Hodgson, J., Sim, M. (2021). Development of a Vitamin K database for commercially available food in Australia. Frontiers in Nutrition, 8(December 2021), Article number 753059. https://doi.org/10.3389/fnut.2021.753059.
  • Connolly, E., Sim, M., Travica, N., Marx, W., Beasy, G., Lynch, G., Bondonno, C., Lewis, J., Hodgson, J., Blekkenhorst, L. (2021). Glucosinolates from cruciferous vegetables and their potential role in chronic disease: investigating the preclinical and clinical evidence. Frontiers in Pharmacology, 12(Oct 2021), Article number 767975. https://doi.org/10.3389/fphar.2021.767975.
  • Bondonno, N., Davey, R., Murray, K., Radavelli Bagatini, S., Bondonno, C., Blekkenhorst, L., Sim, M., Magliano, D., Daly, R., Shaw, J., Lewis, J., Hodgson, J. (2021). Associations between fruit intake and risk of diabetes in the AusDiab cohort. The Journal of Clinical Endocrinology and Metabolism, 106(10), E4097-E4108. https://doi.org/10.1210/clinem/dgab335.
  • Palmer, C., Bellinge, J., Dalgaard, F., Sim, M., Murray, K., Connolly, E., Blekkenhorst, L., Bondonno, C., Croft, K., Gislason, G., Tjønneland, A., Overvad, K., Schultz, C., Lewis, J., Hodgson, J., Bondonno, N. (2021). Association between vitamin K1 intake and mortality in the Danish Diet, Cancer, and Health cohort. European Journal of Epidemiology, 36(10), 1005–1014. https://doi.org/10.1007/s10654-021-00806-9.
  • Sim, M., Blekkenhorst, L., Bondonno, N., Radavelli Bagatini, S., Peeling, P., Bondonno, C., Magliano, D., Shaw, J., Woodman , R., Murray, K., Lewis, J., Daly, R., Hodgson, J. (2021). Dietary nitrate intake is positively associated with muscle function in men and women independent of physical activity levels. The Journal of Nutrition, 151(5), 1222 - 1230. https://doi.org/10.1093/jn/nxaa415.
  • Rees, J., Radavelli Bagatini, S., Lo, J., Hodgson, J., Christophersen, C., Daly, R., Magliano, D., Shaw, J., Sim, M., Bondonno, C., Blekkenhorst, L., Dickson, J., Lewis, J., Devine, A. (2021). Association between Fruit and Vegetable Intakes and Mental Health in the Australian Diabetes Obesity and Lifestyle Cohort. Nutrients, 13(5), Article number 1447. https://doi.org/10.3390/nu13051447.

