Mr Ian Martins is a Research Fellow in the School of Medical and Health Sciences.
Doctor of Philosophy (Biochemistry), The University of Western Australia, 1987.
Recent Research Grants
Short chain fatty acids are a useful therapy for the treatment of Alzheimer's Disease. , Hollywood Private Hospital Research Foundation, Grant,
2013 - 2016, $20,000.
Use of coconut oil as a novel neuro protective agent for Alzheimer’s disease, Edith Cowan University, School of Medical and Health Sciences Research Grant Scheme 2016,
The Effect of Human apoE Isoforms and apoE Receptors on the Clearance of Oligomeric A 42 by Hepatocytes In Vitro, National Health and Medical Research Council, Grant,
2010 - 2013, $409,650.
Enhancing Peripheral Clearance of Beta Amyloid as a Treatment of Alzheimer's Disease, National Health and Medical Research Council, Grant,
2010 - 2013, $529,125.
Neon Transfection System and Biomedical Research Grade -30oC Freezer for Alzheimer’s and Melanoma Research, National Health and Medical Research Council, Equipment Grant 2011,
2011 - 2012, $10,927.
Investigating beta amyloid clearance in vivo, Centre of Excellence for Alzheimers Disease Research and Care, Fellowship,
2006 - 2009, $207,655.
-30C Freezer for Increased Tissue/Blood Storage Capacity in the Alzheimer's Disease Research Laboratory, Edith Cowan University, Grant,
2007 - 2008, $12,266.
Cholesterol, high fat diets, exercise and cholesterol lowering drugs on beta-amyloid clearance and deposition in brains on Alzheimer's disease transgenic mice, Hollywood Private Hospital, Grant,
2006 - 2007, $9,455.
Molecular & neuropsychological predictive markers of cognitive decline, National Health and Medical Research Council, Grant,
2005 - 2007, $423,750.
Recent Publications (within the last five years)
Martins, I., (2015), Nutrition increases Survival and Reverses NAFLD and Alzheimer's disease., 168, Germany, Lambert Academic Publishing.
Martins, I., (2015), Nutritional diets accelerate amyloid beta metabolism and prevent the induction of chronic diseases and Alzheimer’s disease. Photon ebooks UBN: 015-A94510112017, 48, online, Photon.
Martins, I., (2013), Appetite dysregulation and Obesity in Western Countries., 88, Germany, Lambert Academic Publishing.
Martins, I., (2015), Nutritional and Genotoxic Stress Contributes to Diabetes and Neurodegenerative Diseases such as Parkinson's and Alzheimer's Diseases. Frontiers in Clinical Drug Research -CNS and Neurological Disorders, 3(7), 158-192, Bentham eBooks, Bentham Science Publishers, DOI: 10.2174/97816080592631140301.
Bates, K., Sohrabi, H., Rainey-Smith, S., Weinborn, M., Bucks, R., Rodrigues, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, L., Gandy, S., (2017), Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women. International Journal of Neuroscience, 127(3), 243-252, Taylor and Francis Ltd, DOI: 10.1080/00207454.2016.1182527.
Martins, I., (2016), Food quality induces a miscible disease with relevance to Alzheimer’s disease and Neurological diseases. Journal of Food Research, 5(6), 45-52, Canada, Canadian Center of Science and Education, DOI: 10.5539/ jfr. v5n6p 45.
Martins, I., (2016), Food Intake and Caffeine Determine Amyloid Beta Metabolism with Relevance to Mitophagy in Brain Aging and Chronic Disease. European Journal of Food Science and Technology, 4(5), 11-17, European Center for Research Training and Development.
Martins, I., (2016), Type 3 diabetes with links to NAFLD and other chronic diseases in the Western World. International Journal of Diabetes and Metabolic disorders, 1(1), 1-5, USA, Opast online publishing.
