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Mr Ian Martins is a Research Fellow in the School of Medical and Health Sciences.
Doctor of Philosophy (Biochemistry), The University of Western Australia, 1987.
Recent Research Grants
Short chain fatty acids are a useful therapy for the treatment of Alzheimer's Disease. , Hollywood Private Hospital Research Foundation, Grant,
2013 - 2016, $20,000.
Use of coconut oil as a novel neuro protective agent for Alzheimer’s disease, Edith Cowan University, School of Medical and Health Sciences Research Grant Scheme 2016,
The Effect of Human apoE Isoforms and apoE Receptors on the Clearance of Oligomeric A 42 by Hepatocytes In Vitro, National Health and Medical Research Council, Grant,
2010 - 2013, $409,650.
Enhancing Peripheral Clearance of Beta Amyloid as a Treatment of Alzheimer's Disease, National Health and Medical Research Council, Grant,
2010 - 2013, $529,125.
Neon Transfection System and Biomedical Research Grade -30oC Freezer for Alzheimer’s and Melanoma Research, National Health and Medical Research Council, Equipment Grant 2011,
2011 - 2012, $10,927.
Investigating beta amyloid clearance in vivo, Centre of Excellence for Alzheimers Disease Research and Care, Fellowship,
2006 - 2009, $207,655.
-30C Freezer for Increased Tissue/Blood Storage Capacity in the Alzheimer's Disease Research Laboratory, Edith Cowan University, Grant,
2007 - 2008, $12,266.
Cholesterol, high fat diets, exercise and cholesterol lowering drugs on beta-amyloid clearance and deposition in brains on Alzheimer's disease transgenic mice, Hollywood Private Hospital, Grant,
2006 - 2007, $9,455.
Molecular & neuropsychological predictive markers of cognitive decline, National Health and Medical Research Council, Grant,
2005 - 2007, $423,750.
Recent Publications (within the last five years)
Hone, E., Lim, F., Martins, I., (2019), Fat and Lipid Metabolism and the Involvement of Apolipoprotein E in Alzheimer's Disease. Neurodegeneration and Alzheimer's Disease The role of diabetes, Genetics, Hormones and Lifestyle, 189-230, United Kingdom , John Wiley & Sons, DOI: 10.1002/9781119356752.ch7.
Martins, R., Villemagne, V., Sohrabi, H., Chatterjee, P., Shah, T., Verdile, G., Fraser, P., Taddei, K., Gupta, V., Rainey-Smith, S., Hone, E., Pedrini, S., Lim, F., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K., Fuller, S., Brown, B., Kirby, S., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S., Barron, A., Goozee, K., Wahjoepramono, EJ., Asih, P., Doecke, J., Salvado, O., Bush, A., Rowe, C., Gandy, S., Masters, C., (2018), Alzheimer’s Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies—Gains from AIBL and DIAN Cohort Studies. Journal of Alzheimer's Disease, 62(3), 965-992, Netherlands, IOS Press, DOI: 10.3233/JAD-171145.
Bates, K., Sohrabi, H., Rainey-Smith, S., Weinborn, M., Bucks, R., Rodrigues, M., Beilby, J., Howard, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, L., Gandy, S., Martins, R., (2017), Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women. International Journal of Neuroscience, 127(3), 243-252, Taylor and Francis Ltd, DOI: 10.1080/00207454.2016.1182527.
Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, Frontiers Research Foundation, DOI: 10.3389/fnagi.2015.00016.
Fernando, B., Martins, I., Goozee, K., Brennan, C., Jayasena, V., Martins, R., (2015), The role of dietary coconut for the prevention and treatment of Alzheimer's disease: potential mechanisms of action. The British Journal of Nutrition, 114(1), 1-14, Cambridge, United Kingdom, Cambridge University Press, DOI: 10.1017/S0007114515001452.
Xu, H., Gupta, V., Martins, I., Martins, R., Fowler, CJ., Bush, AI., Finkelstein, DI., Adlard, PA., (2015), Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way. Neurobiology of Disease, 81(September 2015), 38-48, Elsevier, DOI: 10.1016/j.nbd.2015.06.016.
Research Student Supervision
Doctor of Philosophy, Identification of plasma lipid biomarkers in alzheimer's disease.