Journal Articles

  • Sim, M., Lewis, J., Prince, R., Levinger, I., Brennan-Speranza, T., Palmer, C., Bondonno, C., Bondonno, N., Devine, A., Ward, N., Byrnes, E., Schultz, C., Woodman, R., Croft, K., Hodgson, J., Blekkenhorst, L. (2020). The effects of vitamin K-rich green leafy vegetables on bone metabolism: a 4-week randomised controlled trial in middle-aged and older individuals. Bone Reports, 12(June 2020), Article number 100274. https://doi.org/10.1016/j.bonr.2020.100274.
  • Radavelli Bagatini, S., Bondonno, C., Sim, M., Blekkenhorst, L., Anokye, R., Connolly, E., Bondonno, N., Schoesboe, J., Woodman, R., Zhu , K., Szulc, P., Jackson, B., Dimmock, J., Schlaich, M., Cox, K., Kiel, D., Lim, W., Stanley, M., Devine, A., Thompson, P., Gianoudis, J., De Ross, B., Daly, R., Lewis, J., Hodgson, J. (2020). Modification Of Diet, Exercise and Lifestyle (MODEL) study: a randomised controlled trial protocol. BMJ Open, 10(11), Article number 036366. https://doi.org/10.1136/bmjopen-2019-036366.
  • Anokye, R., Radavelli Bagatini, S., Bondonno, C., Sim, M., Blekkenhorst, L., Connolly, E., Bondonno, N., Schousboe, J., Woodman, R., Zhu, K., Szulc, P., Jackson, B., Dimmock, J., Schlaich, M., Cox, K., Kiel, D., Lim, W., Devine, A., Thompson, P., Gianoudis, J., De Ross, B., Daly, R., Hodgson, J., Lewis, J., Stanley, M. (2020). Implementation, mechanisms of impact and key contextual factors involved in outcomes of the Modification of Diet, Exercise and Lifestyle (MODEL) randomised controlled trial in Australian adults: Protocol for a mixed-method process evaluation. BMJ Open, 10(11), Article number 036395. https://doi.org/10.1136/bmjopen-2019-036395.
  • McCormick, R., Dryer, A., Dawson, B., Sim, M., Lester, L., Goodman, C., Peeling, P. (2020). The effectiveness of daily and alternate day oral iron supplementation in athletes with sub-optimal iron status (Part 2). International Journal of Sport Nutrition and Exercise Metabolism, 30(3), 191-196. https://doi.org/10.1123/ijsnem.2019-0310.
  • Palmer, C., Blekkenhorst, L., Lewis, J., Ward, N., Schultz, CJ., Hodgson, J., Croft, K., Sim, M. (2020). Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review. Food and Function, 11(4), 2826-2837. https://doi.org/10.1039/c9fo02321f.
  • Blekkenhorst, L., Lewis, J., Bondonno, C., Sim, M., Devine, A., Zhu, K., Lim, WH., Woodman, RJ., Beilin, LJ., Thompson, PL., Prince, RL., Hodgson, J. (2020). Vegetable diversity in relation with subclinical atherosclerosis and 15-year atherosclerotic vascular disease deaths in older adult women. European Journal of Nutrition, 59(1), 217-230. https://doi.org/10.1007/s00394-019-01902-z.
  • Connolly, E., Bondonno, C., Sim, M., Radavelli Bagatini, S., Croft, K., Boyce, M., James, A., Clark, K., Anokye, R., Bondonno, N., Woodman, R., Devine, A., Gan, SK., Schultz, C., Mithen, R., Lewis, J., Hodgson, J., Blekkenhorst, L. (2020). A randomised controlled crossover trial investigating the short-term effects of different types of vegetables on vascular and metabolic function in middle-aged and older adults with mildly elevated blood pressure: the VEgetableS for vaScular hEaLth (VESSEL) study protocol. Nutrition Journal, 19(1), Article number 41. https://doi.org/10.1186/s12937-020-00559-3.
  • Hill, C., Blekkenhorst, L., Radavelli Bagatini, S., Sim, M., Woodman, R., Devine, A., Shaw, J., Hodgson, J., Daly, R., Lewis, J. (2020). Fruit and Vegetable Knowledge and Intake within an Australian Population: The AusDiab Study. Nutrients, 12(12), Article number 3628. https://doi.org/10.3390/nu12123628.
  • McCormick, R., Sim, M., Dawson, B., Peeling, P. (2020). Refining Treatment Strategies for Iron Deficient Athletes. Sports Medicine, 50(12), 2111-2123. https://doi.org/10.1007/s40279-020-01360-2.
  • Halley, S., Peeling, P., Brown , H., Sim, M., Mallabone, J., Dawson, B., Binnie, M. (2020). Repeat Application of Ischemic Preconditioning Improves Maximal 1,000-m Kayak Ergometer Performance in a Simulated Competition Format. Journal of Strength and Conditioning Research, 2020(Article in press), 1-7. https://doi.org/10.1519/JSC.0000000000003748.
  • McCormick, R., Dawson, B., Sim, M., Lester, L., Goodman, C., Peeling, P. (2020). The Effectiveness of Transdermal Iron Patches in Athletes with Sub-Optimal Iron Status (Part 1). International Journal of Sport Nutrition and Exercise Metabolism, 30(3), 185-190. https://doi.org/10.1123/ijsnem.2019-0309.
  • McKay, A., Peeling, P., Binnie, M., Goods , P., Sim, M., Cross, R., Siegler, J. (2020). Topical Sodium Bicarbonate: No Improvement in Blood Buffering Capacity or Exercise Performance. International Journal of Sports Physiology and Performance, 15(7), 1005–1011. https://doi.org/10.1123/ijspp.2019-0345.