Martins, I., (2016), Bacterial Lipopolysaccharides Change Membrane Fluidity with Relevance to Phospholipid and Amyloid Beta Dynamics in Alzheimer’s Disease. Journal of Microbial Biochemical Technology, 8(4), 322-324, USA, OMICS publishing, DOI: 10.4172/1948-5948.1000304.
Martins, I., (2016), Early diagnosis of neuron mitochondrial dysfunction may reverse global metabolic and neurodegenerative disease. Global Journal of Medical Research, 16(2), 1-8, Global Academic Research Journals.
Martins, I., (2016), Appetite Control with Relevance to Mitochondrial Biogenesis and Activation of Post- Prandial Lipid Metabolism in Obesity Linked Diabetes. Annals of Obesity and Disorders, 1(3), 1-3, USA, Austin Publishing.
Martins, I., (2016), The Role of Clinical Proteomics, Lipidomics, and Genomics in the Diagnosis of Alzheimer’s Disease. Proteomes, 4(14), 1-19, Switzerland, MDPI, DOI: 10.3390/proteomes4020014.
Martins, I., (2016), Magnesium Therapy Prevents Senescence with the Reversal of Diabetes and Alzheimer’s Disease. Health, 8(2016), 694-710, United States of America, Scientific Research Publishing, DOI: 10.4236/health.2016.87073.
Martins, I., (2016), Diet and Nutrition Reverse Type 3 Diabetes and Accelerated Aging Linked to Global Chronic Diseases. Journal of Diabetes Research and Therapy, 2(2), 1-6, Germany, SciForschen, DOI: 10.16966/2380-5544.117.
Martins, I., (2016), Anti-Aging Genes Improve Appetite Regulation and Reverse Cell Senescence and Apoptosis in Global Populations. Advances in Aging Research, 5(2016), 9-26, United States of America, Scientific Research Publishing, DOI: 10.4236/aar.2016.51002.
Xu, H., Gupta, V., Martins, I., Martins, R., Fowler, CJ., Bush, AI., Finkelstein, DI., Adlard, PA., (2015), Zinc affects the proteolytic stability of Apolipoprotein E in an isoform-dependent way. Neurobiology of Disease, 81(September 2015), 38-48, Elsevier, DOI: 10.1016/j.nbd.2015.06.016.
Martins, I., (2015), Overnutrition determines LPS regulation of mycotoxin induced neurotoxicity in neurodegenerative diseases. International Journal of Molecular Sciences, 16(12), 29554-29573, Basel, Switzerland, MDPI AG, DOI: 10.3390/ijms161226190.
Martins, I., (2015), Diabetes and organ dysfunction in the developing and developed world. Global Journal of Medical Research, 15(1), 1-6, United States of America, Global Journals Inc..
Martins, I., (2015), Unhealthy nutrigenomic diets accelerate NAFLD and adiposity in global communities. Journal of Molecular and Genetic Medicine: an international journal of biomedical research, 9(1), 1-11, United States of America, Omics Publishing Group, DOI: 10.4172/1747-0862.1000162.
Fernando, B., Martins, I., Goozee, K., Brennan, C., Jayasena, V., Martins, R., (2015), The role of dietary coconut for the prevention and treatment of Alzheimer's disease: potential mechanisms of action. The British Journal of Nutrition, 114(1), 1-14, Cambridge, United Kingdom, Cambridge University Press, DOI: 10.1017/S0007114515001452.
Martins, I., (2015), Diabetes and cholesterol dyshomeostasis involve abnormal α-synuclein and amyloid beta transport in neurodegenerative diseases. Austin Alzheimer's and Parkinsons Disease, 2(1), 1-8, United States of America, Austin Publishing Group.
Martins, I., (2015), Unhealthy diets determine benign or toxic amyloid beta states and promote brain amyloid beta aggregation. Austin Journal of Clinical Neurology, 2(7), 1-6, United States of America, Austin Publishing Group.