Journal Articles

  • McCaskie, C., Young, W., Fahrner, B., Sim, M. (2019). Association between preseason training and performance in elite Australian football. International Journal of Sports Physiology and Performance, 14(1), 68-75. https://doi.org/10.1123/ijspp.2018-0076.
  • Rodriguez, A., Leow, K., Szulc, P., Scott, D., Ebeling, P., Sim, M., Wong, G., Lim, W., Schousboe, JT., Kiel, D., Prince, R., Lewis, J. (2019). Abdominal aortic calcification, bone mineral density and fractures: a systematic review and meta-analysis protocol. BMJ Open, 9(4), Article number e026232. https://doi.org/10.1136/bmjopen-2018-026232.
  • Zhu, K., Lewis, J., Sim, M., Prince, R. (2019). Low vitamin D status is associated with impaired bone quality and increased risk of fracture-related hospitalization in older Australian women. Journal of Bone and Mineral Research, 34(11), 2019-2027. https://doi.org/10.1002/jbmr.3818.
  • Sim, M., Lewis, J., Blekkenhorst, L., Bondonno, C., Devine, A., Zhu, K., Peeling, P., Prince, R., Hodgson, J. (2019). Dietary nitrate intake is associated with muscle function in older women. Journal of Cachexia, Sarcopenia and Muscle, 10(3), 601-610. https://doi.org/10.1002/jcsm.12413.
  • Lewis, J., Brennan-Speranza, T., Levinger, I., Byrnes, E., Lim, E., Blekkenhorst, L., Sim, M., Hodgson, J., Zhu, K., Lim, W., Adams, L., Prince, R. (2019). Effects of calcium supplementation on circulating osteocalcin and glycated hemoglobin in older women. Osteoporosis International, 30(10), 2065-2072. https://doi.org/10.1007/s00198-019-05087-3.
  • Zanker, J., Scott , D., Reijnierse , E., Brennan-Olsen , S., Daly , R., Girgis , C., Grossmann , M., Hayes , A., Henwood , T., Hirani , V., Inderjeeth , C., Iuliano, S., Keogh, J., Lewis, J., Maier , A., Pasco, J., Phu, S., Sanders, K., Sim, M., Visvanathan , R., Waters , D., Yu , S., Duque , G. (2019). Establishing an Operational Definition of Sarcopenia in Australia and New Zealand: Delphi Method Based Consensus Statement. Journal of Nutrition, Health and Aging, 23(1), 105-110. https://doi.org/10.1007/s12603-018-1113-6.
  • Lewis, J., Eggermont, C., Schousboe, J., Lim, W., Wong, G., Khoo, B., Sim, M., Yu, M., Ueland, T., Bollerslev , J., Hodgson, J., Zhu, K., Wilson, K., Kiel, D., Prince, R. (2019). Association between abdominal aortic calcification, bone mineral density and fracture in older women. Journal of Bone and Mineral Research, 34(11), 2052-2060. https://doi.org/10.1002/jbmr.3830.
  • Lewis, J., Sim, M., Daly, R. (2019). The Vitamin D and Calcium Controversy: An Update. Current Opinion in Rheumatology, 31(2), 91-97. https://doi.org/10.1097/BOR.0000000000000584.
  • Sim, M., Prince, R., Scott, D., Daly, R., Duque, G., Inderjeeth, C., Kun, Z., Woodman, R., Hodgson, J., Lewis, J. (2019). Utility of four sarcopenia criteria for the prediction of falls-related hospitalization in older Australian women. Osteoporosis International, 30(1), 167-176. https://doi.org/10.1007/s00198-018-4755-7.
  • Sim, M., Prince, R., Scott, D., Daly, R., Duque, G., Charles, I., Kun, Z., Richard, W., Hodgson, J., Lewis, J. (2019). Sarcopenia Definitions and Their Associations With Mortality in Older Australian Women. Journal of the American Medical Directors Association (JAMDA): long-term care: management, applied research and clinical issues, 20(1), 76-82.e2. https://doi.org/10.1016/j.jamda.2018.10.016.
  • Sim, M., Garvican-Lewis, L., Cox, G., Govus, A., McKay, A., Stellingwerff, T., Peeling, P. (2019). Iron considerations for the athlete: A narrative review. European Journal of Applied Physiology, 119(7), 1463-1478. https://doi.org/10.1007/s00421-019-04157-y.
  • McCormick, R., Moretti, D., McKay , A., Laarakkers , C., Van Swelm, R., Trinder , D., Cox, G., Zimmerman , M., Sim, M., Goodman , C., Dawson, B., Peeling, P. (2019). The impact of morning versus afternoon exercise on iron absorption in athletes. Medicine and Science in Sports and Exercise, 51(10), 2147-2155. https://doi.org/10.1249/MSS.0000000000002026.

Journal Articles

  • Blekkenhorst, L., Sim, M., Bondonno, C., Bondonno, N., Ward, N., Prince, R., Devine, A., Lewis, J., Hodgson, J. (2018). Cardiovascular Health Benefits of Specific Vegetable Types: A Narrative Review. Nutrients, 10(5), Article no.595. https://doi.org/10.3390/nu10050595.
  • Terziottia, P., Sim, M., Polglaze, T. (2018). A comparison of displacement and energetic variables between three team sport GPS devices. International Journal of Performance Analysis in Sport, 18(5), 823-834. https://doi.org/10.1080/24748668.2018.1525650.
  • Sim, M., Blekkenhorst, L., Lewis, J., Bondonno, C., Devine, A., Zhu, K., Woodman, R., Prince, R., Hodgson, J. (2018). Vegetable Diversity, Injurious Falls, and Fracture Risk in Older Women: A Prospective Cohort Study. Nutrients, 10(8), Article no.1081. https://doi.org/10.3390/nu10081081.
  • Peeling, P., Binnie, M., Goods, P., Sim, M., Burke, L. (2018). Evidence-Based Supplements for the Enhancement of Athletic Performance. International Journal of Sport Nutrition and Exercise Metabolism, 28(2), 178-187. https://doi.org/10.1123/ijsnem.2017-0343.
  • Sim, M., Blekkenhorst, L., Lewis, J., Bondonno, C., Devine, A., Zhu, K., Woodman, R., Prince, R., Hodgson, J. (2018). Vegetable and fruit intake and injurious falls risk in older women: a prospective cohort study. The British Journal of Nutrition: an international journal of nutritional science, 120(8), 925-934. https://doi.org/10.1017/S0007114518002155.

Journal Articles

  • Sim, M., Dawson, B., Landers, G., Swinkels, D., Wiegerinck, E., Yeap, B., Trinder, D., Peeling, P. (2017). Interleukin-6 and Hepcidin Levels during Hormone-Deplete and Hormone-Replete Phases of an Oral Contraceptive Cycle: A Pilot Study. Annals of Nutrition and Metabolism: European journal of nutrition, metabolic diseases and dietetics, 70(2), 100-105. https://doi.org/10.1159/000465530.
  • Brown, H., Dawson, B., Binnie, M., Pinnington, H., Sim, M., Clemons, T., Peeling, P. (2017). Sand training: Exercise-induced muscle damage and inflammatory responses to matched-intensity exercise. European Journal of Sport Science, 17(6), 741-747. https://doi.org/10.1080/17461391.2017.1304998.

Journal Articles

  • McCormick, R., Peeling, P., Binnie, M., Dawson, B., Sim, M. (2016). Effect of tart cherry juice on recovery and next day performance in well-trained Water Polo players. Journal of the International Society of Sports Nutrition, 13(1), Article number 41. https://doi.org/10.1186/s12970-016-0151-x.
  • Badenhorst, C., Dawson, B., Cox, G., Sim, M., Laarakkers, C., Swinkels, D., Peeling, P. (2016). Seven days of high carbohydrate ingestion does not attenuate post‑exercise IL‑6 and hepcidin levels. European Journal of Applied Physiology, 116(9), 1715-1724. https://doi.org/10.1007/s00421-016-3426-7.

Journal Articles

  • Sim, M., Dawson, B., Landers, G., Swinkels, D., Tjalsma, H., Yeap, B., Trinder, D., Peeling, P. (2015). Oral contraception does not alter typical post-exercise interleukin-6 and hepcidin levels in females. Journal of Science and Medicine in Sport, 18(1), 8-12. https://doi.org/10.1016/j.jsams.2013.11.008.

Journal Articles

  • Badenhorst, C., Dawson, B., Goodman, C., Sim, M., Cox, G., Gore, C., Tjalsma, H., Swinkels, D., Peeling, P. (2014). Influence of post-exercise hypoxic exposure on hepcidin response in athletes. European Journal of Applied Physiology, 114(5), 951-959. https://doi.org/10.1007/s00421-014-2829-6.
  • Peeling, P., Sim, M., Badenhorst, CE., Dawson, B., Govus, A., Abbiss, C., Swinkels, DW., Trinder, D. (2014). Iron status and the acute post-exercise hepcidin response in athletes. PLoS One, 9(3), Article No. e93002. https://doi.org/10.1371/journal.pone.0093002.
  • Sim, M., Dawson, B., Landers, G., Trinder, D., Peeling, P. (2014). Iron regulation in athletes: Exploring the menstrual cycle and effects of different exercise modalities on hepcidin production. International Journal of Sport Nutrition and Exercise Metabolism, 24(2), 177-187. https://doi.org/10.1123/ijsnem.2013-0067.
  • Sim, M., Dawson, B., Landers, G., Swinkels, D., Tjalsma, H., Wiegerinck, E., Trinder, D., Peeling, P. (2014). A seven day running training period increases basal urinary hepcidin levels as compared to cycling. Journal of the International Society of Sports Nutrition, 11(1), Article number 14. https://doi.org/10.1186/1550-2783-11-14.