Sohrabi, H., Bates, K., Weinborn, M., Bucks, R., Rainey-Smith, S., Rodrigues, M., Bird, S., Brown, B., Beilby, J., Howard, M., Criddle, A., Wraith, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S., Mehta, P., Foster, J., Martins, I., Lautenschlager, N., Mastaglia, F., Laws, S., Martins, R., (2015), Bone mineral density, adiposity, and cognitive functions. Frontiers in Aging Neuroscience, 7(FEB), Article no. 16, Lausanne, Switzerland, Frontiers Research Foundation, DOI: 10.3389/fnagi.2015.00016.
Martins, I., (2015), LPS regulates apolipoprotein E and Aβ interactions with effects on acute phase proteins and amyloidosis. Advances in Aging Research, 4(2015), 69-77, Scientific Research Publishing, DOI: 10.4236/aar.2015.42009.
Lim, F., Martins, I., Martins, R., (2014), The Involvement of Lipids in Alzheimer's Disease. Journal of Genetics and Genomics, 41(5), 261-274, Elsevier, DOI: 10.1016/j.jgg.2014.04.003.
Martins, I., (2014), The Global Obesity Epidemic is Related to Stroke, Dementia and Alzheimer’s disease. JSM Alzheimer’s Disease and Related Dementia, 1(2), 1010-1018, USA.
Martins, I., (2014), Induction of NAFLD with Increased Risk of Obesity and Chronic Diseases in Developed Countries. Open Journal of Endocrine and Metabolic Diseases, 2014(4), 90-110, United States of America, Scientific Research Publishing, Inc., DOI: 10.4236/ojemd.2014.44011.
Martins, I., Fernando, B., (2014), High Fibre Diets and Alzheimer’s Disease. Food and Nutrition Sciences, 5(4), 410-424, United States of America.
Martins, I., Gupta, V., Wilson, A., Fuller, SJ., Martins, R., (2014), Interactions Between Apo E and Amyloid Beta and their Relationship to Nutriproteomics and Neurodegeneration. Current Proteomics: the journal for current and in-depth reviews on proteomics, 11(3), 171-183, Netherlands, Bentham Science Publishers.
Martins, I., Creegan, R., (2014), Links between Insulin Resistance, Lipoprotein Metabolism and Amyloidosis in Alzheimer’s Disease. Health, 6(10), 1549-1579, USA, DOI: 10.4236/health.2014.612190.
Martins, I., Creegan, R., Lim, F., Martins, R., (2013), Molecular insights into appetite control and neuroendocrine disease as risk factors for chronic diseases in Western countries. Open Journal of Endocrine and Metabolic Diseases, 3(5A), 11-33, United States of America, Scientific Research, DOI: 10.4236/ojemd.2013.35A002.
Martins, I., (2013), Increased Risk for Obesity and Diabetes with Neurodegeneration in Developing Countries. Journal of Molecular and Genetic Medicine: an international journal of biomedical research, S1(001), 8p., United States of America, OMICS, DOI: 10.4172/1747-0862.S1-001.
Lim, F., Lam, SM., Shui, G., Mondal, A., Ong, D., Duan, X., Creegan, R., Martins, I., Sharman, M., Taddei, K., Verdile, G., Wenk, M., Martins, R., (2013), Effects of a high-fat, high-cholesterol diet on brain lipid profiles in apolipoprotein E E3 and E4 knock-in mice. Neurobiology of Aging, 34(9), 2217-2224, United States, Elsevier, DOI: 10.1016/j.neurobiolaging.2013.03.012.
Martins, I., Lim, F., Wilson, A., Laws, S., Martins, R., (2013), The acceleration of aging and Alzheimer’s disease through the biological mechanisms behind obesity and type II diabetes. Health, 5(5), 913-920, United States of America, Scientific Research Publishing, Inc., DOI: 10.4236/health.2013.55121.
Research Student Supervision
Doctor of Philosophy, Identification Of Plasma Lipid Biomarkers In Alzheimer's Disease.