Journal Articles

  • Sim, M., Dawson, B., Landers, G., Swinkels, D., Tjalsma, H., Trinder, D., Peeling, P. (2013). Effect of exercise modality and intensity on postexercise interlukin-6 and hepcidin levels. International Journal of Sport Nutrition and Exercise Metabolism, 23(2), 178-186.
  • Spence, A., Sim, M., Landers, G., Peeling, P. (2013). A comparison of caffeine versus pseudoephedrine on cycling time-trial performance. International Journal of Sport Nutrition and Exercise Metabolism, 23(5), 507-512.

Book Chapters

Journal Articles

  • Peeling, P., Fulton, S., Sim, M., White, J. (2012). Recovery effects of hyperoxic gas inhalation or contrast water immersion on the postexercise cytokine response, perceptual recovery, and next day exercise performance. Journal of Strength and Conditioning Research, 26(4), 968-975.
  • Sim, M., Dawson, B., Landers, G., Wiegerinck, E., Swinkels, D., Townsend, M., Trinder, D., Peeling, P. (2012). The effects of carbohydrate ingestion during endurance running on post-exercise inflammation and hepcidin levels. European Journal of Applied Physiology, 112(5), 1889-1898. https://doi.org/10.1007/s00421-011-2156-0.

Research Projects

  • Getting to the heart of healthy aging: a behaviour change program to promote dietary pattern changes, National Health and Medical Research Council, MRFF - Dementia, Ageing and Aged Care Mission, 2022 ‑ 2026, $626,963.
  • Investigating genetic and lifestyle determinants of abdominal aortic calcification, and their relationship with cardiovascular disease, National Health and Medical Research Council, MRFF - Cardiovascular Health Mission, 2023 ‑ 2026, $1,202,213.
  • Mindful mouthfuls: Developing healthy eating behaviours from infancy, Royal Perth Hospital Medical Research Foundation, Springboard Grants, 2023 ‑ 2025, $28,050.
  • Happy Kids Through Connected Parenting, Channel 7 Telethon Trust, Grant, 2023 ‑ 2024, $118,558.
  • Career Advancement Fellowship 2020, Royal Perth Hospital Medical Research Foundation, Career Advancement Fellowship, 2021 ‑ 2024, $145,865.
  • Preventing falls in older Australians: an appetite for change, Department of Health WA, WA Near-miss Awards: Emerging Leaders Program, 2022 ‑ 2024, $260,296.
  • A novel machine-learning approach to reduce falls in older community-dwelling Australians, Department of Health WA, WA Near-miss Awards: Ideas , 2022 ‑ 2023, $100,000.
  • Reducing falls and their burden in older Australians, Department of Health WA, Near Miss Merit Awards, 2021 ‑ 2022, $74,000.
  • Can the short-term consumption of vitamin K rich vegetables improve markers of musculoskeletal health?, Edith Cowan University, ECU Early Career Researcher Grant - 2019, 2019 ‑ 2020, $19,474.
  • Developing a national database for vitamin K1 and K2 content in food, Royal Perth Hospital Medical Research Foundation, Seeding Grant, 2018 ‑ 2020, $17,331.

Research Student Supervision

Principal Supervisor

  • Doctor of Philosophy, Discerning an estimate of dietary vitamin K requirements to improve cardiovascular related health outcomes in Australia

Co-principal Supervisor

  • Doctor of Philosophy, An examination of kinanthropometric and physical injury risk factors in elite Australian Football
  • Doctor of Philosophy, Cardiovascular Disease, Musculoskeletal Health and Falls: Exploring the Nexus

Principal Supervisor

  • Doctor of Philosophy, Towards an understanding of the interaction between exercise and dietary iron absorption: Refining treatment strategies for iron deficit athletes.

Associate Supervisor

  • Doctor of Philosophy, Diet, Cardiovascular Disease, and Mental Health
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